Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling (Q34361655)

1 August 2017

title

Novel roles of TLR3 tyrosine phosphorylation and PI3 kinase in double-stranded RNA signaling (English)

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1 August 2017

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Saumendra N Sarkar

1

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author name string

Kristi L Peters

2

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1 August 2017

Christopher P Elco

3

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1 August 2017

Shuji Sakamoto

4

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1 August 2017

Srabani Pal

5

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1 August 2017

Ganes C Sen

6

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1 August 2017

language of work or name

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24 October 2004

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Nature Structural & Molecular Biology

1 August 2017

published in

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1 August 2017

volume

11

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1 August 2017

issue

11

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1 August 2017

page(s)

1060-1067

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1 August 2017

cites work

Viruses and interferons

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A comprehensive view of regulation of gene expression by double-stranded RNA-mediated cell signaling

21 January 2018

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IRF-3-dependent, NFkappa B- and JNK-independent activation of the 561 and IFN-beta genes in response to double-stranded RNA

21 January 2018

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

21 January 2018

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Triggering the interferon antiviral response through an IKK-related pathway

21 January 2018

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IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

21 January 2018

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

21 January 2018

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Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

21 January 2018

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Toll/IL-1 receptor domain-containing adaptor inducing IFN-beta (TRIF) associates with TNF receptor-associated factor 6 and TANK-binding kinase 1, and activates two distinct transcription factors, NF-kappa B and IFN-regulatory factor-3...

21 January 2018

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Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta

21 January 2018

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Double-stranded RNA signaling by Toll-like receptor 3 requires specific tyrosine residues in its cytoplasmic domain

21 January 2018

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Control of IRF-3 activation by phosphorylation

21 January 2018

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Multiple signaling pathways leading to the activation of interferon regulatory factor 3.

21 January 2018

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Identification of the minimal phosphoacceptor site required for in vivo activation of interferon regulatory factor 3 in response to virus and double-stranded RNA.

21 January 2018

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Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1.

21 January 2018

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Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

21 January 2018

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The role of PI3K in immune cells

21 January 2018

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Toll-like receptor 2-mediated NF-kappa B activation requires a Rac1-dependent pathway

21 January 2018

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Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

21 January 2018

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LPS-TLR4 signaling to IRF-3/7 and NF-kappaB involves the toll adapters TRAM and TRIF

21 January 2018

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The phosphatidylinositol 3-kinase-Akt pathway limits lipopolysaccharide activation of signaling pathways and expression of inflammatory mediators in human monocytic cells

21 January 2018

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Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains

21 January 2018

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Transcriptional activity of interferon regulatory factor (IRF)-3 depends on multiple protein-protein interactions

21 January 2018

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Crystal structure of IRF-3 reveals mechanism of autoinhibition and virus-induced phosphoactivation

21 January 2018

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Roles of phosphatidylinositol 3-kinase in interferon-gamma-dependent phosphorylation of STAT1 on serine 727 and activation of gene expression

21 January 2018

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Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

21 January 2018

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Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

21 January 2018

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p38-dependent activation of interferon regulatory factor 3 by lipopolysaccharide

21 January 2018

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

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Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways

21 January 2018

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Post-transcriptional regulation of cyclin D1 expression during G2 phase

21 January 2018

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Transcriptional Induction by Double-stranded RNA Is Mediated by Interferon-stimulated Response Elements without Activation of Interferon-stimulated Gene Factor 3

21 January 2018

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Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NSMB847

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Dimensions Publication ID

1 August 2017

1043591886

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Fatcat ID

release_igvknc2cabdyxla5y6gqs6w2cy

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Fatcat

https://api.fatcat.wiki/v0/release/igvknc2cabdyxla5y6gqs6w2cy

mapped directly with Wikidata item

24 November 2022

based on heuristic

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