Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain (Q34989840)

5 August 2017

title

Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain (English)

1 reference

5 August 2017

Alan Cooper

6

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David Cowburn

object named as

David Cowburn

7

0 references

Asim K Debnath

9

object named as

Asim K Debnath

1 reference

5 August 2017

2

Francesca Curreli

1 reference

5 August 2017

4

Shibani Bhattacharya

1 reference

5 August 2017

8

Eric O Freed

1 reference

5 August 2017

Hongtao Zhang

1

1 reference

5 August 2017

Xihui Zhang

3

1 reference

5 August 2017

Abdul A Waheed

5

1 reference

5 August 2017

publication date

3 May 2011

1 reference

5 August 2017

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5 August 2017

volume

8

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5 August 2017

page(s)

28

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Interplay between HIV entry and transportin-SR2 dependency

5 August 2017

cites work

1 reference

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Atomic-level modelling of the HIV capsid

8 July 2018

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HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention

8 July 2018

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Small-molecule inhibition of human immunodeficiency virus type 1 infection by virus capsid destabilization

8 July 2018

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Flexible use of nuclear import pathways by HIV-1.

8 July 2018

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Structural Convergence between Cryo-EM and NMR Reveals Intersubunit Interactions Critical for HIV-1 Capsid Function

8 July 2018

1 reference

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Direct inhibition of the NOTCH transcription factor complex

8 July 2018

1 reference

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Novel approaches to inhibiting HIV-1 replication.

8 July 2018

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Structure and assembly of immature HIV

8 July 2018

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Virus maturation as a new HIV-1 therapeutic target

8 July 2018

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X-ray structures of the hexameric building block of the HIV capsid

8 July 2018

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Residues in the HIV-1 capsid assembly inhibitor binding site are essential for maintaining the assembly-competent quaternary structure of the capsid protein

8 July 2018

1 reference

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VSV-G pseudotyping rescues HIV-1 CA mutations that impair core assembly or stability.

8 July 2018

1 reference

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Cooperative role of the MHR and the CA dimerization helix in the maturation of the functional retrovirus capsid

8 July 2018

1 reference

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The structural biology of HIV assembly

8 July 2018

1 reference

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Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly.

8 July 2018

1 reference

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A cell-penetrating helical peptide as a potential HIV-1 inhibitor

8 July 2018

1 reference

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Solution structure of a double mutant of the carboxy-terminal dimerization domain of the HIV-1 capsid protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Structure of full-length HIV-1 CA: a model for the mature capsid lattice

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Characterization of the invariable residue 51 mutations of human immunodeficiency virus type 1 capsid protein on in vitro CA assembly and infectivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

HIV-1 capsid protein and cyclophilin a as new targets for anti-AIDS therapeutic agents.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Mutations in capsid major homology region affect assembly and membrane affinity of HIV-1 Gag.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Protein-protein interaction inhibitors: small molecules from screening techniques

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Electron cryotomography of immature HIV-1 virions reveals the structure of the CA and SP1 Gag shells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Mutation in the loop C-terminal to the cyclophilin A binding site of HIV-1 capsid protein disrupts proper virus assembly and infectivity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Domain-swapped dimerization of the HIV-1 capsid C-terminal domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

A stapled BID BH3 helix directly binds and activates BAX

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Mutation of dileucine-like motifs in the human immunodeficiency virus type 1 capsid disrupts virus assembly, gag-gag interactions, gag-membrane binding, and virion maturation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Targeting protein-protein interactions by rational design: mimicry of protein surfaces

8 July 2018

1 reference

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Screening for peptide drugs from the natural repertoire of biodiverse protein folds

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

A domain directly C-terminal to the major homology region of human immunodeficiency type 1 capsid protein plays a crucial role in directing both virus assembly and incorporation of Gag-Pol

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

8 July 2018

1 reference

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The retroviral capsid domain dictates virion size, morphology, and coassembly of gag into virus-like particles

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

A peptide inhibitor of HIV-1 assembly in vitro

8 July 2018

1 reference

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Strategies for targeting protein-protein interactions with synthetic agents.

