Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins (Q34680467)

3 August 2017

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Pharmacogenetic Foundations of Therapeutic Efficacy and Adverse Events of Statins (English)

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3 August 2017

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mitochondrial protein

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Romano Danesi

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9 June 2020

author name string

Elena Arrigoni

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9 June 2020

Leonardo Fidilio

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Stefano Fogli

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9 June 2020

Antonello Di Paolo

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9 June 2020

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English

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publication date

6 January 2017

16 references

International Journal of Molecular Sciences

3 August 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067828%20AND%20SRC:MED&resulttype=core&format=json

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9 June 2020

issue

1

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Creative Commons Attribution

9 June 2020

copyright license

15 references

19 June 2019

30 June 2019

8 September 2019

14 September 2019

28 September 2019

2 October 2019

18 November 2019

28 November 2019

14 December 2019

15 December 2019

18 December 2019

21 July 2020

2 November 2020

16 December 2020

30 January 2021

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Inhibition of Aberrant MicroRNA-133a Expression in Endothelial Cells by Statin Prevents Endothelial Dysfunction by Targeting GTP Cyclohydrolase 1 in Vivo

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Genetic and Non-Genetic Determinants of the Pharmacological Activity of Statins.

7 July 2018

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7 July 2018

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Pharmacogenomics of Rosuvastatin: A Glocal (Global+Local) African Perspective and Expert Review on a Statin Drug

7 July 2018

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7 July 2018

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Atorvastatin attenuation of ABCB1 expression is mediated by microRNA miR-491-3p in Caco-2 cells

7 July 2018

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7 July 2018

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Pitavastatin Differentially Modulates MicroRNA-Associated Cholesterol Transport Proteins in Macrophages

7 July 2018

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Comparison of the Risk of Gastrointestinal Bleeding among Different Statin Exposures with Concomitant Administration of Warfarin: Electronic Health Record-Based Retrospective Cohort Study

7 July 2018

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Effects of Pitavastatin on Lipid Profiles in HIV-Infected Patients with Dyslipidemia and Receiving Atazanavir/Ritonavir: A Randomized, Double-Blind, Crossover Study

7 July 2018

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Effect of vildagliptin and pravastatin combination on cholesterol efflux in adipocytes

7 July 2018

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Modulation of microRNA Expression in Subjects with Metabolic Syndrome and Decrease of Cholesterol Efflux from Macrophages via microRNA-33-Mediated Attenuation of ATP-Binding Cassette Transporter A1 Expression by Statins

7 July 2018

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Pharmacogenetics of Lipid-Lowering Agents: Precision or Indecision Medicine?

7 July 2018

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The safety of ezetimibe and simvastatin combination for the treatment of hypercholesterolemia

7 July 2018

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Risks of Adverse Events Following Coprescription of Statins and Calcium Channel Blockers: A Nationwide Population-Based Study

7 July 2018

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Seventeen years of statin pharmacogenetics: a systematic review

7 July 2018

1 reference

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Drug Interactions with the Direct-Acting Antiviral Combination of Ombitasvir and Paritaprevir-Ritonavir

7 July 2018

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ABCB1 C3435T polymorphism and the lipid-lowering response in hypercholesterolemic patients on statins: a meta-analysis

7 July 2018

1 reference

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Association Between SLCO1B1 Gene T521C Polymorphism and Statin-Related Myopathy Risk: A Meta-Analysis of Case-Control Studies

7 July 2018

1 reference

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Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid

7 July 2018

1 reference

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Physiologically based pharmacokinetic modeling of disposition and drug-drug interactions for atorvastatin and its metabolites

7 July 2018

1 reference

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Marked Alteration of Rosuvastatin Pharmacokinetics in Healthy Chinese with ABCG2 34G>A and 421C>A Homozygote or Compound Heterozygote

7 July 2018

1 reference

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Drug-drug interactions that interfere with statin metabolism

7 July 2018

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7 July 2018

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Role of microRNAs 221/222 on statin induced nitric oxide release in human endothelial cells

7 July 2018

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Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

7 July 2018

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HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

7 July 2018

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Possible association of ABCB1:c.3435T>C polymorphism with high-density-lipoprotein-cholesterol response to statin treatment--a pilot study.

7 July 2018

1 reference

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Regulation of lovastatin on a key inflammation-related microRNA in myocardial cells

7 July 2018

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Pharmacogenomics, lipid disorders, and treatment options

7 July 2018

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7 July 2018

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Diagnosis, prevention, and management of statin adverse effects and intolerance: Canadian Working Group Consensus update

7 July 2018

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Association between statin use and colorectal cancer risk: a meta-analysis of 42 studies

7 July 2018

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Evaluation of the pharmacokinetics and drug interactions of the two recently developed statins, rosuvastatin and pitavastatin

7 July 2018

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SLCO1B1 genetic variant associated with statin-induced myopathy: a proof-of-concept study using the clinical practice research datalink

7 July 2018

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7 July 2018

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Comparative tolerability and harms of individual statins: a study-level network meta-analysis of 246 955 participants from 135 randomized, controlled trials

7 July 2018

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7 July 2018

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Statins and the risk of lung cancer: a meta-analysis

7 July 2018

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7 July 2018

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Statin use and risk of bladder cancer: a meta-analysis

7 July 2018

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Statins are associated with reduced risk of esophageal cancer, particularly in patients with Barrett's esophagus: a systematic review and meta-analysis

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Statins and primary liver cancer: a meta-analysis of observational studies.

