Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice (Q34760824)

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English	Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

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Tej Pratap Singh

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Tej Pratap Singh

1

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Michael R Schön

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Michael P Schön

7

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author name string

Barbara Huettner

2

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Europe PubMed Central

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4 August 2017

Harald Koefeler

3

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Europe PubMed Central

PubMed publication ID

4 August 2017

Gerlinde Mayer

4

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

Isabella Bambach

5

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Europe PubMed Central

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4 August 2017

Katrin Wallbrecht

6

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4 August 2017

Peter Wolf

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4 August 2017

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publication date

1 February 2011

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Europe PubMed Central

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4 August 2017

The American Journal of Pathology

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4 August 2017

178

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Europe PubMed Central

PubMed publication ID

4 August 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

699-708

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

8-methoxypsoralen plus ultraviolet A therapy acts via inhibition of the IL-23/Th17 axis and induction of Foxp3+ regulatory T cells involving CTLA4 signaling in a psoriasis-like skin disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Comorbidities in patients with psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Epidermal loss of JunB leads to a SLE phenotype due to hyper IL-6 signaling.

1 reference

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7 July 2018

A role for TGFbeta signaling in the pathogenesis of psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases.

1 reference

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7 July 2018

Th17 cells in rheumatoid arthritis and systemic lupus erythematosus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Inflammatory skin disease in K5.hTGF-beta1 transgenic mice is not dependent on the IL-23/Th17 inflammatory pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

The IL-23/Th17 axis in the immunopathogenesis of psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

IL-23 and IL-12 responses in activated human T cells retrovirally transduced with IL-23 receptor variants

1 reference

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7 July 2018

Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists

1 reference

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7 July 2018

Th17 cells: effector T cells with inflammatory properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor

1 reference

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7 July 2018

Stat3 and Stat4 direct development of IL-17-secreting Th cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

T(H)-17 cells in the circle of immunity and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Pathogenesis and therapy of psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor

1 reference

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7 July 2018

A role for inflammatory mediators in the induction of immunoregulatory B cells

1 reference

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7 July 2018

Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Successful treatment of Von Zumbusch pustular psoriasis with infliximab

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Stat3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Platelet activating factor receptor binding plays a critical role in jet fuel-induced immune suppression

1 reference

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7 July 2018

The effects of an autocrine loop mediated by platelet-activating factor (PAF) in HEC-1A cells are reverted by uteroglobin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Platelet-activating factor, a molecular sensor for cellular damage, activates systemic immune suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Response of psoriasis to interleukin-10 is associated with suppression of cutaneous type 1 inflammation, downregulation of the epidermal interleukin-8/CXCR2 pathway and normalization of keratinocyte maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Evidence for involvement of the epidermal platelet-activating factor receptor in ultraviolet-B-radiation-induced interleukin-8 production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

Activation of the epidermal platelet-activating factor receptor results in cytokine and cyclooxygenase-2 biosynthesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

A cytokine cascade including prostaglandin E2, IL-4, and IL-10 is responsible for UV-induced systemic immune suppression.

1 reference

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7 July 2018

Platelet-activating factor biosynthesis induced by various stimuli in human HaCaT keratinocytes

1 reference

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7 July 2018

Platelet activating factor produced in vitro by Kaposi's sarcoma cells induces and sustains in vivo angiogenesis

1 reference

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7 July 2018

Platelet-activating factor mediates an autocrine proliferative loop in the endometrial adenocarcinoma cell line HEC-1A.

1 reference

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7 July 2018

Identification of functional platelet-activating factor receptors on human keratinocytes

1 reference

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7 July 2018

Role of the microcirculation in the treatment and pathogenesis of psoriasis

1 reference

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7 July 2018

Structural identification of platelet activating factor in psoriatic scale

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

7 July 2018

CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

Complexity of the association between psoriasis and comorbidities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

Psoriasis patients show signs of insulin resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

Reduction of treatment frequency and UVA dose does not substantially compromise the antipsoriatic effect of oral psoralen-UVA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3070583

26 October 2018

Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation

1 reference

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26 October 2018

Activation of Platelet-activating Factor Receptor-coupled Gαq Leads to Stimulation of Src and Focal Adhesion Kinase via Two Separate Pathways in Human Umbilical Vein Endothelial Cells

1 reference

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26 October 2018

High frequency of ultraviolet mutations at the INK4a-ARF locus in squamous cell carcinomas from psoralen-plus-ultraviolet-A-treated psoriasis patients

1 reference

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26 October 2018

Cyclooxygenase-2-issued prostaglandin e(2) enhances the production of endogenous IL-10, which down-regulates dendritic cell functions

1 reference

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26 October 2018

G-protein-independent activation of Tyk2 by the platelet-activating factor receptor

1 reference

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26 October 2018

Phosphorylation of STAT-3 in response to basic fibroblast growth factor occurs through a mechanism involving platelet-activating factor, JAK-2, and Src in human umbilical vein endothelial cells. Evidence for a dual kinase mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21281802

12 December 2020

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Accumulation of inflammatory cells in response to intracutaneous platelet activating factor (Paf-acether) in man

1 reference

https://pubmed.ncbi.nlm.nih.gov/21281802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and quantitation of PAF from psoriatic scales

1 reference

https://pubmed.ncbi.nlm.nih.gov/21281802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intererence of the PAF receptor antagonist, PCA 4248, with the rat pleurisy evoked by inflammatory mediators or allergen

1 reference

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12 December 2020

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Elevated expression of human nonpancreatic phospholipase A2 in psoriatic tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/21281802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of topical application of the platelet-activating factor-antagonist, Ro 24-0238, in psoriasis vulgaris--a clinical and immunohistochemical study

1 reference

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inferred from PubMed ID database lookup

Platelet-activating factor and arachidonic acid metabolites in psoriatic inflammation

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of psoriasis with interleukin-10

1 reference

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Captopril and platelet-activating factor (PAF) antagonist prevent cardiac allograft vasculopathy in rats: role of endogenous PAF and PAF-like compounds

1 reference

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Severe psoriasis pustulosa palmaris et plantaris (Barber-Königsbeck) treated successfully with soluble tumour necrosis factor receptor fusion protein (etanercept)

1 reference

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inferred from PubMed ID database lookup

Two years of experience with etanercept in recalcitrant psoriasis

1 reference

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inferred from PubMed ID database lookup

Long-term control with etanercept (Enbrel) of a severe acrodermatitis continua of Hallopeau refractory to infliximab (Remicade)

1 reference

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Increased activity of interleukin-23/interleukin-17 proinflammatory axis in obese women

1 reference

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Evidence for a cross-talk between human neutrophils and Th17 cells

1 reference

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inferred from PubMed ID database lookup

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10.1016/J.AJPATH.2010.10.008

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

ResearchGate publication ID

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