The role of biotransformation in chemical-induced liver injury (Q34663568)

3 August 2017

title

The role of biotransformation in chemical-induced liver injury (English)

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3 August 2017

J R Mitchell

1

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3 August 2017

W R Snodgrass

series ordinal

2

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3 August 2017

J R Gillette

series ordinal

3

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3 August 2017

publication date

1 June 1976

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Environmental Health Perspectives

3 August 2017

published in

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3 August 2017

volume

15

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3 August 2017

page(s)

27-38

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Biochemical studies of toxic agents. 11. The occurrence of premercapturic acids

3 August 2017

cites work

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Studies in detoxication. 51. The determination of catechols in urine, and the formation of catechols in rabbits receiving halogenobenzenes and other compounds; dihydroxylation in vivo

7 July 2018

1 reference

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Liver necrosis from paracetamol

7 July 2018

1 reference

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Mechanisms of chemical carcinogenesis: nature of proximate carcinogens and interactions with macromolecules

7 July 2018

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Carcinogenesis by chemicals: an overview--G. H. A. Clowes memorial lecture

7 July 2018

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Carcinogenic nitroso compounds

7 July 2018

1 reference

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Carbon tetrachloride hepatotoxicity

7 July 2018

1 reference

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Species differences in hepatic glutathione depletion, covalent binding and hepatic necrosis after acetaminophen.

7 July 2018

1 reference

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Arene oxides: a new aspect of drug metabolism

7 July 2018

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Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite

7 July 2018

1 reference

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Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

7 July 2018

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Centrolobular hepatic necrosis related to covalent binding of metabolites of halogenated aromatic hydrocarbons

7 July 2018

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Acetaminophen-induced hepatic necrosis. VI. Metabolic disposition of toxic and nontoxic doses of acetaminophen.

7 July 2018

1 reference

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Acetaminophen-induced hepatic necrosis. V. Correlation of hepatic necrosis, covalent binding and glutathione depletion in hamsters.

7 July 2018

1 reference

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Possible mechanism of liver necrosis caused by aromatic organic compounds

7 July 2018

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Isoniazid-associated hepatitis in 114 patients

7 July 2018

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The effect of diet on the toxicity of paracetamol and the safety of paracetamol-methionine mixtures

7 July 2018

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Acetylation rates and monthly liver function tests during one year of isoniazid preventive therapy

7 July 2018

1 reference

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Isoniazid liver injury: clinical spectrum, pathology, and probable pathogenesis

7 July 2018

1 reference

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Metabolism and binding of aromatic hydrocarbons in the lung. Relationship to experimental bronchiolar necrosis

7 July 2018

1 reference

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Drug metabolism as a cause of drug toxicity

26 October 2018

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12 December 2020

Relationship of alcohol metabolism to the potentiation of CCl 4 hepatotoxicity induced by aliphatic alcohols

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro

1 reference

12 December 2020

Acetaminophen-induced hepatic injury: protective role of glutathione in man and rationale for therapy.

1 reference

12 December 2020

Hepatic necrosis caused by furosemide

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12 December 2020

Role of detoxifying enzymes in bromobenzene-induced liver necrosis

1 reference

12 December 2020

Acetaminophen-induced hepatic necrosis. I. Role of drug metabolism

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12 December 2020

Increased incidence of isoniazid hepatitis in rapid acetylators: possible relation to hydrazine metabolites

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12 December 2020

Progress in hepatology. Metabolic activation of drugs to toxic substances

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12 December 2020

Identifiers

DOI

10.1289/EHP.761527

1 reference

3 August 2017

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3 August 2017

1 reference