Phosphorylation independent activation of human cyclin-dependent kinase 2 by cyclin A in vitro (Q34435398)

2 August 2017

title

Phosphorylation independent activation of human cyclin-dependent kinase 2 by cyclin A in vitro (English)

1 reference

2 August 2017

1 reference

L Connell-Crowley

1

1 reference

2 August 2017

M J Solomon

series ordinal

2

1 reference

2 August 2017

N Wei

series ordinal

3

1 reference

2 August 2017

J W Harper

series ordinal

4

1 reference

2 August 2017

publication date

1 January 1993

1 reference

Molecular Biology of the Cell

2 August 2017

published in

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2 August 2017

volume

4

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2 August 2017

issue

1

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2 August 2017

page(s)

79-92

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Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2

2 August 2017

cites work

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6 July 2018

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Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis

6 July 2018

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6 July 2018

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Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis

6 July 2018

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Human cDNAs encoding homologs of the small p34Cdc28/Cdc2-associated protein of Saccharomyces cerevisiae and Schizosaccharomyces pombe

6 July 2018

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6 July 2018

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p34cdc2: the S and M kinase?

6 July 2018

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6 July 2018

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G1-specific cyclins of S. cerevisiae: cell cycle periodicity, regulation by mating pheromone, and association with the p34CDC28 protein kinase

6 July 2018

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Universal control mechanism regulating onset of M-phase

6 July 2018

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Association of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase requires a negatively charged side group at a conserved threonine

6 July 2018

1 reference

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Cyclin is a component of maturation-promoting factor from Xenopus

6 July 2018

1 reference

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Hepatitis B virus integration in a cyclin A gene in a hepatocellular carcinoma

6 July 2018

1 reference

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

6 July 2018

1 reference

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Crystal Structure of the Catalytic Subunit of Cyclic Adenosine Monophosphate-Dependent Protein Kinase

6 July 2018

1 reference

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Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

A cyclin B homolog in S. cerevisiae: Chronic activation of the Cdc28 protein kinase by cyclin prevents exit from mitosis

6 July 2018

1 reference

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The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae

6 July 2018

1 reference

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Differential phosphorylation of vertebrate p34cdc2 kinase at the G1/S and G2/M transitions of the cell cycle: identification of major phosphorylation sites

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cyclin a is required for the onset of DNA replication in mammalian fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

cdc2 phosphorylation is required for its interaction with cyclin.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

6 July 2018

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Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Activation of p34cdc2 kinase by cyclin A

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system

6 July 2018

1 reference

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Identification of cellular proteins that can interact specifically with the T/ElA-binding region of the retinoblastoma gene product

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cloning of a human cDNA encoding a CDC2-related kinase by complementation of a budding yeast cdc28 mutation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cyclin B targets p34cdc2 for tyrosine phosphorylation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cloning by differential screening of a Xenopus cDNA coding for a protein highly homologous to cdc2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Phosphorylation at Thr167 is required for Schizosaccharomyces pombe p34cdc2 function

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Evidence that the G1-S and G2-M transitions are controlled by different cdc2 proteins in higher eukaryotes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Activation of human cyclin-dependent kinases in vitro

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Human cyclin-dependent kinase 2 is activated during the S and G2 phases of the cell cycle and associates with cyclin A.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Role of phosphorylation in p34cdc2 activation: identification of an activating kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cyclin A is required in S phase in normal epithelial cells.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Inactivation of the p34cdc2-cyclin B complex by the human WEE1 tyrosine kinase

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

cdc25+ encodes a protein phosphatase that dephosphorylates p34cdc2

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

Cyclin A is required at two points in the human cell cycle

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=300902

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

6 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8443411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biochemical characterization of the p34cdc2 protein kinase component of purified maturation-promoting factor from Xenopus eggs

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8443411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of mitosis by cyclic accumulation of p80 cdc25 mitotic inducer in fission yeast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/8443411

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.4.1.79

1 reference

2 August 2017

1 reference

2 August 2017

1 reference