Post-translational modifications regulate the ticking of the circadian clock. (Q34605395)

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24 December 2019

review article

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title

Post-translational modifications regulate the ticking of the circadian clock (English)

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24 December 2019

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2

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24 December 2019

author name string

Monica Gallego

series ordinal

1

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24 December 2019

publication date

1 February 2007

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Nature Reviews Molecular Cell Biology

24 December 2019

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17245414%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

volume

8

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24 December 2019

issue

2

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24 December 2019

page(s)

139-148

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The molecular clock mediates leptin-regulated bone formation.

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PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription

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Proteins in the Neurospora circadian clockworks

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CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loop

31 March 2020

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Phosphorylation-dependent maturation of Neurospora circadian clock protein from a nuclear repressor toward a cytoplasmic activator

31 March 2020

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Molecular mechanism of light responses in Neurospora: from light-induced transcription to photoadaptation

31 March 2020

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Phosphorylation of the Neurospora clock protein FREQUENCY determines its degradation rate and strongly influences the period length of the circadian clock

31 March 2020

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FWD1-mediated degradation of FREQUENCY in Neurospora establishes a conserved mechanism for circadian clock regulation

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Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.

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Role of molecular oscillations in generating behavioral rhythms in Drosophila.

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Constitutive expression of the Period1 gene impairs behavioral and molecular circadian rhythms

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Does mPER2 protein oscillate without its coding mRNA cycling?: post-transcriptional regulation by cell clock

31 March 2020

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The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase Iepsilon

31 March 2020

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An opposite role for tau in circadian rhythms revealed by mathematical modeling

31 March 2020

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Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1.

31 March 2020

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Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK protein

31 March 2020

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The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iepsilon

31 March 2020

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double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation

31 March 2020

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Isolation and characterization of human casein kinase I epsilon (CKI), a novel member of the CKI gene family

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Casein kinase I: from obscurity to center stage

31 March 2020

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Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau.

31 March 2020

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Familial advanced sleep-phase syndrome: A short-period circadian rhythm variant in humans

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An hPer2 phosphorylation site mutation in familial advanced sleep phase syndrome

31 March 2020

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Functional consequences of a CKIdelta mutation causing familial advanced sleep phase syndrome

31 March 2020

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A PEST-like element in FREQUENCY determines the length of the circadian period in Neurospora crassa

31 March 2020

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One-thousand-and-one substrates of protein kinase CK2?

31 March 2020

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Casein kinase 2, circadian clocks, and the flight from mutagenic light

31 March 2020

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A role for casein kinase 2alpha in the Drosophila circadian clock

31 March 2020

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In vivo circadian function of casein kinase 2 phosphorylation sites in Drosophila PERIOD.

31 March 2020

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A role for CK2 in the Drosophila circadian oscillator

31 March 2020

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Regulation of the Neurospora circadian clock by casein kinase II

31 March 2020

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Phosphorylation of FREQUENCY protein by casein kinase II is necessary for the function of the Neurospora circadian clock

31 March 2020

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A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock

31 March 2020

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A role for glycogen synthase kinase-3beta in the mammalian circadian clock

31 March 2020

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Nuclear receptor Rev-erbalpha is a critical lithium-sensitive component of the circadian clock

31 March 2020

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Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta.

31 March 2020

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Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription.

31 March 2020

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The p42/44 mitogen-activated protein kinase pathway couples photic input to circadian clock entrainment

31 March 2020

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cGMP-dependent protein kinase II modulates mPer1 and mPer2 gene induction and influences phase shifts of the circadian clock

31 March 2020

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Protein kinase G type II is required for night-to-day progression of the mammalian circadian clock.

31 March 2020

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31 March 2020

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PP2A: the expected tumor suppressor

31 March 2020

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Functional diversity of protein phosphatase-1, a cellular economizer and reset button

31 March 2020

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Distinct roles for PP1 and PP2A in the Neurospora circadian clock

31 March 2020

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Posttranslational regulation of Drosophila PERIOD protein by protein phosphatase 2A.

31 March 2020

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Posttranslational regulation of the mammalian circadian clock by cryptochrome and protein phosphatase 5.

31 March 2020

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Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle

31 March 2020

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Autoinhibition of casein kinase I epsilon (CKI epsilon) is relieved by protein phosphatases and limited proteolysis

31 March 2020

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JETLAG resets the Drosophila circadian clock by promoting light-induced degradation of TIMELESS.

31 March 2020

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A role for the proteasome in the light response of the timeless clock protein.

31 March 2020

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Cloning and characterization of rat casein kinase 1epsilon

31 March 2020

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Phosphorylation and destabilization of human period I clock protein by human casein kinase I epsilon

31 March 2020

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Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

31 March 2020

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Human casein kinase Idelta phosphorylation of human circadian clock proteins period 1 and 2.

31 March 2020

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31 March 2020

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Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts

31 March 2020

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SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein

31 March 2020

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Protein phosphatase 1 regulates the stability of the circadian protein PER2.

31 March 2020

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31 March 2020

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SCF-mediated protein degradation and cell cycle control

31 March 2020

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The F-box protein slimb controls the levels of clock proteins period and timeless

31 March 2020

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Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.

31 March 2020

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Photic signaling by cryptochrome in the Drosophila circadian system

31 March 2020

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A detailed predictive model of the mammalian circadian clock

31 March 2020

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Model based conjectures on mammalian clock controversies.

31 March 2020

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Circadian clock control by SUMOylation of BMAL1.

31 March 2020

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The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein period

31 March 2020

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The doubletime and CKII kinases collaborate to potentiate Drosophila PER transcriptional repressor activity

31 March 2020

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mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop

31 March 2020

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Identification of mPer1 phosphorylation sites responsible for the nuclear entry

31 March 2020

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Regulation of nuclear entry of the Drosophila clock proteins period and timeless.

31 March 2020

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Sequential nuclear accumulation of the clock proteins period and timeless in the pacemaker neurons of Drosophila melanogaster.

31 March 2020

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PER-TIM interactions in living Drosophila cells: an interval timer for the circadian clock

31 March 2020

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Physiology. Running a clock requires quality time together.

31 March 2020

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Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro

31 March 2020

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Mechanism of regulation of casein kinase I activity by group I metabotropic glutamate receptors

31 March 2020

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Regulation of casein kinase I epsilon activity by Wnt signaling

31 March 2020

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Molecular genetics of timing in intrinsic circadian rhythm sleep disorders

31 March 2020

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The circadian basis of winter depression

31 March 2020

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Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome

31 March 2020

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A missense variation in human casein kinase I epsilon gene that induces functional alteration and shows an inverse association with circadian rhythm sleep disorders

31 March 2020

1 reference

Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factor

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NRM2106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17245414%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 December 2019

1003348925

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