Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions (Q34527799)

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English	Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

2 August 2017

Chronic hyperglycemia is associated with impaired glucose influence on insulin secretion. A study in normal rats using chronic in vivo glucose infusions (English)

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Europe PubMed Central

PubMed publication ID

2 August 2017

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author name string

J L Leahy

1

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Europe PubMed Central

PubMed publication ID

2 August 2017

H E Cooper

2

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2 August 2017

D A Deal

3

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2 August 2017

G C Weir

4

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2 August 2017

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publication date

1 March 1986

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2 August 2017

Journal of Clinical Investigation

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2 August 2017

77

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Europe PubMed Central

PubMed publication ID

2 August 2017

3

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Europe PubMed Central

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2 August 2017

908-915

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Europe PubMed Central

PubMed publication ID

2 August 2017

The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused Pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

A simple and inexpensive membrane "lung" for small organ perfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Glucagon secretion from the perfused rat pancreas. Studies with glucose and catecholamines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Modulation of proinsulin messenger RNA after partial pancreatectomy in rats. Relationships to glucose homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Adrenergically mediated intrapancreatic control of the glucagon response to glucopenia in the isolated rat pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Effect of Continuous Insulin Infusion with an Implantable Seven-Day Minipump in the Diabetic Chinese Hamster*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Direct Effect of Insulin on Secretion of Insulin, Glucagon, Gastric Inhibitory Polypeptide, and Gastrin during Maintenance of Normoglycemia*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Persisting Enhanced Proinsulin-insulin and Protein Biosynthesis (3H-Leucine Incorporation) by Pancreatic Islets of the Rat after Glucose Exposure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Adrenergic modulation of pancreatic A, B, and D cells alpha-Adrenergic suppression and beta-adrenergic stimulation of somatostatin secretion, alpha-adrenergic stimulation of glucagon secretion in the perfused dog pancreas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

7 July 2018

Islet changes induced by hyperglycemia in rats. Effect of insulin or chlorpropamide therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

27 October 2018

Hormonal and non-hormonal protein biosynthesis in the pancreatic beta cell of the intact rat after prolonged hyperglycaemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423478

27 October 2018

Evidence for a Feedback Inhibition of Insulin on Insulin Secretion in the Isolated, Perfused Canine Pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A sensitive, precise radioimmunoassay of serum insulin relying on charcoal separation of bound and free hormone moieties

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of large amounts of noradrenaline from the isolated perfused canine pancreas during glucose deprivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucose oxidation (14-CO2 production)and insulin secretion by pancreatic islets isolated from hyperglycemic and normoglycemic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Influence of glucose infusions on proinsulin and insulin syntheses in the islands of langerhans in the rat]

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Responses of Neonatal Rat Islets to Streptozotocin: Limited B-Cell Regeneration and Hyperglycemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet Secretion in a New Experimental Model for Non-insulin-dependent Diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal Islet and Adipocyte Function in Young B-cell-deficient Rats with Near-Normoglycemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-dependent inhibition of insulin release: glucose-arginine interactions in the perfused rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal Glucose Regulation of Insulin Secretion in Models of Reduced B-Cell Mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged hyperglycaemia during infusion of glucose and somatostatin impairs pancreatic A- and B-cell responses to decrements in plasma glucose in normal man: evidence for induction of altered sensitivity to glucose

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dual action of glucose on the cytosolic Ca2+ activity in pancreatic beta-cells. Demonstration of an inhibitory effect of glucose on insulin release in the mouse and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unresponsiveness to glucose in a streptozocin model of diabetes. Inappropriate insulin and glucagon responses to a reduction of glucose concentration

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal Insulin Secretion in a Streptozocin Model of Diabetes: Effects of Insulin Treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beta-cell cytoplasmic Ca2+ balance as a determinant for glucose-stimulated insulin release

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between arginine and glucose in the induction of insulin secretion from the isolated, perfused rat pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/3512603

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1172/JCI112389

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

2 August 2017

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