Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity (Q34575855)

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English	Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity	scientific article

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scholarly article

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3 August 2017

Stable IgG-like bispecific antibodies directed toward the type I insulin-like growth factor receptor demonstrate enhanced ligand blockade and anti-tumor activity (English)

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3 August 2017

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Jianying Dong

1

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3 August 2017

Arlene Sereno

2

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3 August 2017

William B Snyder

3

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3 August 2017

Brian R Miller

4

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3 August 2017

Susan Tamraz

5

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3 August 2017

Adam Doern

6

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3 August 2017

Michael Favis

7

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3 August 2017

Xiufeng Wu

8

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3 August 2017

Hon Tran

9

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3 August 2017

Emma Langley

10

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3 August 2017

Ingrid Joseph

11

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3 August 2017

Antonio Boccia

12

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3 August 2017

Rebecca Kelly

13

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3 August 2017

Kathleen Wortham

14

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3 August 2017

Qin Wang

15

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3 August 2017

Lisa Berquist

16

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3 August 2017

Flora Huang

17

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3 August 2017

Sharon X Gao

18

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3 August 2017

Ying Zhang

19

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3 August 2017

Alexey Lugovskoy

20

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3 August 2017

Shelly Martin

21

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3 August 2017

Heather Gouvis

22

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3 August 2017

Steven Berkowitz

23

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3 August 2017

Gisela Chiang

24

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3 August 2017

Mitchell Reff

25

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3 August 2017

Scott M Glaser

26

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3 August 2017

Kandasamy Hariharan

27

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3 August 2017

Stephen J Demarest

28

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3 August 2017

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publication date

1 December 2010

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3 August 2017

Journal of Biological Chemistry

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3 August 2017

286

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3 August 2017

6

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3 August 2017

4703-4717

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3 August 2017

Stability engineering of scFvs for the development of bispecific and multivalent antibodies

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Alternative antibody formats.

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Anti-tumor activity of stability-engineered IgG-like bispecific antibodies targeting TRAIL-R2 and LTbetaR.

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Characterization of inhibitory anti-insulin-like growth factor receptor antibodies with different epitope specificity and ligand-blocking properties: implications for mechanism of action in vivo

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Insulin and insulin-like growth factor signalling in neoplasia

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Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro

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Comprehensive analysis of the factors contributing to the stability and solubility of autonomous human VH domains

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Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action

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The design and characterization of oligospecific antibodies for simultaneous targeting of multiple disease mediators

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Bispecific antibodies: molecules that enable novel therapeutic strategies

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Identifiers

10.1074/JBC.M110.184317

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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