The pathogenesis of pituitary tumours (Q34988259)

5 August 2017

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title

The pathogenesis of pituitary tumours (English)

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5 August 2017

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Sylvia L Asa

1

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Shereen Ezzat

series ordinal

2

object named as

Shereen Ezzat

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5 August 2017

language of work or name

English

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publication date

1 November 2002

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5 August 2017

published in

Nature Reviews Cancer

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5 August 2017

volume

2

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5 August 2017

issue

11

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5 August 2017

page(s)

836-849

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The cytogenesis and pathogenesis of pituitary adenomas

5 August 2017

cites work

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Modern imaging of the pituitary

21 January 2018

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Epidemiology of pituitary adenomas

21 January 2018

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Clonal origin of pituitary adenomas

21 January 2018

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Clinically nonfunctioning pituitary tumors are monoclonal in origin

21 January 2018

1 reference

Two G protein oncogenes in human endocrine tumors

21 January 2018

1 reference

Imprinting of the G(s)alpha gene GNAS1 in the pathogenesis of acromegaly

21 January 2018

1 reference

Clinical characteristics of acromegalic patients whose pituitary tumors contain mutant Gs protein

21 January 2018

1 reference

Clinical, biochemical, and morphological correlates in patients bearing growth hormone-secreting pituitary tumors with or without constitutively active adenylyl cyclase

21 January 2018

1 reference

The cyclic adenosine 3',5'-monophosphate-responsive factor CREB is constitutively activated in human somatotroph adenomas

21 January 2018

1 reference

Pituitary hyperplasia and gigantism in mice caused by a cholera toxin transgene

21 January 2018

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Growth hormone-releasing factor stimulates proliferation of somatotrophs in vitro

21 January 2018

1 reference

Molecular basis of the little mouse phenotype and implications for cell type-specific growth

21 January 2018

1 reference

GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function

21 January 2018

1 reference

Pituitary adenomas in mice transgenic for growth hormone-releasing hormone

21 January 2018

2 references

21 January 2018

Gs alpha and Gi2 alpha mutations in clinically non-functioning pituitary tumours

31 March 2020

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Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex.

21 January 2018

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Protein kinase C activity and expression in normal and adenomatous human pituitaries

21 January 2018

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Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor

21 January 2018

1 reference

Growth hormone-releasing hormone-producing tumors: clinical, biochemical, and morphological manifestations

21 January 2018

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Identification of alternatively spliced messenger ribonucleic acid encoding truncated growth hormone-releasing hormone receptor in human pituitary adenomas

21 January 2018

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Pituitary adenomas of patients with acromegaly express thyrotropin-releasing hormone receptor messenger RNA: cloning and functional expression of the human thyrotropin-releasing hormone receptor gene

21 January 2018

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A novel transcript for the thyrotropin-releasing hormone receptor in human pituitary and pituitary tumors

21 January 2018

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Function of the Homeodomain Protein GHF1 in Pituitary Cell Proliferation

21 January 2018

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Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro

21 January 2018

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Functional role of estrogen in pituitary tumor pathogenesis

21 January 2018

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Targeting of transforming growth factor-alpha expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas.

21 January 2018

1 reference

Corticotropin-releasing hormone and epidermal growth factor: mitogens for anterior pituitary corticotropes

21 January 2018

1 reference

Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice

21 January 2018

1 reference

The c-erbB-2/neu proto-oncogene in human pituitary tumours

21 January 2018

1 reference

Inhibins, activins, and follistatins: gonadal proteins modulating the secretion of follicle-stimulating hormone

21 January 2018

1 reference

Truncated Activin Type I Receptor Alk4 Isoforms Are Dominant Negative Receptors Inhibiting Activin Signaling

21 January 2018

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The Endogenous Fibroblast Growth Factor-2 Antisense Gene Product Regulates Pituitary Cell Growth and Hormone Production

21 January 2018

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Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis

