Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells. (Q34529123)

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English	Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells.	scientific article

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15 December 2019

Human CD25+CD4+ T suppressor cell clones produce transforming growth factor beta, but not interleukin 10, and are distinct from type 1 T regulatory cells (English)

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15 December 2019

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Megan K. Levings

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15 December 2019

Manuela Battaglia

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15 December 2019

Maria Grazia Roncarolo

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15 December 2019

Claudia Sartirana

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Claudia Sartirana

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15 December 2019

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Romina Sangregorio

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15 December 2019

Anna Lisa Moschin

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15 December 2019

Paul C Orban

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15 December 2019

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1 November 2002

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15 December 2019

Journal of Experimental Medicine

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15 December 2019

196

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15 December 2019

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15 December 2019

1335-1346

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15 December 2019

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11 June 2022

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Phenotype, localization, and mechanism of suppression of CD4(+)CD25(+) human thymocytes

1 reference

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7 July 2018

Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

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7 July 2018

Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

1 reference

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7 July 2018

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

1 reference

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7 July 2018

CD4+ CD25+ suppressor T cells: more questions than answers

1 reference

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7 July 2018

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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7 July 2018

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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7 July 2018

Natural CD4+ CD25+ regulatory T cells. Their role in the control of superantigen responses

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7 July 2018

The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance

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7 July 2018

Type 1 T regulatory cells.

1 reference

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7 July 2018

Control of T-cell activation by CD4+ CD25+ suppressor T cells

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Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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7 July 2018

Human CD4(+)CD25(+) cells: a naturally occurring population of regulatory T cells.

1 reference

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7 July 2018

Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

1 reference

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Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood

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Human cd25(+)cd4(+) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

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Identification and functional characterization of human CD4(+)CD25(+) T cells with regulatory properties isolated from peripheral blood

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IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells.

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7 July 2018

Human CD4(+)CD25(+) thymocytes and peripheral T cells have immune suppressive activity in vitro

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific

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An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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High-efficiency gene transfer into normal and adenosine deaminase-deficient T lymphocytes is mediated by transduction on recombinant fibronectin fragments

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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Interleukin-10 induces a long-term antigen-specific anergic state in human CD4+ T cells

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Regulatory T cell clones induced by oral tolerance: suppression of autoimmune encephalomyelitis

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CD4+CD25high regulatory cells in human peripheral blood

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Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

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Human anergic/suppressive CD4(+)CD25(+) T cells: a highly differentiated and apoptosis-prone population

1 reference

https://pubmed.ncbi.nlm.nih.gov/12438424

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Control of intestinal inflammation by regulatory T cells

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https://pubmed.ncbi.nlm.nih.gov/12438424

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Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells

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https://pubmed.ncbi.nlm.nih.gov/12438424

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Anergic T cells act as suppressor cells in vitro and in vivo

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https://pubmed.ncbi.nlm.nih.gov/12438424

12 December 2020

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Molecular analysis of T cell repertoires. Spectratypes generated by multiplex polymerase chain reaction and evaluated by radioactivity or fluorescence

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Identifiers

10.1084/JEM.20021139

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Europe PubMed Central

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15 December 2019

PMC publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438424%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12438424%20AND%20SRC:MED&resulttype=core&format=json

15 December 2019

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