Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation (Q34699697)

4 August 2017

title

Global dissociation of HuR-mRNA complexes promotes cell survival after ionizing radiation (English)

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12

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Myriam Gorospe

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Kotb Abdelmohsen

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4 August 2017

Subramanya Srikantan

4

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Elin Lehrmann

object named as

Elin Lehrmann

10

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Kumiko Tominaga

6

object named as

Kumiko Tominaga

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3

Mihee M Kim

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Roza Selimyan

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4 August 2017

Jennifer L Martindale

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object named as

Jennifer L Martindale

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11

Yongqing Zhang

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4 August 2017

Kiyoshi Masuda

1

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Eun Kyung Lee

5

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4 August 2017

Xiaoling Yang

9

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Jian-Ying Wang

13

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Hyeon Ho Kim

14

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language of work or name

English

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publication date

11 February 2011

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4 August 2017

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4 August 2017

volume

30

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4 August 2017

issue

6

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4 August 2017

page(s)

1040-1053

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Posttranscriptional regulation of cancer traits by HuR

4 August 2017

cites work

1 reference

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7 July 2018

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MicroRNA expression after ionizing radiation in human endothelial cells

7 July 2018

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Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.

7 July 2018

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NF90 selectively represses the translation of target mRNAs bearing an AU-rich signature motif

7 July 2018

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7 July 2018

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HuR recruits let-7/RISC to repress c-Myc expression

7 July 2018

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7 July 2018

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MicroRNA-mediated gene silencing modulates the UV-induced DNA-damage response

7 July 2018

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p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

7 July 2018

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Murine double minute 2: p53-independent roads lead to genome instability or death

7 July 2018

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Upregulation of SOX9 inhibits the growth of human and mouse melanomas and restores their sensitivity to retinoic acid

7 July 2018

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Modification at HuR(S242) alters HuR localization and proliferative influence

7 July 2018

1 reference

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Phosphorylated HuR shuttles in cycles

7 July 2018

1 reference

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Role of CHK2 in cancer development

7 July 2018

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Nuclear HuR accumulation through phosphorylation by Cdk1

7 July 2018

1 reference

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Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Diverse molecular functions of Hu proteins

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Alterations in RNA-binding activities of IRES-regulatory proteins as a mechanism for physiological variability and pathological dysregulation of IGF-IR translational control in human breast tumor cells

7 July 2018

1 reference

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Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA

7 July 2018

1 reference

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AsSIRTing the DNA damage response

7 July 2018

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Posttranscriptional gene regulation by RNA-binding proteins during oxidative stress: implications for cellular senescence

7 July 2018

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The DNA damage response: ten years after

7 July 2018

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CHK2 kinase: cancer susceptibility and cancer therapy - two sides of the same coin?

7 July 2018

1 reference

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Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Activated checkpoint kinase 2 provides a survival signal for tumor cells

7 July 2018

1 reference

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Rare germ line CHEK2 variants identified in breast cancer families encode proteins that show impaired activation

7 July 2018

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Relief of microRNA-mediated translational repression in human cells subjected to stress

7 July 2018

1 reference

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Sex-determining region Y box 4 is a transforming oncogene in human prostate cancer cells

7 July 2018

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Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR

7 July 2018

1 reference

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DNA damage during reoxygenation elicits a Chk2-dependent checkpoint response

7 July 2018

1 reference

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Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner

7 July 2018

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Functional identification of the pro-apoptotic effector domain in human Sox4

7 July 2018

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AMP-activated protein kinase-regulated phosphorylation and acetylation of importin alpha1: involvement in the nuclear import of RNA-binding protein HuR.

7 July 2018

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7 July 2018

The Chk2 protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Transportins 1 and 2 are redundant nuclear import factors for hnRNP A1 and HuR

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

MK2-induced tristetraprolin:14-3-3 complexes prevent stress granule association and ARE-mRNA decay

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Identification of a target RNA motif for RNA-binding protein HuR.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Transportin2 functions as importin and mediates nuclear import of HuR

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Chk1 and Chk2 kinases in checkpoint control and cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Chk2 activates E2F-1 in response to DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

Chk2-deficient mice exhibit radioresistance and defective p53-mediated transcription

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3061031

The Bcl2 family: regulators of the cellular life-or-death switch

7 July 2018

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Delineation of mRNA export pathways by the use of cell-permeable peptides

7 July 2018

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ASPP proteins specifically stimulate the apoptotic function of p53

7 July 2018

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The many substrates and functions of ATM

7 July 2018

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HuR regulates p21 mRNA stabilization by UV light

7 July 2018

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Why is Hu where? Shuttling of early-response-gene messenger RNA subsets

7 July 2018

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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

7 July 2018

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Submembranous junctional plaque proteins include potential tumor suppressor molecules

7 July 2018

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Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

7 July 2018

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Mutations in SOX9, the gene responsible for Campomelic dysplasia and autosomal sex reversal

7 July 2018

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Uncommon CHEK2 mis-sense variant and reduced risk of tobacco-related cancers: case control study.

7 July 2018

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The Chk2 tumor suppressor is not required for p53 responses in human cancer cells

21 January 2018

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Posttranscriptional derepression of GADD45alpha by genotoxic stress.

21 January 2018

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RAS oncogenes: the first 30 years.

21 January 2018

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Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

21 January 2018

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A kinase from fission yeast responsible for blocking mitosis in S phase

21 January 2018

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UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.

21 January 2018

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HuR-SIRT: the hairy world of posttranscriptional control

26 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/21317874

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2011.24

1 reference

4 August 2017

1 reference

4 August 2017

1 reference