The mechano-gated K(2P) channel TREK-1. (Q34764828)

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English	The mechano-gated K(2P) channel TREK-1.	scientific article

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instance of

scholarly article

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

review article

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Europe PubMed Central

title

The mechano-gated K(2P) channel TREK-1. (English)

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

author name string

Alexandra Dedman

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1

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

Reza Sharif-Naeini

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2

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

Joost H A Folgering

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3

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

Fabrice Duprat

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4

1 reference

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

Amanda Patel

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5

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

Eric Honoré

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6

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stated in

Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

publication date

28 March 2008

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

published in

European Biophysics Journal

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

volume

38

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

issue

3

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Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

page(s)

293-303

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Europe PubMed Central

PubMed publication ID

18369610

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4 August 2017

cites work

Cloning and functional expression of a novel cardiac two-pore background K+ channel (cTBAK-1).

1 reference

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Crossref

reference URL

https://api.crossref.org/works/10.1007%2FS00249-008-0318-8

retrieved

21 January 2018

Mechano- or acid stimulation, two interactive modes of activation of the TREK-1 potassium channel.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PIP2 hydrolysis underlies agonist-induced inhibition and regulates voltage gating of two-pore domain K+ channels.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trichloroethanol enhances the activity of recombinant human TREK-1 and TRAAK channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the Mechano-Gated K2P Channel TREK-1 by Membrane Phospholipids

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyunsaturated fatty acids are cerebral vasodilators via the TREK-1 potassium channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuronal background K2P channels: focus on TREK1

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular basis of the voltage-dependent gating of TREK-1, a mechano-sensitive K(+) channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TASK, a human background K+ channel to sense external pH variations near physiological pH

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREK-1, a K+ channel involved in polymodal pain perception

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TASK-1 is a highly modulated pH-sensitive 'leak' K(+) channel expressed in brainstem respiratory neurons

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophosphatidic acid-operated K+ channels.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kcnkø: single, cloned potassium leak channels are multi-ion pores

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human TREK2, a 2P domain mechano-sensitive K+ channel with multiple regulations by polyunsaturated fatty acids, lysophospholipids, and Gs, Gi, and Gq protein-coupled receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, functional expression and brain localization of a novel unconventional outward rectifier K+ channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beam me up, Scottie! TREK channels swing both ways

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Forward transport. 14-3-3 binding overcomes retention in endoplasmic reticulum by dibasic signals

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Background K+ channels: an important target for volatile anesthetics?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a novel pH-sensitive two pore domain K+ channel from human kidney

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyunsaturated fatty acids are potent neuroprotectors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhalational anesthetics activate two-pore-domain background K+ channels

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biological membranes as bilayer couples. A molecular mechanism of drug-erythrocyte interactions

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An intracellular proton sensor commands lipid- and mechano-gating of the K(+) channel TREK-1.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution analysis of human two pore domain potassium channels in tissues of the central nervous system and periphery

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p11, an annexin II subunit, an auxiliary protein associated with the background K+ channel, TASK-1

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipid and mechano-gated 2P domain K(+) channels.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polyunsaturated fatty acids induce ischemic and epileptic tolerance.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Does sumoylation control K2P1/TWIK1 background K+ channels?

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotype

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential phosphorylation mediates receptor- and kinase-induced inhibition of TREK-1 background potassium channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mammalian two pore domain mechano-gated S-like K+ channel

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Linolenic acid prevents neuronal cell death and paraplegia after transient spinal cord ischemia in rats

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lysophospholipids open the two-pore domain mechano-gated K(+) channels TREK-1 and TRAAK.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREK-1, a K+ channel involved in neuroprotection and general anesthesia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pH-sensitive yeast outward rectifier K+ channel with two pore domains and novel gating properties

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

YKC1 encodes the depolarization‐activated K+ channel in the plasma membrane of yeast

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The S. cerevisiae outwardly-rectifying potassium channel (DUK1) identifies a new family of channels with duplicated pore domains

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Properties and modulation of mammalian 2P domain K+ channels.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cns distribution of members of the two-pore-domain (KCNK) potassium channel family.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The retention factor p11 confers an endoplasmic reticulum-localization signal to the potassium channel TASK-1

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacology of neuronal background potassium channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Desensitization of mechano-gated K2P channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A phospholipid sensor controls mechanogating of the K+ channel TREK-1.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREK-1 regulation by nitric oxide and cGMP-dependent protein kinase. An essential role in smooth muscle inhibitory neurotransmission

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-pore domain K+ channels-molecular sensors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The TREK K2P channels and their role in general anaesthesia and neuroprotection

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-pore-domain K+ channels are a novel target for the anesthetic gases xenon, nitrous oxide, and cyclopropane

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of TASK-1 (Kcnk3) and TASK-3 (Kcnk9) potassium channels: volatile anesthetics and neurotransmitters share a molecular site of action

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potent protective role of lysophospholipids against global cerebral ischemia and glutamate excitotoxicity in neuronal cultures

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered acetylcholine, bradykinin and cutaneous pressure-induced vasodilation in mice lacking the TREK1 potassium channel: the endothelial link

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New structure and function in plant K+ channels: KCO1, an outward rectifier with a steep Ca2+ dependency

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREK-1 is a heat-activated background K(+) channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sumoylation silences the plasma membrane leak K+ channel K2P1.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanosensitive ion channels of E. coli activated by amphipaths.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two-pore-Domain (KCNK) potassium channels: dynamic roles in neuronal function

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TREKing toward new antidepressants

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anesthetic-sensitive 2P domain K+ channels.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TWIK-2, an inactivating 2P domain K+ channel

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the human two-pore domain potassium channel, TREK-1, by fluoxetine and its metabolite norfluoxetine

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fatty acid-sensitive two-pore domain K+ channels

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Extracellular conserved cysteine forms an intersubunit disulphide bridge in the KCNK5 (TASK-2) K+ channel without having an essential effect upon activity

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Eight potassium channel families revealed by the C. elegans genome project

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A neuronal two P domain K+ channel stimulated by arachidonic acid and polyunsaturated fatty acids.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORK1, a potassium-selective leak channel with two pore domains cloned from Drosophila melanogaster by expression in Saccharomyces cerevisiae

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium leak channels and the KCNK family of two-P-domain subunits

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization of TWIK-1 K+ channel subunits via a disulfide bridge

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and functional properties of two-pore-domain potassium channels.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/18369610

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S00249-008-0318-8

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

PubMed publication ID

18369610

1 reference

stated in

Europe PubMed Central

PubMed publication ID

18369610

retrieved

4 August 2017

 

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