Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (Q34775526)

4 August 2017

title

Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions (English)

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4 August 2017

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Rocio Sancho

1

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Axel Behrens

object named as

Axel Behrens

6

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author name string

Sophia M Blake

2

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4 August 2017

Christian Tendeng

3

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4 August 2017

Bruce E Clurman

4

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4 August 2017

Julian Lewis

5

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4 August 2017

language of work or name

English

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publication date

11 June 2013

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4 August 2017

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4 August 2017

volume

11

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4 August 2017

issue

6

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4 August 2017

page(s)

e1001586

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Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

11 June 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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7 July 2018

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7 July 2018

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7 July 2018

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Mind bomb 1-expressing intermediate progenitors generate notch signaling to maintain radial glial cells

7 July 2018

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Ubiquitylation of cyclin E requires the sequential function of SCF complexes containing distinct hCdc4 isoforms

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Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

7 July 2018

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Radial glial cells defined and major intermediates between embryonic stem cells and CNS neurons

7 July 2018

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7 July 2018

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7 July 2018

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SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation

7 July 2018

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7 July 2018

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The Notch intracellular domain is ubiquitinated and negatively regulated by the mammalian Sel-10 homolog

7 July 2018

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Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain

7 July 2018

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Radial glial identity is promoted by Notch1 signaling in the murine forebrain

7 July 2018

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Glial cell fate specification modulated by the bHLH gene Hes5 in mouse retina

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Notch1 and Notch2 inhibit myeloid differentiation in response to different cytokines

7 July 2018

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A dominant mutation that predisposes to multiple intestinal neoplasia in the mouse

7 July 2018

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A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size

7 July 2018

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Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun.

21 January 2018

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F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor

21 January 2018

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Notch signalling and the control of cell fate choices in vertebrates.

21 January 2018

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Tissue-specific and inducible Cre-mediated recombination in the gut epithelium

21 January 2018

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The F-box protein Fbw7 is required for cerebellar development

21 January 2018

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Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

21 January 2018

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Hes1 and Hes5 regulate the development of the cranial and spinal nerve systems

21 January 2018

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Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress.

21 January 2018

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Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase

21 January 2018

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CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability

21 January 2018

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Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors

21 January 2018

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Notch signals control the fate of immature progenitor cells in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001586

10.1371/JOURNAL.PBIO.1001586

21 January 2018

Identifiers

DOI

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4 August 2017

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4 August 2017

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