An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans. (Q34602710)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

Phosphatidylinositol 3-kinase age-1 CELE_B0334.8

10 November 2019

main subject

Caenorhabditis elegans

0 references

1 reference

GOA release 2020-03-11

1 reference

2

G Ruvkun

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

author name string

H A Tissenbaum

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

language of work or name

English

0 references

publication date

1 February 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

number of pages

15

1 reference

inferred from page(s)

published in

Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

volume

148

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

page(s)

703-717

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

10 November 2019

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIM homeobox gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Control of C. elegans larval development by neuronal expression of a TGF-beta homolog

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Chemosensory neurons function in parallel to mediate a pheromone response in C. elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Genetic analysis of the roles of daf-28 and age-1 in regulating Caenorhabditis elegans dauer formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Not all Shc's roads lead to Ras

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Do changes in chromosomes cause aging?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Oxidative stress, caloric restriction, and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Determination of life-span in Caenorhabditis elegans by four clock genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Targeted disruption of the insulin receptor gene in the mouse results in neonatal lethality

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

A mutation in the age-1 gene in Caenorhabditis elegans lengthens life and reduces hermaphrodite fertility

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

The age-1 and daf-2 genes function in a common pathway to control the lifespan of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Ponce d'elegans: genetic quest for the fountain of youth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Aging and resistance to oxidative damage in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Oxidative stress and ageing in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Evidence for parallel processing of sensory information controlling dauer formation in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

A C. elegans mutant that lives twice as long as wild type

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Chemosensory regulation of development in C. elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Mutation in the silencing gene S/R4 can delay aging in S. cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Genes that regulate both development and longevity in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Homozygous deletion of the human insulin receptor gene results in leprechaunism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

The gerontogenes age-1 and daf-2 determine metabolic rate potential in aging Caenorhabditis elegans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Interacting genes in nematode dauer larva formation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

The Caenorhabditis elegans dauer larva: developmental effects of pheromone, food, and temperature

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

A method for the isolation of longevity mutants in the nematode Caenorhabditis elegans and initial results

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

The genetics of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Three mutants that extend both mean and maximum life span of the nematode, Caenorhabditis elegans, define the age-1 gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Mutant sensory cilia in the nematode Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Retardation of the Aging Processes in Rats by Food Restriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Genetic analysis of chemosensory control of dauer formation in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Production of sperm reduces nematode lifespan

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Non-ageing developmental variant of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

The dauerlarva, a post-embryonic developmental variant of the nematode Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Evidence for a dystrophin missense mutation as a cause of X-linked dilated cardiomyopathy.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Longevity in Caenorhabditis elegans reduced by mating but not gamete production

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Homozygous nonsense mutation in the insulin receptor gene in infant with leprechaunism.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1459840

Critical periods in the development of the Caenorhabditis elegans dauer larva

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9504918

12 December 2020

inferred from PubMed ID database lookup

More is not better: brood size and population growth in a self-fertilizing nematode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9504918

12 December 2020

inferred from PubMed ID database lookup

Early neonatal death in mice homozygous for a null allele of the insulin receptor gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9504918

12 December 2020

inferred from PubMed ID database lookup

Identifiers

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9504918%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

9504918

1 reference