Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila (Q34632518)

3 August 2017

title

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila (English)

1 reference

3 August 2017

main subject

Caenorhabditis elegans

0 references

Drosophila

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Sirtuin 1 Dmel_CG5216

1 reference

GOA release 2020-03-11

1 reference

1 reference

22

Linda Partridge

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George L Sutphin

George L Sutphin

8

0 references

Filipe Cabreiro

Filipe Cabreiro

Rafael P Vázquez-Manrique

3

0 references

Rafael P Vazquez-Manrique

11

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Matthew D Piper

Matthew D Piper

6

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David Gems

David Gems

23

0 references

Matt Kaeberlein

Matt Kaeberlein

20

0 references

Catherine Au

Catherine Au

14

1 reference

ORCID Public Data File 2021

author name string

Camilla Burnett

1

1 reference

3 August 2017

Sara Valentini

2

1 reference

3 August 2017

Martin Goss

4

1 reference

3 August 2017

Milán Somogyvári

5

1 reference

3 August 2017

Matthew Hoddinott

7

1 reference

3 August 2017

Vid Leko

9

1 reference

3 August 2017

Joshua J McElwee

10

1 reference

3 August 2017

Anne-Marie Orfila

12

1 reference

3 August 2017

Daniel Ackerman

13

1 reference

3 August 2017

Giovanna Vinti

15

1 reference

3 August 2017

Michèle Riesen

16

1 reference

3 August 2017

Ken Howard

17

1 reference

3 August 2017

Christian Neri

18

1 reference

3 August 2017

Antonio Bedalov

19

1 reference

3 August 2017

Csaba Soti

21

1 reference

3 August 2017

language of work or name

English

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publication date

21 September 2011

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3 August 2017

1 reference

3 August 2017

volume

477

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3 August 2017

issue

7365

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3 August 2017

page(s)

482-485

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Lessons on longevity from budding yeast

3 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

7 July 2018

The genetics of ageing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Mammalian sirtuins: biological insights and disease relevance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Resveratrol is not a direct activator of SIRT1 enzyme activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Sirtuins in aging and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Aging and survival: the genetics of life span extension by dietary restriction.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Clustering of genetically defined allele classes in the Caenorhabditis elegans DAF-2 insulin/IGF-1 receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Resveratrol rescues mutant polyglutamine cytotoxicity in nematode and mammalian neurons.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Mechanism of human SIRT1 activation by resveratrol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Substrate-specific activation of sirtuins by resveratrol

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Quantitative assays for characterization of the Sir2 family of NAD(+)-dependent deacetylases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Systematic functional analysis of the Caenorhabditis elegans genome using RNAi

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Regulation of lifespan by sensory perception in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Two pleiotropic classes of daf-2 mutation affect larval arrest, adult behavior, reproduction and longevity in Caenorhabditis elegans.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

The genetics of Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188402

Benchmarks for ageing studies

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21938067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A mid-life crisis for aging theory

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21938067

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10296

1 reference

Dimensions Publication ID

3 August 2017

0 references

1 reference

3 August 2017

1 reference