The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity (Q34623161)

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English	The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

3 August 2017

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Europe PubMed Central

The pharmacology of Ro 64-6198, a systemically active, nonpeptide NOP receptor (opiate receptor-like 1, ORL-1) agonist with diverse preclinical therapeutic activity (English)

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Europe PubMed Central

PubMed publication ID

3 August 2017

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based on heuristic

inferred from title

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

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James R Shoblock

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PubMed publication ID

3 August 2017

publication date

1 January 2007

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Europe PubMed Central

PubMed publication ID

3 August 2017

CNS Neuroscience & Therapeutics

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

13

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

107-136

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

Up-regulation of ORL-1 receptors in spinal tissue of allodynic rats after sciatic nerve injury.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Pharmacological characterization of the nociceptin receptor mediating hyperalgesia in the mouse tail withdrawal assay

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Effects of nociceptin (13-17) in pain modulation at supraspinal level in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Drugs to suppress cough

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Nociceptin/orphanin FQ and drugs of abuse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Effect of nociceptin/orphanin FQ on the rewarding properties of morphine.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Use of the elevated plus maze in the search for novel anxiolytic agents

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Nociceptin/orphanin FQ regulates neuroendocrine function of the limbic-hypothalamic-pituitary-adrenal axis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Central injections of nocistatin or its C-terminal hexapeptide exert anxiogenic-like effect on behaviour of mice in the plus-maze test

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ, a novel neuropeptide with anti-stress-like activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Influence of the selective ORL1 receptor agonist, Ro64-6198, on rodent neurological function.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

A combined pharmacological and genetic approach to investigate the role of orphanin FQ in learning and memory.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ acts as an anxiolytic to attenuate behavioral responses to stress

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

A synthetic agonist at the orphanin FQ/nociceptin receptor ORL1: anxiolytic profile in the rat.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

The NOP (ORL1) receptor antagonist Compound B stimulates mesolimbic dopamine release and is rewarding in mice by a non-NOP-receptor-mediated mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Targeted disruption of the orphanin FQ/nociceptin gene increases stress susceptibility and impairs stress adaptation in mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Is the nociceptin (NOP) receptor involved in attenuation of the expression of sensitization to morphine-induced hyperlocomotion in mice?

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ/nociceptin but not Ro 65-6570 inhibits the expression of cocaine-induced conditioned place preference

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Acquisition, expression, and reinstatement of ethanol-induced conditioned place preference in mice: effects of opioid receptor-like 1 receptor agonists and naloxone

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Evidence in locomotion test for the functional heterogeneity of ORL-1 receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Enhancement of spatial attention in nociceptin/orphanin FQ receptor-knockout mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Partial agonist behaviour depends upon the level of nociceptin/orphanin FQ receptor expression: studies using the ecdysone-inducible mammalian expression system.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

The nociceptin (ORL1) receptor: molecular cloning and functional architecture

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ is a functional anti-opioid peptide.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ/nociceptin blocks acquisition of morphine place preference

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Comparison of the effects of [Phe1psi(CH2-NH)Gly2]nociceptin(1-13)NH2 in rat brain, rat vas deferens and CHO cells expressing recombinant human nociceptin receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Effects of maternal separation on brain nociceptin/orphanin FQ peptide levels in male Wistar rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Effects of Ro 64-6198 in nociceptin/orphanin FQ-sensitive isolated tissues

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

High-affinity, non-peptide agonists for the ORL1 (orphanin FQ/nociceptin) receptor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Pharmacological validation of a new animal model of alcoholism.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Nonphotic entrainment of the circadian body temperature rhythm by the selective ORL1 receptor agonist W-212393 in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

pH-dependency of basic ligand binding to alpha 1-acid glycoprotein (orosomucoid)

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Characterization of the nociceptin receptor (ORL-1) agonist, Ro64-6198, in tests of anxiety across multiple species

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Heterodimerization of opioid receptor-like 1 and mu-opioid receptors impairs the potency of micro receptor agonist

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Synthesis of (1S,3aS)-8-(2,3,3a,4,5, 6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4. 5]decan-4-one, a potent and selective orphanin FQ (OFQ) receptor agonist with anxiolytic-like properties

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Orphanin FQ/nociceptin blocks methamphetamine place preference in rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

In vitro characterization of J-113397, a non-peptide nociceptin/orphanin FQ receptor antagonist

1 reference

https://api.crossref.org/works/10.1111%2FJ.1527-3458.2007.00007.X

21 January 2018

Strain-dependent effects of supraspinal orphanin FQ/nociceptin on thermal nociceptive sensitivity in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolic fate of nociceptin/orphanin FQ in the rat spinal cord and biological activity of its released fragment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8-acenaphthen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as orphanin FQ receptor agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin (1 - 7) antagonizes nociceptin-induced hyperalgesia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that N-terminal fragments of nociceptin modulate nociceptin-induced scratching, biting and licking in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORL1 receptor ligands: structure-activity relationships of 8-cycloalkyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-ones

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin prevents stress-induced ethanol- but not cocaine-seeking behavior in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin differentially affects morphine-induced dopamine release from the nucleus accumbens and nucleus caudate in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin inhibits cough in the guinea-pig by activation of ORL(1) receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological characterization of the novel nonpeptide orphanin FQ/nociceptin receptor agonist Ro 64-6198: rapid and reversible desensitization of the ORL1 receptor in vitro and lack of tolerance in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pronociceptive effects of nociceptin/orphanin FQ (13-17) at peripheral and spinal level in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in brain content of nociceptin/orphanin FQ and endomorphin 2 in a rat model of neuropathic pain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ into the rat periaqueductal gray decreases the withdrawal latency to heat and loading, an effect reversed by (Nphe(1))nociceptin(1-13)NH(2).

