Transdifferentiation of pancreatic α-cells into insulin-secreting cells: From experimental models to underlying mechanisms (Q34699211)

4 August 2017

1 reference

title

Transdifferentiation of pancreatic α-cells into insulin-secreting cells: From experimental models to underlying mechanisms (English)

1 reference

4 August 2017

Jieli Lu

1

1 reference

4 August 2017

Rami Jaafer

2

1 reference

4 August 2017

Rémy Bonnavion

3

1 reference

4 August 2017

Philippe Bertolino

4

1 reference

4 August 2017

Chang-Xian Zhang

5

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4 August 2017

publication date

1 December 2014

1 reference

World journal of diabetes

4 August 2017

published in

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4 August 2017

volume

5

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4 August 2017

issue

6

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4 August 2017

page(s)

847-853

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The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells

4 August 2017

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7 July 2018

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7 July 2018

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Epigenomic plasticity enables human pancreatic α to β cell reprogramming.

7 July 2018

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7 July 2018

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Nkx2.2 repressor complex regulates islet β-cell specification and prevents β-to-α-cell reprogramming

7 July 2018

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Pancreatic neuroendocrine tumors in glucagon receptor-deficient mice

7 July 2018

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Context-specific α- to-β-cell reprogramming by forced Pdx1 expression.

7 July 2018

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Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.

7 July 2018

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

7 July 2018

1 reference

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Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.

7 July 2018

1 reference

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Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells

7 July 2018

1 reference

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

7 July 2018

1 reference

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Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor

7 July 2018

1 reference

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

7 July 2018

1 reference

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Glucagon receptor antagonism improves islet function in mice with insulin resistance induced by a high-fat diet

7 July 2018

1 reference

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Ablation of the glucagon receptor gene increases fetal lethality and produces alterations in islet development and maturation

7 July 2018

1 reference

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Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific Gs alpha deficiency

7 July 2018

1 reference

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Regulation of pancreatic beta-cell mass

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the alpha- and beta-cell lineages in the mouse endocrine pancreas

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

A newt's eye view of lens regeneration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Plasticity in the adult rat pancreas: transdifferentiation of exocrine to hepatocyte-like cells in primary culture

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Opposing actions of Arx and Pax4 in endocrine pancreas development

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Recapitulation of embryonic neuroendocrine differentiation in adult human pancreatic duct cells expressing neurogenin 3

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Molecular basis of transdifferentiation of pancreas to liver

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Modulation of rat pancreatic acinoductal transdifferentiation and expression of PDX-1 in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Intermediate endocrine-acinar pancreatic cells in duct ligation conditions.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Betacellulin and activin A coordinately convert amylase-secreting pancreatic AR42J cells into insulin-secreting cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Pancreatic β-cell neogenesis by direct conversion from mature α-cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Regulation of pancreatic beta-cell mass and proliferation by SOCS-3.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

In vitro generation of insulin-producing beta cells from adult exocrine pancreatic cells

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Metabolic adaptations to chronic glucose infusion in rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Exocrine cell transdifferentiation in dexamethasone-treated rat pancreas

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

beta-cell neogenesis during prolonged hyperglycemia in rats

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Gastrin stimulates beta-cell neogenesis and increases islet mass from transdifferentiated but not from normal exocrine pancreas tissue

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

Mitogenic effect of gastrin and expression of gastrin receptors in duct-like cells of rat pancreas

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4265870

The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

26 October 2018

1 reference

12 December 2020

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function

1 reference

12 December 2020

Almost total conversion of pancreas to liver in the adult rat: a reliable model to study transdifferentiation

1 reference

12 December 2020

Glucagon-like peptide 1 and exendin-4 convert pancreatic AR42J cells into glucagon- and insulin-producing cells

1 reference

12 December 2020

Identifiers

DOI

10.4239/WJD.V5.I6.847

1 reference

release_mwwnaa5gmfdtjnptjcn5wzrpqa

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/mwwnaa5gmfdtjnptjcn5wzrpqa

24 November 2022

mapped directly with Wikidata item

PMC publication ID

4265870

1 reference

4 August 2017

1 reference