Progress and challenges for malaria vaccines (Q34521010)

2 August 2017

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title

Progress and challenges for malaria vaccines (English)

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2 August 2017

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Thomas L Richie

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Allan Saul

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Allan Saul

series ordinal

2

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language of work or name

English

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publication date

1 February 2002

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2 August 2017

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2 August 2017

volume

415

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2 August 2017

issue

6872

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2 August 2017

page(s)

694-701

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Plasma antibodies from malaria-exposed pregnant women recognize variant surface antigens on plasmodium falciparum-infected erythrocytes in a parity-dependent manner and block parasite adhesion to chondroitin sulfate A.

2 August 2017

cites work

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7 January 2021

Malaria transmission-blocking vaccines--how can their development be supported?

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7 January 2021

The role of variant surface antigens on malaria-infected red blood cells.

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7 January 2021

Protective Immunity produced by the Injection of X-irradiated Sporozoites of Plasmodium berghei

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7 January 2021

Sporozoite vaccine induces genetically restricted T cell elimination of malaria from hepatocytes

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7 January 2021

Host age as a determinant of naturally acquired immunity to Plasmodium falciparum

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7 January 2021

Naturally acquired antibodies to sporozoites do not prevent malaria: vaccine development implications

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7 January 2021

Gamma-globulin and acquired immunity to human malaria

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7 January 2021

Parasitologic and clinical human response to immunoglobulin administration in falciparum malaria.

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7 January 2021

Efficacy of recombinant circumsporozoite protein vaccine regimens against experimental Plasmodium falciparum malaria

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7 January 2021

Efficacy of two alternate vaccines based on Plasmodium falciparum merozoite surface protein 1 in an Aotus challenge trial

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7 January 2021

Antibodies to malaria vaccine candidates Pvs25 and Pvs28 completely block the ability of Plasmodium vivax to infect mosquitoes

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7 January 2021

The surface variant antigens of Plasmodium falciparum contain cross-reactive epitopes

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7 January 2021

Antigenic diversity of Plasmodium falciparum and antibody-mediated parasite neutralization

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7 January 2021

The complexity of protective immunity against liver-stage malaria

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7 January 2021

Transmission blocking malaria vaccines

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7 January 2021

Human malaria in immunocompromised mice: an in vivo model to study defense mechanisms against Plasmodium falciparum

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7 January 2021

Cytophilic immunoglobulin responses to Plasmodium falciparum glutamate-rich protein are correlated with protection against clinical malaria in Dielmo, Senegal

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7 January 2021

Malaria vaccine development: current status

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7 January 2021

Human phase I vaccine trials of 3 recombinant asexual stage malaria antigens with Montanide ISA720 adjuvant

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7 January 2021

Construction and immunogenicity in mice of attenuated Salmonella typhi expressing Plasmodium falciparum merozoite surface protein 1 (MSP-1) fused to tetanus toxin fragment C.

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7 January 2021

A totally synthetic polyoxime malaria vaccine containing Plasmodium falciparum B cell and universal T cell epitopes elicits immune responses in volunteers of diverse HLA types

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7 January 2021

A synthetic vaccine protects humans against challenge with asexual blood stages of Plasmodium falciparum malaria.

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7 January 2021

Efficacy of RTS,S/AS02 malaria vaccine against Plasmodium falciparum infection in semi-immune adult men in The Gambia: a randomised trial

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7 January 2021

Protection against malaria by immunization with plasmid DNA encoding circumsporozoite protein

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7 January 2021

Circumventing genetic restriction of protection against malaria with multigene DNA immunization: CD8+ cell-, interferon gamma-, and nitric oxide-dependent immunity

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7 January 2021

Enhanced immunogenicity for CD8+ T cell induction and complete protective efficacy of malaria DNA vaccination by boosting with modified vaccinia virus Ankara

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7 January 2021

Safety, tolerability and humoral immune responses after intramuscular administration of a malaria DNA vaccine to healthy adult volunteers

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7 January 2021

Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine

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7 January 2021

Induction of CD4(+) T cell-dependent CD8(+) type 1 responses in humans by a malaria DNA vaccine.