8 July 2018

1 reference

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Enfuvirtide: the first HIV fusion inhibitor

8 July 2018

1 reference

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HIV-1 assembly and budding as targets for drug discovery.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Virus particle core defects caused by mutations in the human immunodeficiency virus capsid N-terminal domain

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

N-substituted pyrrole derivatives as novel human immunodeficiency virus type 1 entry inhibitors that interfere with the gp41 six-helix bundle formation and block virus fusion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Selected amino acid substitutions in the C-terminal region of human immunodeficiency virus type 1 capsid protein affect virus assembly and release.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

The molecular basis of HIV capsid assembly--five years of progress

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Assembly properties of the human immunodeficiency virus type 1 CA protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Late domain-dependent inhibition of equine infectious anemia virus budding

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Enfuvirtide (T-20): A Novel Human Immunodeficiency Virus Type 1 Fusion Inhibitor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Functional Surfaces of the Human Immunodeficiency Virus Type 1 Capsid Protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Structural organization of authentic, mature HIV-1 virions and cores

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Binding of small molecules to an adaptive protein-protein interface

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Formation of a human immunodeficiency virus type 1 core of optimal stability is crucial for viral replication

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Solution structure and dynamics of Crh, the Bacillus subtilis catabolite repression HPr

8 July 2018

1 reference

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Budding of equine infectious anemia virus is insensitive to proteasome inhibitors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

HIV-1 capsid protein forms spherical (immature-like) and tubular (mature-like) particles in vitro: structure switching by pH-induced conformational changes

8 July 2018

1 reference

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Image reconstructions of helical assemblies of the HIV-1 CA protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

8 July 2018

1 reference

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In vitro assembly properties of purified bacterially expressed capsid proteins of human immunodeficiency virus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

The major homology region of bovine leukaemia virus p24gag is required for virus infectivity in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Engineering human immunodeficiency virus 1 protease heterodimers as macromolecular inhibitors of viral maturation

8 July 2018

1 reference

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Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

8 July 2018

1 reference

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Crystal structure of dimeric HIV-1 capsid protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Evidence for a functional interaction between the V1/V2 and C4 domains of human immunodeficiency virus type 1 envelope glycoprotein gp120.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Virion incorporation of envelope glycoproteins with long but not short cytoplasmic tails is blocked by specific, single amino acid substitutions in the human immunodeficiency virus type 1 matrix.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Generation of high-titer pseudotyped retroviral vectors with very broad host range

8 July 2018

1 reference

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Three-dimensional structures of alpha and beta chemokines.

8 July 2018

1 reference

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Genetic analysis of the major homology region of the Rous sarcoma virus Gag protein

8 July 2018

1 reference

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p6Gag is required for particle production from full-length human immunodeficiency virus type 1 molecular clones expressing protease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Enhancement of human immunodeficiency virus type 1 infection by antisera to peptides from the envelope glycoproteins gp120/gp41

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Mutational analysis of the major homology region of Mason-Pfizer monkey virus by use of saturation mutagenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Assembly and analysis of conical models for the HIV-1 core.

8 July 2018

1 reference

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Electrostatic repulsion, compensatory mutations, and long-range non-additive effects at the dimerization interface of the HIV capsid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Blocking HIV-1 virus assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Interfacial peptide inhibitors of HIV-1 integrase activity and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Interface peptides as structure-based human immunodeficiency virus reverse transcriptase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

The HIV-1 capsid protein C-terminal domain in complex with a virus assembly inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Chemical biology: A Notch above other inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Antiviral inhibition of the HIV-1 capsid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

In vitro identification and characterization of an early complex linking HIV-1 genomic RNA recognition and Pr55Gag multimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Assembly of human immunodeficiency virus precursor gag proteins

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

T-20: first of a new class of anti-HIV drugs

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

T-20: entirely new antiretroviral

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3097154

Peptide and Protein Recognition by Designed Molecules

26 October 2018

1 reference

https://api.crossref.org/works/10.1186%2F1742-4690-8-28

Peptide inhibitors of HIV-1 integrase dissociate the enzyme oligomers

21 January 2018

1 reference

12 December 2020

Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide

1 reference

12 December 2020

Energetics of cyclodextrin-induced dissociation of insulin

1 reference

12 December 2020

Investigation of N-terminal domain charged residues on the assembly and stability of HIV-1 CA

1 reference

12 December 2020

Role of the major homology region in assembly of HIV-1 Gag

1 reference

12 December 2020

Identifiers

DOI

10.1186/1742-4690-8-28

1 reference

Dimensions Publication ID

5 August 2017

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0 references

1 reference

5 August 2017

1 reference