An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects (Q34387297)

1 August 2017

title

An analysis of phenotypic variation in the familial cancer syndrome von Hippel-Lindau disease: evidence for modifier effects (English)

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von Hippel-Lindau disease

1 August 2017

main subject

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A R Webster

1

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1 August 2017

F M Richards

2

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1 August 2017

F E MacRonald

3

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1 August 2017

A T Moore

4

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1 August 2017

E R Maher

5

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1 August 2017

language of work or name

English

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publication date

1 October 1998

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American Journal of Human Genetics

1 August 2017

published in

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1 August 2017

volume

63

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1 August 2017

issue

4

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1 August 2017

page(s)

1025-1035

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Inactivation of the von Hippel-Lindau (VHL) tumour suppressor gene and allelic losses at chromosome arm 3p in primary renal cell carcinoma: evidence for a VHL-independent pathway in clear cell renal tumourigenesis

1 August 2017

cites work

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Somatic inactivation of the VHL gene in Von Hippel-Lindau disease tumors.

6 July 2018

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Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences

6 July 2018

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Mom1 is a semi-dominant modifier of intestinal adenoma size and multiplicity in Min/+ mice

6 July 2018

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Germline mutations in the Von Hippel-Lindau disease (VHL) gene in families from North America, Europe, and Japan

6 July 2018

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Expression of the von Hippel-Lindau disease tumour suppressor gene during human embryogenesis

6 July 2018

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Phenotypic expression in von Hippel-Lindau disease: correlations with germline VHL gene mutations

6 July 2018

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Identification of the von Hippel-Lindau disease tumor suppressor gene

6 July 2018

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Relationship between the GSTM1 genetic polymorphism and susceptibility to bladder, breast and colon cancer

6 July 2018

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Homozygous deletion of gene for glutathione S-transferase M1 in bladder cancer.

6 July 2018

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An analysis of variation in expression of neurofibromatosis (NF) type 1 (NF1): evidence for modifying genes.

6 July 2018

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Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse

6 July 2018

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Somatic mutations of the von Hippel-Lindau tumor suppressor gene in sporadic central nervous system hemangioblastomas.

6 July 2018

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Detailed mapping of germline deletions of the von Hippel-Lindau disease tumour suppressor gene

6 July 2018

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6 July 2018

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Identification of intragenic mutations in the von Hippel-Lindau disease tumour suppressor gene and correlation with disease phenotype

6 July 2018

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Germ-line mutations in the von Hippel-Lindau tumor-suppressor gene are similar to somatic von Hippel-Lindau aberrations in sporadic renal cell carcinoma.

6 July 2018

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Silencing of the VHL tumor-suppressor gene by DNA methylation in renal carcinoma

6 July 2018

1 reference

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Mutations of the VHL tumour suppressor gene in renal carcinoma

6 July 2018

1 reference

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Polymorphism in CYP1A1 and CYP2D6 genes: possible association with susceptibility to lung cancer

6 July 2018

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Somatic mutations of the von Hippel-Lindau disease tumour suppressor gene in non-familial clear cell renal carcinoma

6 July 2018

1 reference

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Von Hippel-Lindau (VHL) disease with pheochromocytoma in the Black Forest region of Germany: evidence for a founder effect

6 July 2018

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Diagnosis of polymorphisms in carcinogen-activating and inactivating enzymes and cancer susceptibility-a review

6 July 2018

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Mutation and cancer: statistical study of retinoblastoma

6 July 2018

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Clinical features and natural history of von Hippel-Lindau disease

6 July 2018

1 reference

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Glutathione S-transferase mu locus: use of genotyping and phenotyping assays to assess association with lung cancer susceptibility.

6 July 2018

1 reference

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Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility

6 July 2018

1 reference

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Isolation and characterization of 19 dinucleotide repeat polymorphisms on chromosome 3p.

6 July 2018

1 reference

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Molecular analysis of de novo germline mutations in the von Hippel-Lindau disease gene.

6 July 2018

1 reference

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Germline mutations in the von Hippel-Lindau disease tumor suppressor gene: correlations with phenotype

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1377470

Molecular genetic investigations of the mechanism of tumourigenesis in von Hippel-Lindau disease: analysis of allele loss in VHL tumours

27 October 2018

1 reference

12 December 2020

CYP2D6 genes and risk of liver cancer

1 reference

12 December 2020

Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus

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12 December 2020

Mutation of the Von Hippel-Lindau tumour suppressor gene in capillary haemangioblastomas of the central nervous system

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12 December 2020

Increased risk for hepatocellular carcinoma in NAT2-slow acetylators and CYP2D6-rapid metabolizers

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12 December 2020

von Hippel-Lindau disease

1 reference

12 December 2020

Identifiers

DOI

10.1086/302037

1 reference

1 August 2017

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1 August 2017

1 reference