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7 January 2021

Multistage multiantigen heterologous prime boost vaccine for Plasmodium knowlesi malaria provides partial protection in rhesus macaques

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7 January 2021

First DNA malaria vaccine on trial in Africa

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7 January 2021

Malaria DNA vaccines in Aotus monkeys

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7 January 2021

Immunogenicity and in vitro protective efficacy of a recombinant multistage Plasmodium falciparum candidate vaccine

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7 January 2021

Enhancement of the immune response in rabbits to a malaria DNA vaccine by immunization with a needle-free jet device

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7 January 2021

A prime-boost immunisation regimen using DNA followed by recombinant modified vaccinia virus Ankara induces strong cellular immune responses against the Plasmodium falciparum TRAP antigen in chimpanzees

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7 January 2021

Codon optimization of gene fragments encoding Plasmodium falciparum merzoite proteins enhances DNA vaccine protein expression and immunogenicity in mice.

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7 January 2021

Induction of potent immune responses by cationic microparticles with adsorbed human immunodeficiency virus DNA vaccines

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7 January 2021

Gene gun intradermal DNA immunization followed by boosting with modified vaccinia virus Ankara: enhanced CD8+ T cell immunogenicity and protective efficacy in the influenza and malaria models

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7 January 2021

DNA immunization with Plasmodium falciparum serine repeat antigen: regulation of humoral immune response by coinoculation of cytokine expression plasmid

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7 January 2021

Improving protective immunity induced by DNA-based immunization: priming with antigen and GM-CSF-encoding plasmid DNA and boosting with antigen-expressing recombinant poxvirus

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7 January 2021

Synthetic oligodeoxynucleotides containing CpG motifs enhance immunogenicity of a peptide malaria vaccine in Aotus monkeys

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7 January 2021

Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination

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7 January 2021

Induction of CD8+ T cells using heterologous prime-boost immunisation strategies

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7 January 2021

Protection of Aotus monkeys by Plasmodium falciparum EBA-175 region II DNA prime-protein boost immunization regimen

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7 January 2021

Assessment of a vaccinia virus vectored multi-epitope live vaccine candidate for Plasmodium falciparum

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7 January 2021

Phase I/IIa safety, immunogenicity, and efficacy trial of NYVAC-Pf7, a pox-vectored, multiantigen, multistage vaccine candidate for Plasmodium falciparum malaria.

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7 January 2021

Interferon-gamma-independent CD8+ T cell-mediated protective anti-malaria immunity elicited by recombinant adenovirus

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7 January 2021

Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles

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7 January 2021

Are trials in New World monkeys on the critical path for blood-stage malaria vaccine development?

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7 January 2021

New World monkey efficacy trials for malaria vaccine development: critical path or detour?

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7 January 2021

The epidemiology of malaria in the Wosera area, East Sepik Province, Papua New Guinea, in preparation for vaccine trials. II. Mortality and morbidity.

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7 January 2021

Child mortality and malaria transmission intensity in Africa

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7 January 2021

Clinical manifestations of Plasmodium falciparum malaria experimentally induced by mosquito challenge

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7 January 2021

European malaria vaccine initiative

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7 January 2021

The Global Alliance for Vaccines and Immunization--a millennial challenge

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7 January 2021

Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.

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7 January 2021

Naturally acquired antibody responses to Plasmodium falciparum merozoite surface protein 4 in a population living in an area of endemicity in Vietnam

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7 January 2021

Biochemical, biophysical, and functional characterization of bacterially expressed and refolded receptor binding domain of Plasmodium vivax duffy-binding protein

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7 January 2021

Specificity of the protective antibody response to apical membrane antigen 1

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7 January 2021

Plasmodium falciparum: an epitope within a highly conserved region of the 47-kDa amino-terminal domain of the serine repeat antigen is a target of parasite-inhibitory antibodies

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7 January 2021

Specificities of antibodies that inhibit merozoite dispersal from malaria-infected erythrocytes

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7 January 2021

A robust neutralization test for Plasmodium falciparum malaria

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7 January 2021

Antibodies against merozoite surface protein (MSP)-1(19) are a major component of the invasion-inhibitory response in individuals immune to malaria.

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7 January 2021

Molecular mechanisms of Plasmodium falciparum placental adhesion.

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7 January 2021

Neutralizing monoclonal antibodies to glycosylphosphatidylinositol, the dominant TNF-alpha-inducing toxin of Plasmodium falciparum: prospects for the immunotherapy of severe malaria.

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7 January 2021

DNA-based vaccines against malaria: status and promise of the Multi-Stage Malaria DNA Vaccine Operation

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7 January 2021

Identifiers

DOI

10.1038/415694A

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Dimensions Publication ID

2 August 2017

1036155209

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