Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation (Q34446515)

2 August 2017

title

Ablation of telomerase and telomere loss leads to cardiac dilatation and heart failure associated with p53 upregulation (English)

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2 August 2017

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9

Piero Anversa

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2 August 2017

8

Jan Kajstura

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Annarosa Leri

1

object named as

Annarosa Leri

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Maria A Blasco

object named as

María A Blasco

10

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Bernardo Nadal-Ginard

7

object named as

Bernardo Nadal-Ginard

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2 August 2017

Annarosa Leri

1

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2 August 2017

Sonia Franco

2

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2 August 2017

Antonella Zacheo

3

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2 August 2017

Laura Barlucchi

4

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2 August 2017

Stefano Chimenti

5

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2 August 2017

Federica Limana

6

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2 August 2017

Jan Kajstura

8

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2 August 2017

language of work or name

English

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publication date

1 January 2003

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2 August 2017

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2 August 2017

volume

22

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2 August 2017

issue

1

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2 August 2017

page(s)

131-139

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Different telomere damage signaling pathways in human and mouse cells

2 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Many ways to telomere dysfunction: in vivo studies using mouse models

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomerase in the human organism

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

New ways not to make ends meet: telomerase, DNA damage proteins and heterochromatin

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Protection of mammalian telomeres

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Myocyte renewal and ventricular remodelling

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Restoration of telomerase activity rescues chromosomal instability and premature aging in Terc-/- mice with short telomeres.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Mobilized bone marrow cells repair the infarcted heart, improving function and survival

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Evidence that human cardiac myocytes divide after myocardial infarction

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Bone marrow cells regenerate infarcted myocardium

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomere length abnormalities in mammalian radiosensitive cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Impaired germinal center reaction in mice with short telomeres.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Disease states associated with telomerase deficiency appear earlier in mice with short telomeres

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Overexpression of insulin-like growth factor-1 attenuates the myocyte renin-angiotensin system in transgenic mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Myocyte proliferation in end-stage cardiac failure in humans

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Essential role of mouse telomerase in highly proliferative organs

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Extension of life-span by introduction of telomerase into normal human cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomeres shorten during ageing of human fibroblasts

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Telomerase-deficient mice with short telomeres are resistant to skin tumorigenesis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=140062

Chimerism of the transplanted heart

27 October 2018

1 reference

12 December 2020

The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability

1 reference

12 December 2020

Decreased B16F10 melanoma growth and impaired vascularization in telomerase-deficient mice with critically short telomeres

1 reference

12 December 2020

Long-term repopulating ability of telomerase-deficient murine hematopoietic stem cells

1 reference

12 December 2020

Telomerase beyond telomeres

1 reference

12 December 2020

Necrotic and apoptotic myocyte cell death in the aging heart of Fischer 344 rats

1 reference

12 December 2020

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

1 reference

12 December 2020

Myocyte death in the failing human heart is gender dependent

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/CDG013

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2 August 2017

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2 August 2017

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