7 July 2018

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7 July 2018

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Lipid-lowering effect of fluvastatin in relation to cytochrome P450 2C9 variant alleles frequently distributed in the Czech population.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Statin use and risk of pancreatic cancer: a meta-analysis.

7 July 2018

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7 July 2018

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Genetic variation in the ABCC2 gene is associated with dose decreases or switches to other cholesterol-lowering drugs during simvastatin and atorvastatin therapy

7 July 2018

1 reference

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7 July 2018

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7 July 2018

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A systematic review on pharmacogenetics in cardiovascular disease: is it ready for clinical application?

7 July 2018

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Clinical response to statins: mechanism(s) of variable activity and adverse effects

7 July 2018

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Cerivastatin, genetic variants, and the risk of rhabdomyolysis

7 July 2018

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Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic drug uptake

7 July 2018

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Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associated with simvastatin and atorvastatin.

7 July 2018

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Common nonsynonymous substitutions in SLCO1B1 predispose to statin intolerance in routinely treated individuals with type 2 diabetes: a go-DARTS study

7 July 2018

1 reference

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The ABCG2 transporter and its relations with the pharmacokinetics, drug interaction and lipid-lowering effects of statins

7 July 2018

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Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients

7 July 2018

1 reference

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Treatment of dyslipidemia in HIV-infected patients

7 July 2018

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MiR-33 contributes to the regulation of cholesterol homeostasis.

7 July 2018

1 reference

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Efflux and uptake transporters as determinants of statin response.

7 July 2018

1 reference

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Genome-wide association of lipid-lowering response to statins in combined study populations

7 July 2018

1 reference

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Hepatic metabolism and transporter gene variants enhance response to rosuvastatin in patients with acute myocardial infarction: the GEOSTAT-1 Study

7 July 2018

1 reference

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Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part I.

7 July 2018

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Comprehensive whole-genome and candidate gene analysis for response to statin therapy in the Treating to New Targets (TNT) cohort

7 July 2018

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Transporter pharmacogenetics and statin toxicity

7 July 2018

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The SLCO1B1*5 genetic variant is associated with statin-induced side effects

7 July 2018

1 reference

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Impact of OATP transporters on pharmacokinetics

7 July 2018

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Epigenetics: definition, mechanisms and clinical perspective.

7 July 2018

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Statin regulation of CYP3A4 and CYP3A5 expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Narrative review: statin-related myopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Genetic polymorphisms of uptake (OATP1B1, 1B3) and efflux (MRP2, BCRP) transporters: implications for inter-individual differences in the pharmacokinetics and pharmacodynamics of statins and other clinically relevant drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Effect of atorvastatin on microRNA 221 / 222 expression in endothelial progenitor cells obtained from patients with coronary artery disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Pitavastatin attenuates leukocyte-endothelial interactions induced by ischemia-reperfusion injury in the rat retina

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Statin adverse effects : a review of the literature and evidence for a mitochondrial mechanism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Pharmacogenetics of apolipoprotein E gene during lipid-lowering therapy: lipid levels and prevention of coronary heart disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

ABCB1 and ABCC1 expression in peripheral mononuclear cells is influenced by gene polymorphisms and atorvastatin treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

SLCO1B1 variants and statin-induced myopathy--a genomewide study

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Involvement of multiple transporters in the hepatobiliary transport of rosuvastatin

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Association of cholesteryl ester transfer protein genotypes with CETP mass and activity, lipid levels, and coronary risk

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Role of OATP transporters in the disposition of drugs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Pharmacogenomics of statin response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Clinical implications of pharmacogenomics of statin treatment

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Statins and cancer risk: a meta-analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Polymorphisms of OATP-C (SLC21A6) and OAT3 (SLC22A8) genes: consequences for pravastatin pharmacokinetics

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Drug interactions and the statins.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Statins as potent antiinflammatory drugs

7 July 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

CYP2D6*4 polymorphism is associated with statin-induced muscle effects

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Statin therapy correlated CYP2D6 gene polymorphism and hyperlipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

CYP3A4 genotypes and plasma lipoprotein levels before and after treatment with atorvastatin in primary hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

No effect of CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) on lipid-lowering response to statins in Greek patients with primary hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Lipid-lowering response to statins is affected by CYP3A5 polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Identification of genetic variants associated with response to statin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Common genetic variation in the ABCB1 gene is associated with the cholesterol-lowering effect of simvastatin in males

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Impact of ABCC2, ABCG2 and SLCO1B1 polymorphisms on the pharmacokinetics of pitavastatin in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

An association study of 43 SNPs in 16 candidate genes with atorvastatin response

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

APOE gene polymorphisms and response to statin therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

