Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand (Q34805673)

4 August 2017

title

Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand (English)

1 reference

4 August 2017

Bing-Hao Luo

1

1 reference

4 August 2017

Timothy A Springer

series ordinal

2

1 reference

4 August 2017

Junichi Takagi

series ordinal

3

1 reference

4 August 2017

language of work or name

English

0 references

publication date

25 February 2003

1 reference

Proceedings of the National Academy of Sciences of the United States of America

4 August 2017

published in

1 reference

4 August 2017

volume

100

1 reference

4 August 2017

issue

5

1 reference

4 August 2017

page(s)

2403-2408

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

4 August 2017

1 reference

Integrins: bidirectional, allosteric signaling machines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Engineering and design of ligand-induced conformational change in proteins

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Structure of the extracellular region of HER3 reveals an interdomain tether

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Conformational regulation of integrin structure and function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Crystal structure of the extracellular segment of integrin alpha Vbeta3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Allosteric activation of a spring-loaded natriuretic peptide receptor dimer by hormone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Manipulation of ligand binding affinity by exploitation of conformational coupling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Effects of ligand-mimetic peptides Arg-Gly-Asp-X (X = Phe, Trp, Ser) on alphaIIbbeta3 integrin conformation and oligomerization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Long range propagation of conformational changes in integrin alpha IIb beta 3

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Conformation and function of the N-linked glycan in the adhesion domain of human CD2

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Selective inhibition of integrin function by antibodies specific for ligand-occupied receptor conformers.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0438060100

Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0438060100

Ligand binding promotes the entropy-driven oligomerization of integrin alpha IIb beta 3.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0438060100

Glycoproteins of 210,000 and 130,000 m.w. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=151353

Sodium dodecyl sulfate-stable complexes of echistatin and RGD-dependent integrins: a novel approach to study integrins

26 October 2018

1 reference

12 December 2020

Integrin alphaIIb beta3 reconstituted into lipid bilayers is nonclustered in its activated state but clusters after fibrinogen binding

1 reference

12 December 2020

Examination of the platelet membrane glycoprotein IIb-IIIa complex and its interaction with fibrinogen and other ligands by electron microscopy

1 reference

12 December 2020

Classification of 'activation' antibodies against integrin beta1 chain

1 reference

12 December 2020

C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0438060100

1 reference

release_oxcfyr55j5fxfc57pfczlllcni

4 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/oxcfyr55j5fxfc57pfczlllcni

24 November 2022

mapped directly with Wikidata item

PMC publication ID

151353

1 reference

4 August 2017

1 reference