Telomeric recombination induced by dysfunctional telomeres (Q34489869)

2 August 2017

title

Telomeric recombination induced by dysfunctional telomeres (English)

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2 August 2017

2

Chantal Autexier

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2 August 2017

Marie Eve Brault

1

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2 August 2017

publication date

30 November 2010

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Molecular Biology of the Cell

2 August 2017

published in

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2 August 2017

volume

22

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2 August 2017

issue

2

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2 August 2017

page(s)

179-188

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Assaying and investigating Alternative Lengthening of Telomeres activity in human cells and cancers.

2 August 2017

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Short telomeres initiate telomere recombination in primary and tumor cells

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6 July 2018

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6 July 2018

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Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells

6 July 2018

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6 July 2018

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6 July 2018

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A novel telomere structure in a human alternative lengthening of telomeres cell line

6 July 2018

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Telomeric DNA in ALT cells is characterized by free telomeric circles and heterogeneous t-loops

6 July 2018

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Homologous recombination generates T-loop-sized deletions at human telomeres

6 July 2018

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Telomeric recombination in mismatch repair deficient human colon cancer cells after telomerase inhibition

6 July 2018

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6 July 2018

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Alternative lengthening of telomeres is characterized by high rates of telomeric exchange.

6 July 2018

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DNA binding features of human POT1: a nonamer 5'-TAGGGTTAG-3' minimal binding site, sequence specificity, and internal binding to multimeric sites

6 July 2018

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A DNA damage checkpoint response in telomere-initiated senescence

6 July 2018

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DNA damage foci at dysfunctional telomeres

6 July 2018

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Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression

6 July 2018

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Different telomere damage signaling pathways in human and mouse cells

6 July 2018

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Cdc13 prevents telomere uncapping and Rad50-dependent homologous recombination

6 July 2018

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Effects of reconstitution of telomerase activity on telomere maintenance by the alternative lengthening of telomeres (ALT) pathway

6 July 2018

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Telomere maintenance by telomerase and by recombination can coexist in human cells

6 July 2018

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A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation

6 July 2018

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Coexistence of alternative lengthening of telomeres and telomerase in hTERT-transfected GM847 cells

6 July 2018

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Expression of mutant telomerase in immortal telomerase-negative human cells results in cell cycle deregulation, nuclear and chromosomal abnormalities and rapid loss of viability

6 July 2018

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Transient expression of wild-type or biologically inactive telomerase allows the formation of artificial telomeres in mortal human cells

6 July 2018

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Two survivor pathways that allow growth in the absence of telomerase are generated by distinct telomere recombination events

6 July 2018

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Telomere maintenance by recombination in human cells.

6 July 2018

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Telomere maintenance in telomerase-deficient mouse embryonic stem cells: characterization of an amplified telomeric DNA

6 July 2018

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Telomere-telomere recombination is an efficient bypass pathway for telomere maintenance in Saccharomyces cerevisiae

6 July 2018

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TRF1 binds a bipartite telomeric site with extreme spatial flexibility

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020914

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3020914

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice

6 July 2018

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Telomerase activity and telomere lengths in various cell lines: changes of telomerase activity can be another method for chemosensitivity evaluation

6 July 2018

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Release of telomeric DNA from chromosomes in immortal human cells lacking telomerase activity

6 July 2018

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Extra-chromosomal telomere repeat DNA in telomerase-negative immortalized cell lines

6 July 2018

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Reprogramming of telomerase by expression of mutant telomerase RNA template in human cells leads to altered telomeres that correlate with reduced cell viability

6 July 2018

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A survey of telomerase activity in human cancer

6 July 2018

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Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening

6 July 2018

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Telomere elongation in immortal human cells without detectable telomerase activity

6 July 2018

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6 July 2018

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Origin of Concatemeric T7DNA

6 July 2018

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ATM mediates cytotoxicity of a mutant telomerase RNA in human cancer cells

6 July 2018

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Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma.

27 October 2018

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Telomerase-independent telomere length maintenance in the absence of alternative lengthening of telomeres-associated promyelocytic leukemia bodies

27 October 2018

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Rapid inhibition of cancer cell growth induced by lentiviral delivery and expression of mutant-template telomerase RNA and anti-telomerase short-interfering RNA.

27 October 2018

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Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme.

27 October 2018

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Inhibition of telomerase limits the growth of human cancer cells.

27 October 2018

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Ku70 stimulates fusion of dysfunctional telomeres yet protects chromosome ends from homologous recombination

27 October 2018

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Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body

9 December 2018

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12 December 2020

Telomere Maintenance Mechanisms in Liposarcomas: Association with Histologic Subtypes and Disease Progression

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12 December 2020

The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres

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12 December 2020

Telomerase-independent lengthening of yeast telomeres occurs by an abrupt Rad50p-dependent, Rif-inhibited recombinational process

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12 December 2020

Identifiers

DOI

10.1091/MBC.E10-02-0173

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2 August 2017

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2 August 2017

1 reference