A paucimorphic variant in the HMG-CoA reductase gene is associated with lipid-lowering response to statin treatment in diabetes: a GoDARTS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Pharmacogenetic study of statin therapy and cholesterol reduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Variation in the 3-hydroxyl-3-methylglutaryl coenzyme a reductase gene is associated with racial differences in low-density lipoprotein cholesterol response to simvastatin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Baseline levels of low-density lipoprotein cholesterol and lipoprotein (a) and the AvaII polymorphism of the low-density lipoprotein receptor gene influence the response of low-density lipoprotein cholesterol to pravastatin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Polymorphism in KIF6 gene and benefit from statins after acute coronary syndromes: results from the PROVE IT-TIMI 22 study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

POR*28 SNP is associated with lipid response to atorvastatin in children and adolescents with familial hypercholesterolemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Transporter-mediated influx and efflux mechanisms of pitavastatin, a new inhibitor of HMG-CoA reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Influence of OATP1B1 genotype on the pharmacokinetics of rosuvastatin in Koreans.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Statins control oxidized LDL-mediated histone modifications and gene expression in cultured human endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Expression of miR-146a/b is associated with the Toll-like receptor 4 signal in coronary artery disease: effect of renin-angiotensin system blockade and statins on miRNA-146a/b and Toll-like receptor 4 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Prevention Conference V : Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Noninvasive Tests of Atherosclerotic Burden : Writing Group III

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Inflammatory stress induces statin resistance by disrupting 3-hydroxy-3-methylglutaryl-CoA reductase feedback regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Pharmacokinetic interaction studies of co-administration of ticagrelor and atorvastatin or simvastatin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Metabolism and excretion of rivaroxaban, an oral, direct factor Xa inhibitor, in rats, dogs, and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

CYP2C9 Genetic Polymorphism is a Potential Predictive Marker for the Efficacy of Rosuvastatin Therapy.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Atorvastatin-induced endothelial nitric oxide synthase expression in endothelial cells is mediated by endoglin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

ABCB1 gene polymorphisms, ABCB1 haplotypes and ABCG2 c.421c > A are determinants of inter-subject variability in rosuvastatin pharmacokinetics.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Effect of linagliptin (BI 1356) on the steady-state pharmacokinetics of simvastatin

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Rosuvastatin demonstrates greater reduction of low-density lipoprotein cholesterol compared with pravastatin and simvastatin in hypercholesterolaemic patients: a randomized, double-blind study.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5297738

Tolerability of statins is not linked to CYP450 polymorphisms, but reduced CYP2D6 metabolism improves cholesteraemic response to simvastatin and fluvastatin

26 October 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Association of genetic polymorphism in ABCC2 with hepatic multidrug resistance-associated protein 2 expression and pravastatin pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

SLCO1B1 polymorphism markedly affects the pharmacokinetics of simvastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics of Atorvastatin and Rosuvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS18010104

Impact of variants within seven candidate genes on statin treatment efficacy

21 January 2018

1 reference

12 December 2020

The genetic determinants of the CYP3A5 polymorphism

1 reference

12 December 2020

Rosuvastatin may reduce the incidence of cardiovascular events in patients with acute coronary syndromes receiving percutaneous coronary intervention by suppressing miR-155/SHIP-1 signaling pathway

1 reference

12 December 2020

The C3435T polymorphism in ABCB1 influences atorvastatin efficacy and muscle symptoms in a high-risk vascular cohort

1 reference

12 December 2020

Inflammation and lipid profile in rheumatoid arthritis: bridging an apparent paradox

1 reference

12 December 2020

Altered microRNome Profiling in Statin-Induced HepG2 Cells: A Pilot Study Identifying Potential new Biomarkers Involved in Lipid-Lowering Treatment

1 reference

12 December 2020

CYP2C9 and ABCG2 polymorphisms as risk factors for developing adverse drug reactions in renal transplant patients taking fluvastatin: a case-control study

1 reference

12 December 2020

ABCG2 gene polymorphisms as risk factors for atorvastatin adverse reactions: a case-control study

1 reference

12 December 2020

Effect of apolipoprotein E and A-IV phenotypes on the low density lipoprotein response to HMG CoA reductase inhibitor therapy

1 reference

12 December 2020

The Role of a Common Variant of the Cholesteryl Ester Transfer Protein Gene in the Progression of Coronary Atherosclerosis

1 reference

12 December 2020

The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction : a substudy of the Scandinavian simvastatin survival study

1 reference

12 December 2020

No association between CYP3A4*22 and statin effectiveness in reducing the risk for myocardial infarction

1 reference

12 December 2020

Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability

1 reference

12 December 2020

Absence of clinically relevant interactions between rivaroxaban--an oral, direct Factor Xa inhibitor--and digoxin or atorvastatin in healthy subjects

1 reference

12 December 2020

Genetic determinants of lipid-lowering response to atorvastatin therapy in an Indian population

1 reference

12 December 2020

Interactions between CYP3A5*3 and POR*28 polymorphisms and lipid lowering response with atorvastatin

1 reference

12 December 2020

Simvastatin inhibits leukocyte-endothelial cell interactions and protects against inflammatory processes in normocholesterolemic rats

1 reference

12 December 2020

Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS18010104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28067828%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

28067828

1 reference