Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects (Q34498198)

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English	Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects	scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Effect of the phosphodiesterase 5 inhibitors sildenafil, tadalafil and vardenafil on rat anococcygeus muscle: functional and biochemical aspects (English)

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

author name string

Haroldo A Toque

1

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Fernanda B M Priviero

2

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Saiprasad M Zemse

3

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Edson Antunes

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Cleber E Teixeira

5

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

R Clinton Webb

6

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Europe PubMed Central

PubMed publication ID

2 August 2017

language of work or name

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based on heuristic

inferred from title

publication date

15 October 2008

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Europe PubMed Central

PubMed publication ID

2 August 2017

Clinical and Experimental Pharmacology and Physiology

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Europe PubMed Central

PubMed publication ID

2 August 2017

36

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Europe PubMed Central

PubMed publication ID

2 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

358-366

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

Vardenafil, but not sildenafil or tadalafil, has calcium-channel blocking activity in rabbit isolated pulmonary artery and human washed platelets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Drug Insight: oral phosphodiesterase type 5 inhibitors for erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Phosphodiesterase type 5 inhibitors for erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Past, present, and future: a 7-year update of Viagra (sildenafil citrate).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

The use of phosphodiesterase type 5 inhibitors for erectile dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Overview of phosphodiesterase 5 inhibition in erectile dysfunction

1 reference

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7 July 2018

Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Cyclic GMP phosphodiesterases and regulation of smooth muscle function

1 reference

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7 July 2018

Cyclic nucleotide phosphodiesterase activity, expression, and targeting in cells of the cardiovascular system

1 reference

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7 July 2018

The pharmacology of nitric oxide in the peripheral nervous system of blood vessels

1 reference

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7 July 2018

Pharmacology of phosphodiesterase 5 inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Sildenafil (Viagra) augments sodium nitroprusside-induced but not nitroglycerin-induced hypotension in dogs

1 reference

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7 July 2018

The phosphodiesterase inhibitory selectivity and the in vitro and in vivo potency of the new PDE5 inhibitor vardenafil

1 reference

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7 July 2018

Pharmacology of penile erection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Biology of the anococcygeus muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Effect of sildenafil on non-adrenergic non-cholinergic neurotransmission in bovine penile small arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Phosphodiesterase 5 inhibitors and nitrergic transmission-from zaprinast to sildenafil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Cyclic nucleotide phosphodiesterases: relating structure and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

No evidence for a significant non-nitrergic, hyperpolarising factor contribution to field stimulation-induced relaxation of the mouse anococcygeus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Inhibition of nitrergic relaxations by a selective inhibitor of the soluble guanylate cyclase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Rat anococcygeus: a dynamic smooth muscle preparation for experimental pharmacology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Physiology of penile erection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Nitric oxide synthase and nitric oxide-mediated effects in lower urinary tract smooth muscles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

The rat anococcygeus muscle and its response to nerve stimulation and to some drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

The effects of L-arginine and NG-monomethyl L-arginine on the response of the rat anococcygeus muscle to NANC nerve stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Innervation of the anococcygeus muscle of the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Characterization of nitric oxide synthases in non-adrenergic non-cholinergic nerve containing tissue from the rat anococcygeus muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Constitutive and inducible nitric oxide synthases incorporate molecular oxygen into both nitric oxide and citrulline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

7 July 2018

Phosphodiesterase 5 in the female pig and human urethra: morphological and functional aspects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Stimulation of soluble guanylyl cyclase by BAY 41-2272 relaxes anococcygeus muscle: interaction with nitric oxide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Relaxant effect of sildenafil in the rabbit basilar artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Differential effects of the phosphodiesterase type 5 inhibitors sildenafil, vardenafil, and tadalafil in rat aorta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Ca2+ sensitization and the regulation of contractility in rat anococcygeus and retractor penis muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Vardenafil is effective and well-tolerated for treating erectile dysfunction in a broad population of men, irrespective of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Erectile response with vardenafil in sildenafil nonresponders: a multicentre, double-blind, 12-week, flexible-dose, placebo-controlled erectile dysfunction clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Binding of tritiated sildenafil, tadalafil, or vardenafil to the phosphodiesterase-5 catalytic site displays potency, specificity, heterogeneity, and cGMP stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Pro-erectile effect of vardenafil: in vitro experiments in rabbits and in vivo comparison with sildenafil in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

[3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Interactions of sildenafil with various coronary vasodilators in isolated porcine coronary artery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

The effect of sildenafil on corpus cavernosal smooth muscle relaxation and cyclic GMP formation in the diabetic rabbit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Sildenafil relaxes rabbit clitoral corpus cavernosum.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

Evidence for a role of nitric oxide in the neurotransmitter system mediating relaxation of the rat anococcygeus muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022481

27 October 2018

NADPH-diaphorase reactivity in nerves supplying the rat anococcygeus muscle

1 reference

https://pubmed.ncbi.nlm.nih.gov/18986324

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of sildenafil on the relaxation of human corpus cavernosum tissue in vitro and on the activities of cyclic nucleotide phosphodiesterase isozymes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18986324

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic GMP as substrate and regulator of cyclic nucleotide phosphodiesterases (PDEs)

1 reference

https://pubmed.ncbi.nlm.nih.gov/18986324

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of direct relaxant effect of sildenafil, tadalafil and vardenafil on corpus cavernosum

1 reference

https://pubmed.ncbi.nlm.nih.gov/18986324

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sildenafil citrate on nitrergic transmission in anococcygeus muscles from the urogenital system of male and female mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/18986324

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1440-1681.2008.05071.X

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

ResearchGate publication ID

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