21 January 2018

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Transforming DNA Sequences Present in Human Prolactin-Secreting Pituitary Tumors

21 January 2018

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Pituitary development: regulatory codes in mammalian organogenesis

21 January 2018

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Altered expression of fibroblast growth factor receptors in human pituitary adenomas

21 January 2018

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Targeted expression of a human pituitary tumor-derived isoform of FGF receptor-4 recapitulates pituitary tumorigenesis

21 January 2018

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A soluble dominant negative fibroblast growth factor receptor 4 isoform in human MCF-7 breast cancer cells

21 January 2018

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Isolation and characterization of a pituitary tumor-transforming gene (PTTG)

21 January 2018

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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

21 January 2018

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Cell cycle regulated expression and phosphorylation of hpttg proto-oncogene product

21 January 2018

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Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors

21 January 2018

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Dopamine, the dopamine D2 receptor and pituitary tumours

21 January 2018

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Involvement of p38 mitogen-activated protein kinase activation in bromocriptine-induced apoptosis in rat pituitary GH3 cells

21 January 2018

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Pituitary Lactotroph Hyperplasia and Chronic Hyperprolactinemia in Dopamine D2 Receptor-Deficient Mice

21 January 2018

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Nerve growth factor regulates dopamine D(2) receptor expression in prolactinoma cell lines via p75(NGFR)-mediated activation of nuclear factor-kappaB.

21 January 2018

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Lack of prolactin receptor signaling in mice results in lactotroph proliferation and prolactinomas by dopamine-dependent and -independent mechanisms

21 January 2018

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Autoregulation of the rat prolactin gene in lactotrophs

21 January 2018

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Presence and characterization of the somatostatin precursor in normal human pituitaries and in growth hormone secreting adenomas

21 January 2018

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The growth hormone responses to octreotide in acromegaly correlate with adenoma somatostatin receptor status

21 January 2018

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Somatostatin receptor-specific analogs: effects on cell proliferation and growth hormone secretion in human somatotroph tumors

21 January 2018

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Thyroid hormone-responsive pituitary hyperplasia independent of somatostatin receptor 2.

21 January 2018

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Point mutation causing a single amino acid substitution in the hormone binding domain of the glucocorticoid receptor in familial glucocorticoid resistance

21 January 2018

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Nelson's syndrome associated with a somatic frame shift mutation in the glucocorticoid receptor gene.

21 January 2018

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Aberrant Alternative Splicing of Thyroid Hormone Receptor in a TSH-Secreting Pituitary Tumor Is A Mechanism for Hormone Resistance

21 January 2018

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Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system

21 January 2018

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Gonadotroph cell adenomas of the pituitary

21 January 2018

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Effects of an Rb mutation in the mouse

21 January 2018

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Transfection of an inducible p16/CDKN2A construct mediates reversible growth inhibition and G1 arrest in the AtT20 pituitary tumor cell line

21 January 2018

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

21 January 2018

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Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

21 January 2018

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A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

21 January 2018

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p27 and Rb are on overlapping pathways suppressing tumorigenesis in mice.

21 January 2018

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Reduced expression levels of the cell-cycle inhibitor p27Kip1 in human pituitary adenomas

21 January 2018

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Genetic evidence for the interactions of cyclin D1 and p27(Kip1) in mice

21 January 2018

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CDK inhibitors p18(INK4c) and p27(Kip1) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis

21 January 2018

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p53 gene mutations in pituitary adenomas: rare events

21 January 2018

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Pituitary neoplasia induced by expression of human neurotropic polyomavirus, JCV, early genome in transgenic mice.

