CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. (Q34554035)

3 August 2017

title

CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2. (English)

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3 August 2017

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Xuguang Tai

1

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3 August 2017

Michelle Cowan

series ordinal

2

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3 August 2017

Lionel Feigenbaum

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3

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3 August 2017

Alfred Singer

series ordinal

4

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3 August 2017

language of work or name

English

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publication date

9 January 2005

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3 August 2017

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3 August 2017

volume

6

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3 August 2017

issue

2

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3 August 2017

page(s)

152-162

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The effect of thymus environment on T cell development and tolerance

3 August 2017

cites work

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7 January 2021

A nondeletional mechanism of thymic self tolerance

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7 January 2021

Clonal deletion and clonal anergy in the thymus induced by cellular elements with different radiation sensitivities

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7 January 2021

Peripheral expression of self-MHC-II influences the reactivity and self-tolerance of mature CD4(+) T cells: evidence from a lymphopenic T cell model

1 reference

7 January 2021

The enemy within: keeping self-reactive T cells at bay in the periphery

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7 January 2021

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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7 January 2021

Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance

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7 January 2021

Control of T-cell activation by CD4+ CD25+ suppressor T cells

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7 January 2021

CD4+ CD25+ suppressor T cells: more questions than answers

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7 January 2021

Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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7 January 2021

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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7 January 2021

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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7 January 2021

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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7 January 2021

Major histocompatibility complex class II-positive cortical epithelium mediates the selection of CD4(+)25(+) immunoregulatory T cells

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7 January 2021

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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7 January 2021

Origin of regulatory T cells with known specificity for antigen

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7 January 2021

Control of regulatory T cell development by the transcription factor Foxp3

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7 January 2021

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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7 January 2021

An essential role for Scurfin in CD4+CD25+ T regulatory cells

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7 January 2021

Several different cell surface molecules control negative selection of medullary thymocytes

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7 January 2021

Negative selection of CD4+CD8+ thymocytes by T cell receptor-induced apoptosis requires a costimulatory signal that can be provided by CD28

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7 January 2021

T cell receptor (TCR)-induced death of immature CD4+CD8+ thymocytes by two distinct mechanisms differing in their requirement for CD28 costimulation: implications for negative selection in the thymus

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7 January 2021

The B7-CD28 superfamily

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7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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7 January 2021

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

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7 January 2021

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-XL.

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7 January 2021

T-cell regulation by CD28 and CTLA-4.

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7 January 2021

Antigen compartmentation and T helper cell tolerance induction

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7 January 2021

Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling

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7 January 2021

T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif

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7 January 2021

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

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7 January 2021

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

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7 January 2021

CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2

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7 January 2021

Homeostasis of peripheral CD4+ T cells: IL-2R alpha and IL-2 shape a population of regulatory cells that controls CD4+ T cell numbers

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7 January 2021

Surface molecules that drive T cell development in vitro in the absence of thymic epithelium and in the absence of lineage-specific signals

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7 January 2021

Maturation versus death of developing double-positive thymocytes reflects competing effects on Bcl-2 expression and can be regulated by the intensity of CD28 costimulation

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7 January 2021

Asymmetric signaling requirements for thymocyte commitment to the CD4+ versus CD8+ T cell lineages: a new perspective on thymic commitment and selection

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7 January 2021

Regulation of Lck activity by CD4 and CD28 in the immunological synapse

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

Differential T cell costimulatory requirements in CD28-deficient mice

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7 January 2021

A point mutation in CD28 distinguishes proliferative signals from survival signals

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7 January 2021

Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

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7 January 2021

Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

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7 January 2021

Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation

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7 January 2021

Coreceptor reversal in the thymus: signaled CD4+8+ thymocytes initially terminate CD8 transcription even when differentiating into CD8+ T cells

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7 January 2021

bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes

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7 January 2021

Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptor

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7 January 2021

Identifiers

DOI

10.1038/NI1160

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Dimensions Publication ID

3 August 2017

1017234771

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