Liver X Receptor Signaling Pathways in Cardiovascular Disease (Q35104848)

6 August 2017

1 reference

title

Liver X receptor signaling pathways in cardiovascular disease (English)

1 reference

https://api.crossref.org/works/10.1210/ME.2003-0061

6 August 2017

Liver X Receptor Signaling Pathways in Cardiovascular Disease (English)

1 reference

https://api.crossref.org/works/10.1210/ME.2003-0061

23 December 2023

main subject

cardiovascular disease

1 reference

1 reference

23 December 2023

1

Peter Tontonoz

1 reference

6 August 2017

2

David J. Mangelsdorf

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12690094

reference URL

23 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12690094

reference URL

23 December 2023

publication date

10 April 2003

1 reference

full work available at URL

6 August 2017

published in

Molecular Endocrinology

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6 August 2017

volume

17

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6 August 2017

issue

6

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6 August 2017

page(s)

985-993

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Atherosclerosis. the road ahead

6 August 2017

cites work

https://api.crossref.org/works/10.1210/ME.2003-0061

1

1 reference

23 December 2023

Atherosclerosis

https://api.crossref.org/works/10.1210/ME.2003-0061

2

1 reference

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

4

1 reference

An oxysterol signalling pathway mediated by the nuclear receptor LXR alpha

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

5

1 reference

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

6

1 reference

The role of orphan nuclear receptors in the regulation of cholesterol homeostasis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

7

1 reference

LXR, a nuclear receptor that defines a distinct retinoid response pathway

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

8

1 reference

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

9

1 reference

Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

10

1 reference

Control of cholesterol turnover in the mouse

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

11

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Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

12

1 reference

Regulation of absorption and ABC1-mediated efflux of cholesterol by RXR heterodimers

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

13

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Role of LXRs in control of lipogenesis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

14

1 reference

The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

15

1 reference

Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

16

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Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

17

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Increased atherosclerosis in hyperlipidemic mice with inactivation of ABCA1 in macrophages

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

18

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Monocyte/macrophage expression of ABCA1 has minimal contribution to plasma HDL levels

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

19

1 reference

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

20

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The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

21

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Increased ABCA1 activity protects against atherosclerosis.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

22

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Sterol-dependent transactivation of the ABC1 promoter by the liver X receptor/retinoid X receptor

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

23

1 reference

ABC1 gene expression and ApoA-I-mediated cholesterol efflux are regulated by LXR.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

24

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Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

25

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Accumulation of foam cells in liver X receptor-deficient mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

26

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Identification of macrophage liver X receptors as inhibitors of atherosclerosis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

27

1 reference

Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

28

1 reference

ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

29

1 reference

Genetic basis of sitosterolemia

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

30

1 reference

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

31

1 reference

Coexpression of ATP-binding cassette proteins ABCG5 and ABCG8 permits their transport to the apical surface

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

32

1 reference

Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

33

1 reference

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

34

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Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

35

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Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

36

1 reference

Apolipoprotein E and atherosclerosis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

37

1 reference

Duplicated downstream enhancers control expression of the human apolipoprotein E gene in macrophages and adipose tissue

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

38

1 reference

LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

39

1 reference

Macrophage-specific expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

40

1 reference

Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

41

1 reference

Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

42

1 reference

Regulated expression of the apolipoprotein E/C-I/C-IV/C-II gene cluster in murine and human macrophages. A critical role for nuclear liver X receptors alpha and beta

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

43

1 reference

Phospholipid transfer protein is regulated by liver X receptors in vivo

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

44

1 reference

The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

45

1 reference

Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

46

1 reference

Identification of PLTP as an LXR target gene and apoE as an FXR target gene reveals overlapping targets for the two nuclear receptors

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

47

1 reference

Regulation of lipoprotein lipase by the oxysterol receptors, LXRalpha and LXRbeta.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

49

1 reference

Suppression of diet-induced atherosclerosis in low density lipoprotein receptor knockout mice overexpressing lipoprotein lipase

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

50

1 reference

Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in low density lipoprotein receptor-deficient mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

52

1 reference

Macrophage-specific expression of human lipoprotein lipase accelerates atherosclerosis in transgenic apolipoprotein e knockout mice but not in C57BL/6 mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

53

1 reference

23 December 2023

CETP and atherosclerosis

https://api.crossref.org/works/10.1210/ME.2003-0061

54

1 reference

Cholesteryl ester transfer protein activity enhances plasma cholesteryl ester formation. Studies in CETP transgenic mice and human genetic CETP deficiency

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

55

1 reference

Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

56

1 reference

Phospholipid transfer protein

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

57

1 reference

Plasma phospholipid transfer protein. Adenovirus-mediated overexpression in mice leads to decreased plasma high density lipoprotein (HDL) and enhanced hepatic uptake of phospholipids and cholesteryl esters from HDL

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

58

1 reference

Dynamic changes in mouse lipoproteins induced by transiently expressed human phospholipid transfer protein (PLTP): importance of PLTP in prebeta-HDL generation

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

59

1 reference

Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

60

1 reference

Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

61

1 reference

Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

62

1 reference

Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

63

1 reference

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

64

1 reference

Reduction of atherosclerosis in apolipoprotein E knockout mice by activation of the retinoid X receptor.

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

65

1 reference

Inflammation and immune response in atherosclerosis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

66

1 reference

Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

67

1 reference

Atherosclerotic arterial remodeling and the localization of macrophages and matrix metalloproteases 1, 2 and 9 in the human coronary artery

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

68

1 reference

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

69

1 reference

Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

70

1 reference

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

71

1 reference

Autoregulation of the human liver X receptor alpha promoter

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

72

1 reference

PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway

23 December 2023

https://api.crossref.org/works/10.1210/ME.2003-0061

73

1 reference

23 December 2023

Identifiers

DOI

10.1210/ME.2003-0061

1 reference

release_rxj2o7ww7vadlorz7dcoc2gdqi

6 August 2017

Fatcat ID

1 reference

https://api.fatcat.wiki/v0/release/rxj2o7ww7vadlorz7dcoc2gdqi

Fatcat

reference URL

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference