Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis (Q34805086)

4 August 2017

title

Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis (English)

1 reference

4 August 2017

4

1 reference

4 August 2017

Megan L Shaw

5

0 references

Viviana Simon

object named as

Viviana A Simon

series ordinal

3

0 references

Hans-Heinrich Hoffmann

series ordinal

1

object named as

Hans-Heinrich Hoffmann

1 reference

4 August 2017

Andrea Kunz

2

1 reference

4 August 2017

language of work or name

English

0 references

publication date

21 March 2011

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

number of pages

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

4 August 2017

volume

108

1 reference

4 August 2017

issue

14

1 reference

4 August 2017

page(s)

5777-5782

1 reference

Rigid amphipathic fusion inhibitors, small molecule antiviral compounds against enveloped viruses

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Characterization of dengue virus resistance to brequinar in cell culture

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

A broad-spectrum antiviral targeting entry of enveloped viruses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Human host factors required for influenza virus replication

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Cell culture-produced hepatitis C virus does not infect peripheral blood mononuclear cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Modulation of influenza virus replication by alteration of sodium ion transport and protein kinase C activity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Cytidine deamination induced HIV-1 drug resistance

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Identification and characterization of human uracil phosphoribosyltransferase (UPRTase).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Incidence of adamantane resistance among influenza A (H3N2) viruses isolated worldwide from 1994 to 2005: a cause for concern

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Inhibition of human cytomegalovirus signaling and replication by the immunosuppressant FK778.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

In vitro and in vivo activities of anti-influenza virus compound T-705.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Inhibition of herpes simplex virus type 1 by the experimental immunosuppressive agent leflunomide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Leflunomide: an immunomodulatory drug for the treatment of rheumatoid arthritis and other autoimmune diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Novel mechanism of inhibition of cytomegalovirus by the experimental immunosuppressive agent leflunomide.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Therapy of hepatitis C: alpha interferon and ribavirin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Uracil metabolism--UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs.

8 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

8 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.1101143108

Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Mechanism of action of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole), a new broad-spectrum antiviral agent

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Effect of phosphorylated ribavirin on vesicular stomatitis virus transcription

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3078400

Adamantane resistance among influenza A viruses isolated early during the 2005-2006 influenza season in the United States

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1101143108

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1101143108

Multiple inhibitor analysis of the brequinar and leflunomide binding sites on human dihydroorotate dehydrogenase

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1101143108

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21436031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21436031

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1101143108

1 reference

4 August 2017

0 references

1 reference

4 August 2017

1 reference