Fine-tuning Notch1 activation by endocytosis and glycosylation (Q35101893)

6 August 2017

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title

Fine-tuning Notch1 activation by endocytosis and glycosylation (English)

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6 August 2017

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Ute Koch

1

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6 August 2017

Julie S Yuan

series ordinal

2

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6 August 2017

James A Harper

series ordinal

3

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6 August 2017

Cynthia J Guidos

series ordinal

4

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6 August 2017

language of work or name

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1 April 2003

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6 August 2017

published in

Seminars in Immunology

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6 August 2017

volume

15

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6 August 2017

issue

2

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6 August 2017

page(s)

99-106

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Notch signaling in vertebrate development and disease

6 August 2017

cites work

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

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7 January 2021

rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells

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Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

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7 January 2021

Radial glial identity is promoted by Notch1 signaling in the murine forebrain

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7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

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7 January 2021

Cutting edge: an essential role for Notch-1 in the development of both thymus-independent and -dependent T cells in the gut.

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7 January 2021

Notch1 expression in early lymphopoiesis influences B versus T lineage determination

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7 January 2021

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

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7 January 2021

Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1.

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7 January 2021

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

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7 January 2021

Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells

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7 January 2021

Notch signaling in lymphocyte development

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7 January 2021

Defects in limb, craniofacial, and thymic development in Jagged2 mutant mice

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7 January 2021

Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation

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7 January 2021

Maintenance of somite borders in mice requires the Delta homologue DII1.

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7 January 2021

The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries

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7 January 2021

Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1

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7 January 2021

Notch signaling: cell fate control and signal integration in development

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7 January 2021

LIN-12/Notch signaling: lessons from worms and flies

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7 January 2021

An EGFR/Ebi/Sno pathway promotes delta expression by inactivating Su(H)/SMRTER repression during inductive notch signaling.

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7 January 2021

Intracellular cell-autonomous association of Notch and its ligands: a novel mechanism of Notch signal modification

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7 January 2021

Requirement for dynamin during Notch signaling in Drosophila neurogenesis.

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7 January 2021

Asymmetric cell division

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7 January 2021

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

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7 January 2021

Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

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7 January 2021

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

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7 January 2021

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

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7 January 2021

The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interaction in sensory organ lineage

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7 January 2021

Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module

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7 January 2021

Numb is an endocytic protein

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7 January 2021

The endocytic protein alpha-Adaptin is required for numb-mediated asymmetric cell division in Drosophila

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7 January 2021

The Mdm2 oncoprotein interacts with the cell fate regulator Numb

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7 January 2021

LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation

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7 January 2021

Protein degradation: four E3s for the notch pathway

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7 January 2021

Mouse numb is an essential gene involved in cortical neurogenesis

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7 January 2021

Multiple roles of mouse Numb in tuning developmental cell fates.

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7 January 2021

Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification

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7 January 2021

Inactivation of Notch1 impairs VDJbeta rearrangement and allows pre-TCR-independent survival of early alpha beta Lineage Thymocytes.

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7 January 2021

Neuralized: regulating notch by putting away delta.

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7 January 2021

neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

1 reference

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7 January 2021

neuralized functions cell-autonomously to regulate a subset of notch-dependent processes during adult Drosophila development.

1 reference

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7 January 2021

Neuralized functions cell autonomously to regulate Drosophila sense organ development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Xenopus neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Neuralized functions as an E3 ubiquitin ligase during Drosophila development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Variations on the Notch pathway in neural development

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Endocytosis and signaling. an inseparable partnership

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Fringe, Notch, and making developmental boundaries.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

fringe, a Boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Fringe modulates Notch-ligand interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Fringe boundaries coincide with Notch-dependent patterning centres in mammals and alter Notch-dependent development in Drosophila

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Expression of notch receptors, notch ligands, and fringe genes in hematopoiesis.

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

lunatic fringe is an essential mediator of somite segmentation and patterning

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Defects in somite formation in lunatic fringe-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Segmentation defects of Notch pathway mutants and absence of a synergistic phenotype in lunatic fringe/radical fringe double mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Fringe differentially modulates Jagged1 and Delta1 signalling through Notch1 and Notch2.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Glycosyltransferase activity of Fringe modulates Notch-Delta interactions.

1 reference

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7 January 2021

Fringe is a glycosyltransferase that modifies Notch

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

The notch signalling regulator fringe acts in the Golgi apparatus and requires the glycosyltransferase signature motif DXD.

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Mammalian Notch1 is modified with two unusual forms of O-linked glycosylation found on epidermal growth factor-like modules

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

T cell progenitors emerge earlier than B cell progenitors in the murine fetal liver

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900006-X

7 January 2021

Clonable progenitors committed to the T lymphocyte lineage in the mouse bone marrow; use of an extrathymic pathway

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7 January 2021

10.1016/S1044-5323(03)00006-X

Identifiers

DOI

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6 August 2017

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