The role of matrix metalloproteinases in vascular disease (Q34981650)

5 August 2017

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title

The role of matrix metalloproteinases in vascular disease (English)

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5 August 2017

I M Loftus

1

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5 August 2017

M M Thompson

series ordinal

2

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5 August 2017

publication date

1 May 2002

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5 August 2017

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5 August 2017

volume

7

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5 August 2017

issue

2

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5 August 2017

page(s)

117-133

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The matrix metalloproteinases and their inhibitors

5 August 2017

cites work

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The family of matrix metalloproteinases

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Matrix metalloproteinase gene expression

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Expression of a metalloproteinase that degrades native type V collagen and denatured collagens by cultured human alveolar macrophages

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A matrix metalloproteinase expressed on the surface of invasive tumour cells

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Matrix metalloproteinases and cardiovascular disease

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The purification of tissue inhibitor of metalloproteinases-2 from its 72 kDa progelatinase complex. Demonstration of the biochemical similarities of tissue inhibitor of metalloproteinases-2 and tissue inhibitor of metalloproteinases-1.

21 January 2018

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Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. Implications for atherosclerotic plaque stability

21 January 2018

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Hypercholesterolemia increases endothelial superoxide anion production

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30 Tissue inhibitors of matrix metalloendopeptidases

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That impish TIMP: the tissue inhibitor of metalloproteinases-3

21 January 2018

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Divergent effects of tissue inhibitor of metalloproteinase-1, -2, or -3 overexpression on rat vascular smooth muscle cell invasion, proliferation, and death in vitro. TIMP-3 promotes apoptosis

21 January 2018

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Elastin content, cross-links, and mRNA in normal and aneurysmal human aorta

21 January 2018

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Elastin degradation in abdominal aortic aneurysms

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The defect in Marfan syndrome

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Cyclic Stretching Stimulates Synthesis of Matrix Components by Arterial Smooth Muscle Cells in Vitro

21 January 2018

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Pathogenesis of abdominal aortic aneurysms--cellular and biochemical mechanisms

21 January 2018

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Characterization of an elastase from aneurysmal aorta which degrades intact aortic elastin

21 January 2018

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Identification of matrix metalloproteinases 3 (stromelysin-1) and 9 (gelatinase B) in abdominal aortic aneurysm

21 January 2018

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Production and localization of 92-kilodalton gelatinase in abdominal aortic aneurysms. An elastolytic metalloproteinase expressed by aneurysm-infiltrating macrophages

21 January 2018

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Urokinase-generated plasmin activates matrix metalloproteinases during aneurysm formation

21 January 2018

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Role of matrix metalloproteinases in abdominal aortic aneurysms

21 January 2018

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Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms

21 January 2018

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Targeted gene disruption of matrix metalloproteinase-9 (gelatinase B) suppresses development of experimental abdominal aortic aneurysms

21 January 2018

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Mechanisms of activation of tissue procollagenase by matrix metalloproteinase 3 (stromelysin)

21 January 2018

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Local overexpression of TIMP-1 prevents aortic aneurysm degeneration and rupture in a rat model

21 January 2018

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Identification of a serum gelatinase associated with the occurrence of cerebral aneurysms as pro-matrix metalloproteinase-2.

21 January 2018

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Pathogenesis of abdominal aortic aneurysm

21 January 2018

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Sibling risks of abdominal aortic aneurysm

21 January 2018

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A review of the histologic changes in vein-to-artery grafts, with particular reference to intimal hyperplasia

21 January 2018

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Primary peripheral arterial stenoses and restenoses excised by transluminal atherectomy: a histopathologic study

21 January 2018

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Induction of collagenase and stromelysin gene expression by mechanical injury in a vascular smooth muscle-derived cell line

21 January 2018

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eNOS gene transfer inhibits smooth muscle cell migration and MMP-2 and MMP-9 activity

21 January 2018

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Immunolocalization of matrix metalloproteinases in rabbit carotid arteries after balloon denudation

21 January 2018

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Reduced transplant arteriosclerosis in plasminogen-deficient mice

21 January 2018

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Expression of tissue inhibitor of matrix metalloproteinases 1 by use of an adenoviral vector inhibits smooth muscle cell migration and reduces neointimal hyperplasia in the rat model of vascular balloon injury

21 January 2018

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Adenovirus-mediated gene transfer of the human TIMP-1 gene inhibits smooth muscle cell migration and neointimal formation in human saphenous vein

21 January 2018

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The pathogenesis of atherosclerosis: a perspective for the 1990s

21 January 2018

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Involvement of extracellular-matrix-degrading metalloproteinases in rabbit aortic smooth-muscle cell proliferation

21 January 2018

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Coronary Plaque Disruption

21 January 2018

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Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary syndromes

21 January 2018

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Elevated white blood cell count and carotid plaque thickness : the northern manhattan stroke study.

21 January 2018

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C-reactive protein in ischemic stroke: an independent prognostic factor.

