Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats (Q34582334)

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English	Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

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cannabinoid receptor

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5

object named as

Debra I Diz

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Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Chris L Schaich

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Europe PubMed Central

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3 August 2017

Hossam A Shaltout

2

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Europe PubMed Central

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3 August 2017

K Bridget Brosnihan

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Europe PubMed Central

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3 August 2017

Allyn C Howlett

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3 August 2017

publication date

28 August 2014

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3 August 2017

Physiological Reports

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Europe PubMed Central

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3 August 2017

2

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Europe PubMed Central

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3 August 2017

8

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Europe PubMed Central

PubMed publication ID

3 August 2017

Chronic blockade of angiotensin AT₁ receptors improves cardinal symptoms of metabolic syndrome in diet-induced obesity in rats

1 reference

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7 July 2018

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

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Heart disease and stroke statistics--2014 update: a report from the American Heart Association

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7 July 2018

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides

1 reference

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7 July 2018

Activation of the sympathetic nervous system mediates hypophagic and anxiety-like effects of CB₁ receptor blockade

1 reference

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7 July 2018

Renin-angiotensin system: upgrade of recent knowledge and perspectives

1 reference

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7 July 2018

Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors.

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7 July 2018

CB1 receptor antagonists: new discoveries leading to new perspectives

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7 July 2018

Effects of Chronic Antagonism of Endocannabinoid-1 Receptors on Glucose Tolerance and Insulin Action in Skeletal Muscles of Lean and Obese Zucker Rats

1 reference

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7 July 2018

Regulation of endocannabinoid release by G proteins: a paracrine mechanism of G protein-coupled receptor action.

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7 July 2018

AT1R-CB₁R heteromerization reveals a new mechanism for the pathogenic properties of angiotensin II.

1 reference

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7 July 2018

Peripheral effects of the endocannabinoid system in energy homeostasis: adipose tissue, liver and skeletal muscle

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7 July 2018

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Adenoviral inhibition of AT1a receptors in the paraventricular nucleus inhibits acute increases in mean arterial blood pressure in the rat

1 reference

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7 July 2018

CB1 receptor inhibition leads to decreased vascular AT1 receptor expression, inhibition of oxidative stress and improved endothelial function

1 reference

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7 July 2018

Leptin impairs cardiovagal baroreflex function at the level of the solitary tract nucleus

1 reference

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7 July 2018

Effects of chronic treatment with the CB1 antagonist, rimonabant on the blood pressure, and vascular reactivity of obese Zucker rats

1 reference

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7 July 2018

Paracrine transactivation of the CB1 cannabinoid receptor by AT1 angiotensin and other Gq/11 protein-coupled receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Spontaneous baroreflex measures are unable to detect age-related impairments in cardiac baroreflex function during dynamic exercise in humans

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Acute hypertension reveals depressor and vasodilator effects of cannabinoids in conscious rats

1 reference

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Peripherally administered angiotensin II AT1 receptor antagonists are anti-stress compounds in vivo

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7 July 2018

Metabolic effects of an AT1-receptor blockade combined with HCTZ in cardiac risk patients: a non interventional study in primary care

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Blood pressure lowering effects of rimonabant in obesity-related hypertension.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Effect of rimonabant on blood pressure in overweight/obese patients with/without co-morbidities: analysis of pooled RIO study results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Cannabinoid receptor signaling directly inhibits thermogenesis and alters expression of adiponectin and visfatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Adiponectin, an adipocyte-derived protein.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Endocannabinoids acting at cannabinoid-1 receptors regulate cardiovascular function in hypertension

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

The role of the novel adipocyte-derived hormone adiponectin in human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Leptin-regulated endocannabinoids are involved in maintaining food intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

1 reference

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Cardiovascular effects of anandamide in anesthetized and conscious normotensive and hypertensive rats

1 reference

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Insulin microinjection into the nucleus tractus solitarii of the rat attenuates the baroreceptor reflex

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7 July 2018

Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects

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7 July 2018

Role of tissue renin in the pathophysiology of hypertension in TGR(mREN2)27 rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

7 July 2018

Cannabinoid receptor 1 inhibition improves cardiac function and remodelling after myocardial infarction and in experimental metabolic syndrome

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

ACE inhibition and AT1 receptor blockade prevent fatty liver and fibrosis in obese Zucker rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

Cannabinoids inhibit noradrenergic and purinergic sympathetic cotransmission in the rat isolated mesenteric arterial bed.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

The cannabinoid CB1 receptor inverse agonist, rimonabant, modifies body weight and adiponectin function in diet-induced obese rats as a consequence of reduced food intake

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

Selective angiotensin II receptor antagonism enhances whole-body insulin sensitivity and muscle glucose transport in hypertensive TG(mREN2)27 rats

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4246581

27 October 2018

Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia

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27 October 2018

Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems

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27 October 2018

Mechanism of fatty acids induced suppression of cardiovascular reflexes in rats.

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27 October 2018

Defective insulin signaling in skeletal muscle of the hypertensive TG(mREN2)27 rat.

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27 October 2018

The anti-obesity effect of rimonabant is associated with an improved serum lipid profile

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27 October 2018

Estrogen or the AT1 antagonist olmesartan reverses the development of profound hypertension in the congenic mRen2. Lewis rat.

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27 October 2018

Preferential effects of the cannabinoid CB1 receptor antagonist, SR 141716, on food intake and body weight gain of obese (fa/fa) compared to lean Zucker rats.

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27 October 2018

Anti-obesity effect of SR141716, a CB1 receptor antagonist, in diet-induced obese mice

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27 October 2018

Mesenteric vasodilation mediated by endothelial anandamide receptors

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27 October 2018

Lipid disorders in obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood pressure and sympathetic activity in spontaneously hypertensive rats during food restriction

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypercholesterolemia is associated with enhanced angiotensin AT1-receptor expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of arterial hypertension in obese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/25168868

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.14814/PHY2.12108

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Europe PubMed Central

PubMed publication ID

3 August 2017

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24 November 2022

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PMC publication ID

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Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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