21 January 2018

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Localization of the MEN1 gene to a small region within chromosome 11q13 by deletion mapping in tumors

21 January 2018

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Positional cloning of the gene for multiple endocrine neoplasia-type 1

21 January 2018

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Menin represses JunD-activated transcription by a histone deacetylase-dependent mechanism

21 January 2018

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Inactivation of menin, a Smad3-interacting protein, blocks transforming growth factor type beta signaling

21 January 2018

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Adenovirus-mediated retinoblastoma gene therapy suppresses spontaneous pituitary melanotroph tumors in Rb+/- mice

21 January 2018

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Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic application

21 January 2018

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Somatotroph hyperplasia without pituitary adenoma associated with a long standing growth hormone-releasing hormone-producing bronchial carcinoid

21 January 2018

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Epidermal growth factor and its receptor (EGF-R) in human pituitary adenomas: EGF-R correlates with tumor aggressiveness

21 January 2018

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Expression of activin/inhibin subunit messenger ribonucleic acids by gonadotroph adenomas

21 January 2018

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Decreased follistatin gene expression in gonadotroph adenomas

21 January 2018

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Simian Virus 40 T Antigen-Induced Gonadotroph Adenomas: A Model of Human Null Cell Adenomas

21 January 2018

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The MEN-1 Gene Is Rarely Down-Regulated in Pituitary Adenomas

21 January 2018

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Altered Gs and adenylate cyclase activity in human GH-secreting pituitary adenomas

21 January 2018

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Microadenomas of the pituitary and abnormal sellar tomograms in an unselected autopsy series

21 January 2018

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Clonal composition of pituitary adenomas in patients with Cushing's disease: determination by X-chromosome inactivation analysis

31 March 2020

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In vivo responsiveness of morphological variants of growth hormone-producing pituitary adenomas to octreotide

31 March 2020

1 reference

Ras mutations in human pituitary tumors

31 March 2020

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Lack of desensitization of adenomatous somatotrophs to growth-hormone releasing hormone in acromegaly

31 March 2020

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Estradiol induces galanin gene expression in the pituitary of the mouse in an estrogen receptor alpha-dependent manner.

31 March 2020

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Adenovirus-directed expression of dominant negative estrogen receptor induces apoptosis in breast cancer cells and regression of tumors in nude mice.

31 March 2020

1 reference

The role of hormones, growth factors and their receptors in pituitary tumorigenesis.

31 March 2020

1 reference

Targeting of transforming growth factor-alpha expression to pituitary lactotrophs in transgenic mice results in selective lactotroph proliferation and adenomas

31 March 2020

1 reference

The effects of activin on follicle-stimulating hormone secretion and biosynthesis in human glycoprotein hormone-producing pituitary adenomas

31 March 2020

1 reference

Truncated activin type I receptor Alk4 isoforms are dominant negative receptors inhibiting activin signaling

31 March 2020

1 reference

The endogenous fibroblast growth factor-2 antisense gene product regulates pituitary cell growth and hormone production

31 March 2020

1 reference

N-CAM modulates tumour-cell adhesion to matrix by inducing FGF-receptor signalling

31 March 2020

1 reference

Pituitary lactotroph adenomas develop after prolonged lactotroph hyperplasia in dopamine D2 receptor-deficient mice

31 March 2020

1 reference

Thyroid Hormone-Responsive Pituitary Hyperplasia Independent of Somatostatin Receptor 2

31 March 2020

1 reference

Aberrant alternative splicing of thyroid hormone receptor in a TSH-secreting pituitary tumor is a mechanism for hormone resistance

31 March 2020

1 reference

Mutation and expression analysis of the p27/kip1 gene in corticotrophin-secreting tumours

31 March 2020

1 reference

Low expression of the cell cycle inhibitor p27Kip1 in normal corticotroph cells, corticotroph tumors, and malignant pituitary tumors

31 March 2020

1 reference

Vitamin D and its analog EB1089 induce p27 accumulation and diminish association of p27 with Skp2 independent of PTEN in pituitary corticotroph cells.

31 March 2020

1 reference

Simian virus 40 T antigen-induced gonadotroph adenomas: a model of human null cell adenomas

31 March 2020

1 reference

Octreotide treatment of acromegaly. A randomized, multicenter study

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC926

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Dimensions Publication ID

5 August 2017

1024324317

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