21 January 2018

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C-reactive protein-mediated low density lipoprotein uptake by macrophages: implications for atherosclerosis

21 January 2018

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Regulation of matrix metalloproteinase activity in ischemic tissue by interleukin-10: role in ischemia-induced angiogenesis

21 January 2018

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Serum levels of the antiinflammatory cytokine interleukin-10 are decreased in patients with unstable angina

21 January 2018

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Localization of stromelysin gene expression in atherosclerotic plaques by in situ hybridization

21 January 2018

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Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

21 January 2018

1 reference

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ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Increased matrix metalloproteinase-9 activity in unstable carotid plaques. A potential role in acute plaque disruption.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Membrane type 1 matrix metalloproteinase expression in human atherosclerotic plaques: evidence for activation by proinflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Matrilysin is expressed by lipid-laden macrophages at sites of potential rupture in atherosclerotic lesions and localizes to areas of versican deposition, a proteoglycan substrate for the enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Lipid lowering by diet reduces matrix metalloproteinase activity and increases collagen content of rabbit atheroma: a potential mechanism of lesion stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Novel clinical markers of vascular wall inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Peripheral blood levels of matrix metalloproteases-2 and -9 are elevated in patients with acute coronary syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Preliminary report: genetic variation in the human stromelysin promoter is associated with progression of coronary atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Stromelysin promoter 5A/6A polymorphism is associated with acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Functional Polymorphism in the Regulatory Region of Gelatinase B Gene in Relation to Severity of Coronary Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Inhibition of collagenolytic activity and metastasis of tumor cells by a recombinant human tissue inhibitor of metalloproteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Therapeutic effect of the matrix metalloproteinase inhibitor, batimastat, in a human colorectal cancer ascites model

21 January 2018

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Matrix metalloproteinase inhibitors: present achievements and future prospects

21 January 2018

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Experimental and clinical studies on the use of matrix metalloproteinase inhibitors for the treatment of cancer

21 January 2018

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Oral matrix metalloproteinase inhibition and arterial remodeling after balloon dilation: an intravascular ultrasound study in the pig.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Suppression of experimental abdominal aortic aneurysms by systemic treatment with a hydroxamate-based matrix metalloproteinase inhibitor (RS 132908).

21 January 2018

1 reference

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Dose-dependent limitation of arterial enlargement by the matrix metalloproteinase inhibitor RS-113,456.

21 January 2018

1 reference

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Blocking periodontal disease progression by inhibiting tissue-destructive enzymes: a potential therapeutic role for tetracyclines and their chemically-modified analogs.

21 January 2018

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Reduction of the severity of canine osteoarthritis by prophylactic treatment with oral doxycycline

21 January 2018

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Uptake of tetracycline by aortic aneurysm wall and its effect on inflammation and proteolysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Prevention of aneurysm development and rupture by local overexpression of plasminogen activator inhibitor-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

The influence of indomethacin on the metabolism and cytokine secretion of human aneurysmal aorta

21 January 2018

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Indomethacin inhibits expansion of experimental aortic aneurysms via inhibition of the cox2 isoform of cyclooxygenase

21 January 2018

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Inhibition of prostaglandin E2 synthesis in abdominal aortic aneurysms: implications for smooth muscle cell viability, inflammatory processes, and the expansion of abdominal aortic aneurysms

21 January 2018

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Natural statins and stroke risk.

21 January 2018

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Reduction of stroke incidence after myocardial infarction with pravastatin: the Cholesterol and Recurrent Events (CARE) study. The Care Investigators

21 January 2018

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Reduction of stroke events with pravastatin: the Prospective Pravastatin Pooling (PPP) Project

21 January 2018

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https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Does pretreatment with statins improve clinical outcome after stroke? A pilot case-referent study

21 January 2018

1 reference

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Effects of lipid-lowering by simvastatin on human atherosclerotic lesions: a longitudinal study by high-resolution, noninvasive magnetic resonance imaging

21 January 2018

1 reference

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Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions

21 January 2018

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Simvastatin exerts both anti-inflammatory and cardioprotective effects in apolipoprotein E-deficient mice.

21 January 2018

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An HMG-CoA reductase inhibitor, cerivastatin, suppresses growth of macrophages expressing matrix metalloproteinases and tissue factor in vivo and in vitro

21 January 2018

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Statins alter smooth muscle cell accumulation and collagen content in established atheroma of watanabe heritable hyperlipidemic rabbits

21 January 2018

1 reference

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Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Rapid reduction in C-reactive protein with cerivastatin among 785 patients with primary hypercholesterolemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Analysis of coding sequences for tissue inhibitor of metalloproteinases 1 (TIMP1) and 2 (TIMP2) in patients with aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Upregulation of Basement Membrane–Degrading Metalloproteinase Secretion After Balloon Injury of Pig Carotid Arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Ubiquitous Elevation of Matrix Metalloproteinase-2 Expression in the Vasculature of Patients With Abdominal Aneurysms

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Marimastat inhibits elastin degradation and matrix metalloproteinase 2 activity in a model of aneurysm disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

Stromelysin-1 and Interleukin-6 Gene Promoter Polymorphisms Are Determinants of Asymptomatic Carotid Artery Atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1191%2F1358863X02VM420RA

10.1191/1358863X02VM420RA

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

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