Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents. (Q35008272)

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31 January 2020

title

Functional relevance of the histone gammaH2Ax in the response to DNA damaging agents (English)

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7

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author name string

Ingrid Revet

1

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31 January 2020

Luzviminda Feeney

2

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31 January 2020

Stephanie Bruguera

3

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31 January 2020

Wade Wilson

4

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31 January 2020

Tiffany K Dong

5

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31 January 2020

Dennis H Oh

6

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31 January 2020

James E Cleaver

8

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31 January 2020

language of work or name

English

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publication date

9 May 2011

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Proceedings of the National Academy of Sciences of the United States of America

31 January 2020

published in

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volume

108

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issue

21

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31 January 2020

page(s)

8663-8667

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describes a project that uses

31 January 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3102364/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

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A minority of foci or pan-nuclear apoptotic staining of gammaH2AX in the S phase after UV damage contain DNA double-strand breaks

8 July 2018

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Kinetics of the UV-induced DNA damage response in relation to cell cycle phase. Correlation with DNA replication

8 July 2018

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Structure and function of histone H2AX.

8 July 2018

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DNA polymerase beta and PARP activities in base excision repair in living cells

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H2AX phosphorylation as a genotoxicity endpoint.

8 July 2018

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Numerical analysis of etoposide induced DNA breaks

8 July 2018

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ATR-Chk1 pathway inhibition promotes apoptosis after UV treatment in primary human keratinocytes: potential basis for the UV protective effects of caffeine

8 July 2018

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Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions

8 July 2018

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DNA double-strand break formation upon UV-induced replication stress activates ATM and DNA-PKcs kinases

8 July 2018

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Mre11-Rad50-Nbs1-dependent processing of DNA breaks generates oligonucleotides that stimulate ATM activity

8 July 2018

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H2AX phosphorylation after UV irradiation is triggered by DNA repair intermediates and is mediated by the ATR kinase.

8 July 2018

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

8 July 2018

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Perturbed gap-filling synthesis in nucleotide excision repair causes histone H2AX phosphorylation in human quiescent cells

8 July 2018

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ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

8 July 2018

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Diverse roles for histone H2A modifications in DNA damage response pathways in yeast

8 July 2018

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Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

8 July 2018

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H2AX phosphorylation within the G1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks

8 July 2018

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DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

8 July 2018

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8 July 2018

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DNA repair: the importance of phosphorylating histone H2AX.

8 July 2018

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Histone H2AX phosphorylation after cell irradiation with UV-B: relationship to cell cycle phase and induction of apoptosis.

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Polymerase eta and p53 jointly regulate cell survival, apoptosis and Mre11 recombination during S phase checkpoint arrest after UV irradiation

8 July 2018

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8 July 2018

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UV-induced replication arrest in the xeroderma pigmentosum variant leads to DNA double-strand breaks, gamma -H2AX formation, and Mre11 relocalization

8 July 2018

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Polymerase eta deficiency in the xeroderma pigmentosum variant uncovers an overlap between the S phase checkpoint and double-strand break repair

8 July 2018

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8 July 2018

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GammaH2AX, an accurate marker that analyzes UV genotoxic effects on human keratinocytes and on human skin.

8 July 2018

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Crossref

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Alternative recombination pathways in UV-irradiated XP variant cells

21 January 2018

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Crossref

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Assessment of DNA double-strand breaks and gammaH2AX induced by the topoisomerase II poisons etoposide and mitoxantrone

21 January 2018

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Crossref

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Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.

21 January 2018

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Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine.

26 October 2018

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26 October 2018

Identifiers

DOI

10.1073/PNAS.1105866108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21555580%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

0 references

1 reference

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PubMed publication ID

21555580

1 reference