Functional screening of Alzheimer pathology genome-wide association signals in Drosophila (Q34560834)

3 August 2017

title

Functional screening of Alzheimer pathology genome-wide association signals in Drosophila (English)

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genome-wide association study

3 August 2017

main subject

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9

David A Bennett

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3 August 2017

11

Philip L De Jager

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3 August 2017

3

Lori B Chibnik

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3 August 2017

8

Julie A Schneider

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3 August 2017

Joshua M Shulman

1

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3 August 2017

Portia Chipendo

2

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3 August 2017

Cristin Aubin

4

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3 August 2017

Dong Tran

5

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3 August 2017

Brendan T Keenan

6

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3 August 2017

Patricia L Kramer

7

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3 August 2017

Mel B Feany

10

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3 August 2017

language of work or name

English

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publication date

3 February 2011

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American Journal of Human Genetics

3 August 2017

published in

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3 August 2017

volume

88

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3 August 2017

issue

2

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3 August 2017

page(s)

232-238

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Tau reduction prevents Abeta-induced defects in axonal transport.

3 August 2017

cites work

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Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

7 July 2018

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Intermediate phenotypes identify divergent pathways to Alzheimer's disease

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Alzheimer's disease: insights from Drosophila melanogaster models

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

7 July 2018

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

7 July 2018

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Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

7 July 2018

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Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles

7 July 2018

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Validating, augmenting and refining genome-wide association signals

7 July 2018

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FlyBase: enhancing Drosophila Gene Ontology annotations

7 July 2018

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Animal models of Alzheimer's disease and frontotemporal dementia

7 July 2018

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Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease

7 July 2018

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Vector and parameters for targeted transgenic RNA interference in Drosophila melanogaster

7 July 2018

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A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila

7 July 2018

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Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

7 July 2018

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Oxidative stress mediates tau-induced neurodegeneration in Drosophila

7 July 2018

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A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration

7 July 2018

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7 July 2018

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Biologically active molecules that reduce polyglutamine aggregation and toxicity

7 July 2018

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The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study

7 July 2018

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7 July 2018

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The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes

7 July 2018

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7 July 2018

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Apolipoprotein E epsilon4 allele, AD pathology, and the clinical expression of Alzheimer's disease

7 July 2018

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GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms

7 July 2018

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7 July 2018

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7 July 2018

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Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

7 July 2018

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7 July 2018

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7 July 2018

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Axon repulsion from the midline of the Drosophila CNS requires slit function.

7 July 2018

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Transgenic Drosophila expressing human amyloid precursor protein show gamma-secretase activity and a blistered-wing phenotype

7 July 2018

1 reference

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

7 July 2018

1 reference

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Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

Cytoskeleton proteins are modulators of mutant tau-induced neurodegeneration in Drosophila.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

The Rush Memory and Aging Project: study design and baseline characteristics of the study cohort

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

found in neurons, a third member of the Drosophila elav gene family, encodes a neuronal protein and interacts with elav

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3035702

10.1016/J.AJHG.2011.01.006

27 October 2018

Identifiers

DOI

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3 August 2017

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3 August 2017

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