Human cytomegalovirus immediate early proteins and cell growth control (Q34683482)

3 August 2017

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title

Human cytomegalovirus immediate early proteins and cell growth control (English)

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3 August 2017

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Jonathan P Castillo

1

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3 August 2017

Timothy F Kowalik

series ordinal

2

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3 August 2017

language of work or name

English

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publication date

1 May 2002

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3 August 2017

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3 August 2017

volume

290

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3 August 2017

issue

1-2

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3 August 2017

page(s)

19-34

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Disruption of PML subnuclear domains by the acidic IE1 protein of human cytomegalovirus is mediated through interaction with PML and may modulate a RING finger-dependent cryptic transactivator function of PML

3 August 2017

cites work

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7 January 2021

The human cytomegalovirus IE2 and UL112-113 proteins accumulate in viral DNA replication compartments that initiate from the periphery of promyelocytic leukemia protein-associated nuclear bodies (PODs or ND10)

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7 January 2021

Evaluation of interactions of human cytomegalovirus immediate-early IE2 regulatory protein with small ubiquitin-like modifiers and their conjugation enzyme Ubc9

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7 January 2021

Malignant transformation of hamster embryo fibroblasts following exposure to ultraviolet-irradiated human cytomegalovirus

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7 January 2021

Human cytomegalovirus tegument protein pp71 (ppUL82) enhances the infectivity of viral DNA and accelerates the infectious cycle

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7 January 2021

Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53

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7 January 2021

Human cytomegalovirus IE2 86-kilodalton protein binds p53 but does not abrogate G1 checkpoint function.

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7 January 2021

Human cytomegalovirus inhibits cellular DNA synthesis and arrests productively infected cells in late G1.

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus 86-kilodalton major immediate-early protein interacts physically and functionally with histone acetyltransferase P/CAF.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Targeting of adenovirus E1A and E4-ORF3 proteins to nuclear matrix-associated PML bodies.

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Role of human cytomegalovirus immediate-early proteins in cell growth control

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus 86K immediate early (IE) 2 protein requires the basic region of the TATA-box binding protein (TBP) for binding, and interacts with TBP and transcription factor TFIIB via regions of IE2 required for transcriptional regulatio

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Identification and mapping of dimerization and DNA-binding domains in the C terminus of the IE2 regulatory protein of human cytomegalovirus

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The retinoblastoma gene product negatively regulates transcriptional activation mediated by the human cytomegalovirus IE2 protein

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus UL37 immediate-early regulatory proteins traffic through the secretory apparatus and to mitochondria

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus and human herpesvirus 6 genes that transform and transactivate

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7 January 2021

Adenovirus replication is coupled with the dynamic properties of the PML nuclear structure.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Oncogenic Transformation of Human Embryo Lung Cells by Human Cytomegalovirus

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7 January 2021

A cytomegalovirus-encoded mitochondria-localized inhibitor of apoptosis structurally unrelated to Bcl-2.

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Activation of p53 by conjugation to the ubiquitin-like protein SUMO-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus 80-kilodalton but not the 72-kilodalton immediate-early protein transactivates heterologous promoters in a TATA box-dependent mechanism and interacts directly with TFIID.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Functional interaction between the HCMV IE2 transactivator and the retinoblastoma protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus UL69 protein is required for efficient accumulation of infected cells in the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Intracellular localization and expression of the human cytomegalovirus matrix phosphoprotein pp71 (ppUL82): evidence for its translocation into the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Covalent modification of the transactivator protein IE2-p86 of human cytomegalovirus by conjugation to the ubiquitin-homologous proteins SUMO-1 and hSMT3b

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

PML is critical for ND10 formation and recruits the PML-interacting protein daxx to this nuclear structure when modified by SUMO-1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Domain mapping of the human cytomegalovirus IE1-72 and cellular p107 protein-protein interaction and the possible functional consequences

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Direct interaction of the human cytomegalovirus IE86 protein with the cis repression signal does not preclude TBP from binding to the TATA box.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus IE86 protein interacts with promoter-bound TATA-binding protein via a specific region distinct from the autorepression domain

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Transactivation activity of the human cytomegalovirus IE2 protein occurs at steps subsequent to TATA box-binding protein recruitment

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus IE1 protein activates AP-1 through a cellular protein kinase(s)

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

In vivo and in vitro analysis of transcriptional activation mediated by the human cytomegalovirus major immediate-early proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis

1 reference

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7 January 2021

Transcriptional activation by the human cytomegalovirus immediate-early proteins: requirements for simple promoter structures and interactions with multiple components of the transcription complex.