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological profile of nociceptin/orphanin FQ receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The orphanin receptor agonist RO 64-6198 does not induce place conditioning in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversal of stress- and CRF-induced anorexia in rats by the synthetic nociceptin/orphanin FQ receptor agonist, Ro 64-6198.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterisation of the non-peptide nociceptin receptor agonist, Ro64-6198 in Chinese hamster ovary cells expressing recombinant human nociceptin receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ and related peptides reduce the increase in plasma corticosterone elicited in mice by an intracerebroventricular injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ content is decreased in forebrain neurones during acute stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

UFP-101, a high affinity antagonist for the nociceptin/orphanin FQ receptor: radioligand and GTPgamma(35)S binding studies.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-peptidergic OP4 receptor agonist inhibits morphine antinociception but does not influence morphine dependence

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin inhibits acquisition of amphetamine-induced place preference and sensitization to stereotypy in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The rostral ventromedial medulla mediates the facilitatory effect of microinjected orphanin FQ in the periaqueductal gray on spinal nociceptive transmission in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of environmental housing conditions on the emotional responses of mice deficient for nociceptin/orphanin FQ peptide precursor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ increases anxiety-related behavior and circulating levels of corticosterone during neophobic tests of anxiety.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral and endocrine changes following antisense oligonucleotide-induced reduction in the rat NOP receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Central administration of nociceptin/orphanin FQ blocks the acquisition of conditioned place preference to morphine and cocaine, but not conditioned place aversion to naloxone in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADME evaluation in drug discovery. 3. Modeling blood-brain barrier partitioning using simple molecular descriptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-regulated internalization of the opioid receptor-like 1: a confocal study

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of nociceptin on the exploratory behavior of mice in the hole-board test

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modelling studies on the ORL1-receptor and ORL1-agonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence of substance P(1-7) in the metabolism of substance P and its antinociceptive activity at the mouse spinal cord level.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antitussive profile of the NOP agonist Ro-64-6198 in the guinea pig.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The opioid receptor like-1 receptor agonist Ro 64-6198 (1S,3aS-8-2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one) produces a discriminative stimulus in rats distinct from that of a mu, kappa, and delta opioid rece

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ro 64-6198 [(1S,3aS)-8-(2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one] acts differently from nociceptin/orphanin FQ in rat periaqueductal gray slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ADME evaluation in drug discovery. 5. Correlation of Caco-2 permeation with simple molecular properties.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of ORL1 mRNA in some brain nuclei in neuropathic pain rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of a systemically active ORL-1 agonist, Ro 64-6198, on the acquisition, expression, extinction, and reinstatement of morphine conditioned place preference

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spinal and local peripheral antiallodynic activity of Ro64-6198 in neuropathic pain in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral buspirone causes a shift in the dose-response curve between the elevated-plus maze and Vogel conflict tests in Long-Evans rats: relation of brain levels of buspirone and 1-PP to anxiolytic action

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan psychosis, dependence and physical withdrawal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small-molecule agonists and antagonists of the opioid receptor-like receptor (ORL1, NOP): ligand-based analysis of structural factors influencing intrinsic activity at NOP

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo pharmacological characterization of the nociceptin/orphanin FQ receptor ligand Ac-RYYRIK-ol.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic-like effects of nociceptin/orphanin FQ in the elevated plus maze and in the conditioned defensive burying test in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nociceptin receptor antagonist [Nphe1,Arg14,Lys15]nociceptin/orphanin FQ-NH2 blocks the stimulatory effects of nociceptin/orphanin FQ on the HPA axis in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coupling of ORL1 (NOP) receptor to G proteins is decreased in the nucleus accumbens of anxious relative to non-anxious mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nociceptin/orphanin FQ receptor agonist Ro 64-6198 reduces alcohol self-administration and prevents relapse-like alcohol drinking

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A combined marble burying-locomotor activity test in mice: a practical screening test with sensitivity to different classes of anxiolytics and antidepressants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug binding to human alpha-1-acid glycoprotein in health and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Orphanin FQ: a neuropeptide that activates an opioidlike G protein-coupled receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for orphanin FQ/nociceptin receptor heterogeneity in mouse brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fentanyl metabolism by human hepatic and intestinal cytochrome P450 3A4: implications for interindividual variability in disposition, efficacy, and drug interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin fails to affect heroin self-administration in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin-induced apparent hyperalgesia in mice as a result of the prevention of opioid autoanalgesic mechanisms triggered by the stress of an intracerebroventricular injection

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nociceptin (ORL-1) and mu-opioid receptors mediate mitogen-activated protein kinase activation in CHO cells through a Gi-coupled signaling pathway: evidence for distinct mechanisms of agonist-mediated desensitization

1 reference

https://pubmed.ncbi.nlm.nih.gov/17461893

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1527-3458.2007.00007.X

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6494153&resulttype=core&format=json

14 May 2020

ResearchGate publication ID

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