IFN-λ4: the paradoxical new member of the interferon lambda family (Q34439917)

2 August 2017

title

IFN-λ4: the paradoxical new member of the interferon lambda family (English)

1 reference

2 August 2017

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Ludmila Prokunina-Olsson

object named as

Ludmila Prokunina-Olsson

series ordinal

2

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Raymond P. Donnelly

object named as

Raymond P Donnelly

series ordinal

3

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author name string

Thomas R O'Brien

series ordinal

1

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2 August 2017

language of work or name

English

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publication date

30 April 2014

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Journal of Interferon and Cytokine Research

2 August 2017

published in

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2 August 2017

volume

34

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2 August 2017

issue

11

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2 August 2017

page(s)

829-838

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IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies

2 August 2017

cites work

1 reference

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Interferon-lambda4 genetic polymorphism is associated with the therapy response for hepatitis C virus recurrence after a living donor liver transplant

6 July 2018

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6 July 2018

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6 July 2018

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IFNL4-ΔG genotype is associated with slower viral clearance in hepatitis C, genotype-1 patients treated with sofosbuvir and ribavirin

6 July 2018

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Hepatic interferon-stimulated genes are differentially regulated in the liver of chronic hepatitis C patients with different interleukin-28B genotypes

6 July 2018

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The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs

6 July 2018

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6 July 2018

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Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses

6 July 2018

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IFNL4 ss469415590 variant is a better predictor than rs12979860 of pegylated interferon-alpha/ribavirin therapy failure in hepatitis C virus/HIV-1 coinfected patients

6 July 2018

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Association of the IFNL4-ΔG Allele With Impaired Spontaneous Clearance of Hepatitis C Virus

6 July 2018

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A systematic analysis of host factors reveals a Med23-interferon-λ regulatory axis against herpes simplex virus type 1 replication

6 July 2018

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6 July 2018

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6 July 2018

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IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction

6 July 2018

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A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

6 July 2018

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Interferon-lambda (IFN-λ) induces signal transduction and gene expression in human hepatocytes, but not in lymphocytes or monocytes

6 July 2018

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Analysis of IL28B variants in an Egyptian population defines the 20 kilobases minimal region involved in spontaneous clearance of hepatitis C virus

6 July 2018

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6 July 2018

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Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients

6 July 2018

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6 July 2018

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USP18-based negative feedback control is induced by type I and type III interferons and specifically inactivates interferon α response

6 July 2018

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IFN-lambda determines the intestinal epithelial antiviral host defense

6 July 2018

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Interferon-β and interferon-λ signaling is not affected by interferon-induced refractoriness to interferon-α in vivo

6 July 2018

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Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus

6 July 2018

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Regulatory Effects of Ribosomal S6 Kinase 1 (RSK1) in IFNλ Signaling

6 July 2018

1 reference

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IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection

6 July 2018

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Crystal Structure of Human Interferon-λ1 in Complex with Its High-Affinity Receptor Interferon-λR1

6 July 2018

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IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

6 July 2018

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Interferon-lambda: a new addition to an old family

6 July 2018

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Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virus

6 July 2018

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Lambda interferon renders epithelial cells of the respiratory and gastrointestinal tracts resistant to viral infections

6 July 2018

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Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study

6 July 2018

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Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

6 July 2018

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IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C

6 July 2018

1 reference

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Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Interferon- Is Functionally an Interferon but Structurally Related to the Interleukin-10 Family

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

The role of genomic data in the discovery, annotation and evolutionary interpretation of the interferon-lambda family

6 July 2018

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Human interferon-lambda3 is a potent member of the type III interferon family.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo

6 July 2018

1 reference

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Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases

6 July 2018

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Interferons alpha and lambda inhibit hepatitis C virus replication with distinct signal transduction and gene regulation kinetics

6 July 2018

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Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Antiviral activity of transiently expressed IFN-kappa is cell-associated

6 July 2018

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Global epidemiology of hepatitis C virus infection

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Biological activity of interleukins-28 and -29: comparison with type I interferons

6 July 2018

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IFN-lambdas mediate antiviral protection through a distinct class II cytokine receptor complex

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

IL-28, IL-29 and their class II cytokine receptor IL-28R

6 July 2018

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One more piece in the interleukin 28B gene puzzle? The case of hepatitis B.

6 July 2018

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New genetic discoveries and treatment for hepatitis C.

27 October 2018

1 reference

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Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Variants in IL28B in liver recipients and donors correlate with response to peg-interferon and ribavirin therapy for recurrent hepatitis C.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Phase 1b study of pegylated interferon lambda 1 with or without ribavirin in patients with chronic genotype 1 hepatitis C virus infection

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Hepatic ISG expression is associated with genetic variation in interleukin 28B and the outcome of IFN therapy for chronic hepatitis C.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4217005

Only just the beginning of the end of hepatitis C

27 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24786669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL28B polymorphisms are not associated with the response to interferon-β in multiple sclerosis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24786669

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1089/JIR.2013.0136

1 reference

2 August 2017

1 reference

2 August 2017

1 reference