1 reference

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7 January 2021

Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins

1 reference

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7 January 2021

Human cytomegalovirus with IE-2 (UL122) deleted fails to express early lytic genes

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7 January 2021

Nuclear domain 10, the site of DNA virus transcription and replication

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7 January 2021

Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0).

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Review: properties and assembly mechanisms of ND10, PML bodies, or PODs

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Regulation of apoptosis in transgenic mice by simian virus 40 T antigen-mediated inactivation of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

c-Jun and p53 Activity Is Modulated by SUMO-1 Modification

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus IE86 protein can block cell cycle progression after inducing transition into the S phase of permissive cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Functional analysis of E2F transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Identification of a viral kinase that phosphorylates specific E2Fs and pocket proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Eleven loci encoding trans-acting factors are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Open reading frames UL44, IRS1/TRS1, and UL36-38 are required for transient complementation of human cytomegalovirus oriLyt-dependent DNA synthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Characterization of phosphoproteins and protein kinase activity of virions, noninfectious enveloped particles, and dense bodies of human cytomegalovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

SUMO-1 modification activates the transcriptional response of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Characterization of the human cytomegalovirus irs1 and trs1 genes: a second immediate-early transcription unit within irs1 whose product antagonizes transcriptional activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

pIRS1 and pTRS1 are present in human cytomegalovirus virions

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Primary structure and transcription of the genes coding for the two virion phosphoproteins pp65 and pp71 of human cytomegalovirus

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Site-specific binding of the human cytomegalovirus IE2 86-kilodalton protein to an early gene promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus IE2 86-kilodalton protein interacts with an early gene promoter via site-specific DNA binding and protein-protein associations

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

High rate of concurrent genital infections with human cytomegalovirus and human papillomaviruses in cervical cancer patients

1 reference

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7 January 2021

Human cytomagalovirus IE1 and IE2 proteins are mutagenic and mediate "hit-and-run" oncogenic transformation in cooperation with the adenovirus E1A proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Effect of the human cytomegalovirus IE86 protein on expression of E2F-responsive genes: a DNA microarray analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Potential role of human cytomegalovirus and p53 interaction in coronary restenosis

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus chemokine receptor US28 mediates vascular smooth muscle cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Effects of human cytomegalovirus immediate-early proteins on p53-mediated apoptosis in coronary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Expression of the human cytomegalovirus UL36–38 immediate early region during permissive infection

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Sibling rivalry in the E2F family

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

A 10-base-pair element of the human immunodeficiency virus type 1 long terminal repeat (LTR) is an absolute requirement for transactivation by the human cytomegalovirus 72-kilodalton IE1 protein but can be compensated for by other LTR regions in tra

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

The human cytomegalovirus immediate early 2 protein dissociates cellular DNA synthesis from cyclin-dependent kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

UL69 of human cytomegalovirus, an open reading frame with homology to ICP27 of herpes simplex virus, encodes a transactivator of gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Functional interaction between pleiotropic transactivator pUL69 of human cytomegalovirus and the human homolog of yeast chromatin regulatory protein SPT6

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Mutations of the human cytomegalovirus immediate-early 2 protein defines regions and amino acid motifs important in transactivation of transcription from the HIV-1 LTR promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters

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https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

Association between prior cytomegalovirus infection and the risk of restenosis after coronary atherectomy

1 reference

https://api.crossref.org/works/10.1016%2FS0378-1119%2802%2900566-8

7 January 2021

10.1016/S0378-1119(02)00566-8

Identifiers

DOI

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3 August 2017

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