Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp (Q35073779)

6 August 2017

title

Antitumor bisdioxopiperazines inhibit yeast DNA topoisomerase II by trapping the enzyme in the form of a closed protein clamp (English)

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6 August 2017

J Roca

1

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6 August 2017

R Ishida

2

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6 August 2017

J M Berger

3

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6 August 2017

T Andoh

4

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6 August 2017

J C Wang

5

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6 August 2017

language of work or name

English

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publication date

1 March 1994

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6 August 2017

number of pages

5

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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6 August 2017

volume

91

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6 August 2017

issue

5

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6 August 2017

page(s)

1781-1785

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On the coupling between ATP usage and DNA transport by yeast DNA topoisomerase II.

6 August 2017

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=43247

Mechanistic aspects of DNA topoisomerases.

8 July 2018

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Inhibitors of DNA topoisomerases

8 July 2018

1 reference

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Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells

8 July 2018

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DNA topoisomerase poisons as antitumor drugs

8 July 2018

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Patterns of strongly protein-associated simian virus 40 DNA replication intermediates resulting from exposures to specific topoisomerase poisons

8 July 2018

1 reference

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Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers

8 July 2018

1 reference

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Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4'-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage.

8 July 2018

1 reference

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DNA topoisomerases: why so many?

8 July 2018

1 reference

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Proteolysis patterns of epitopically labeled yeast DNA topoisomerase II suggest an allosteric transition in the enzyme induced by ATP binding

8 July 2018

1 reference

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Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth

8 July 2018

1 reference

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Topoisomerase II inhibition prevents anaphase chromatid segregation in mammalian cells independently of the generation of DNA strand breaks.

8 July 2018

1 reference

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Function of the hydrophilic carboxyl terminus of type II DNA topoisomerase from Drosophila melanogaster. I. In vitro studies.

27 September 2018

1 reference

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Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors

27 September 2018

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12 December 2020

Study of allosteric communication between protomers by immunotagging

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12 December 2020

Effects of the L isomer (+)-1,2-bis(3,5-dioxopiperazine-1-yl)propane on cell survival and cell cycle progression of cultured mammalian cells

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12 December 2020

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12 December 2020

Inhibition of type II topoisomerase by fostriecin

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12 December 2020

Inducible overexpression, purification, and active site mapping of DNA topoisomerase II from the yeast Saccharomyces cerevisiae

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12 December 2020

Topological complexes between DNA and topoisomerase II and effects of polyamines

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12 December 2020

In vitro and intracellular inhibition of topoisomerase II by the antitumor agent merbarone

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12 December 2020

Mode of Action of the Cytostatic Agent ‘ICRF 159’

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12 December 2020

Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons

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12 December 2020

Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives

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12 December 2020

The capture of a DNA double helix by an ATP-dependent protein clamp: a key step in DNA transport by type II DNA topoisomerases

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.91.5.1781

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6 August 2017

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6 August 2017

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