Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90 (Q35102525)

6 August 2017

title

Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90 (English)

1 reference

6 August 2017

1 reference

Carl Gregory

6

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ORCID Public Data File 2021

author name string

Ruth C Matthews

1

1 reference

6 August 2017

Gordon Rigg

2

1 reference

6 August 2017

Samantha Hodgetts

3

1 reference

6 August 2017

Tracey Carter

4

1 reference

6 August 2017

Caroline Chapman

5

1 reference

6 August 2017

Chris Illidge

7

1 reference

6 August 2017

James Burnie

8

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 July 2003

1 reference

Antimicrobial Agents and Chemotherapy

6 August 2017

published in

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6 August 2017

volume

47

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6 August 2017

issue

7

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6 August 2017

page(s)

2208-2216

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In vitro interaction of flucytosine combined with amphotericin B or fluconazole against thirty-five yeast isolates determined by both the fractional inhibitory concentration index and the response surface approach.

6 August 2017

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Plasma protein binding of amphotericin B and pharmacokinetics of bound versus unbound amphotericin B after administration of intravenous liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate

9 July 2018

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Heat shock protein 90 catalyzes activation of the prekallikrein-kininogen complex in the absence of factor XII.

9 July 2018

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A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket

9 July 2018

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Impact of the order of initiation of fluconazole and amphotericin B in sequential or combination therapy on killing of Candida albicans in vitro and in a rabbit model of endocarditis and pyelonephritis

9 July 2018

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9 July 2018

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Cell surface proteins of Candida albicans: preparation of extracts and improved detection of proteins

9 July 2018

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Characterization of heat-inducible expression and cloning of HtpG (Hsp90 homologue) of Porphyromonas gingivalis

9 July 2018

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Immunization with the Candida albicans membrane fraction and in combination with fluconazole protects against systemic fungal infections

9 July 2018

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GHKL, an emergent ATPase/kinase superfamily

9 July 2018

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Purification and identification of secreted oxidative stress-induced factors from vascular smooth muscle cells

9 July 2018

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Interaction between fluconazole and amphotericin B in mice with systemic infection due to fluconazole-susceptible or -resistant strains of Candida albicans

9 July 2018

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Dynamic activation of endothelial nitric oxide synthase by Hsp90.

9 July 2018

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Clinical pharmacology of systemic antifungal agents: a comprehensive review of agents in clinical use, current investigational compounds, and putative targets for antifungal drug development

9 July 2018

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Do in vitro susceptibility data predict the microbiologic response to amphotericin B? Results of a prospective study of patients with Candida fungemia.

9 July 2018

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Clinical relevance of antifungal resistance

9 July 2018

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Combination therapy with amphotericin B and fluconazole against invasive candidiasis in neutropenic-mouse and infective-endocarditis rabbit models.

9 July 2018

1 reference

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Comparison of three different in vitro methods of detecting synergy: time-kill, checkerboard, and E test

9 July 2018

1 reference

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Fluconazole and amphotericin B antifungal susceptibility testing by National Committee for Clinical Laboratory Standards broth macrodilution method compared with E-test and semiautomated broth microdilution test

9 July 2018

1 reference

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Detection of candidal antigens in autoimmune polyglandular syndrome type I

9 July 2018

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Developmental changes in the expression of Leishmania chagasi gp63 and heat shock protein in a human macrophage cell line.

9 July 2018

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Demonstration of synergy with fluconazole and either ibuprofen, sodium salicylate, or propylparaben against Candida albicans in vitro

9 July 2018

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Isolation and characterization of a recombinant heat shock protein of Aspergillus fumigatus.

9 July 2018

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The expression of Candida albicans enolase is not heat shock inducible

9 July 2018

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Brugia malayi: the diagnostic potential of recombinant excretory/secretory antigens

9 July 2018

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Structure and regulation of the HSP90 gene from the pathogenic fungus Candida albicans

9 July 2018

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Activities of amphotericin B and antifungal azoles alone and in combination against Pseudallescheria boydii

9 July 2018

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In vitro evaluation of combination of fluconazole and flucytosine against Cryptococcus neoformans var. neoformans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Identification and molecular weight characterization of antigens from Candida albicans that are recognized by human sera

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Outbreak of systemic Candida albicans in intensive care unit caused by cross infection

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

The genome of Trypanosoma cruzi contains a constitutively expressed, tandemly arranged multicopy gene homologous to a major heat shock protein

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Isolation of immunodominant antigens from sera of patients with systemic candidiasis and characterization of serological response to Candida albicans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Characterisation and cellular localisation of the immunodominant 47-Kda antigen of Candida albicans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Molecular cloning of sequences encoding the human heat-shock proteins and their expression during hyperthermia

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Candida and AIDS: evidence for protective antibody

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Cloning of a DNA sequence encoding a major fragment of the 47 kilodalton stress protein homologue of Candida albicans

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Enolase activity associated with a C. albicans cytoplasmic antigen

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

The 86-kilodalton antigen from Schistosoma mansoni is a heat-shock protein homologous to yeast HSP-90.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Serologic analysis of antigen-specific reactivity in patients with systemic candidiasis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Detection of Candida antigenuria in disseminated candidiasis by immunoblotting

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Detection of circulating candida enolase by immunoassay in patients with cancer and invasive candidiasis

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Heat shock protein 88 and Aspergillus infection.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Nitric oxide: physiology, pathophysiology, and pharmacology

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

HSP 90, yeasts andCorynebacterium jeikeium

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Single chain antibody variable regions

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

A Method for Testing for Synergy with Any Number of Agents

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Increase in prevalence of nosocomial non-Candida albicans candidaemia and the association of Candida krusei with fluconazole use.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Comparison of Etest, chequerboard dilution and time-kill studies for the detection of synergy or antagonism between antifungal agents tested against Candida species

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Analysis of the serologic response to systemic Candida albicans infection in a murine model

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

A PCR-based approach to sequence the Candida tropicalis HSP90 gene

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Stress proteins in fungal diseases.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Karyotyping of Fluconazole-Resistant Yeasts with Phenotype Reported as Candida krusei or Candida inconspicua

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Immunogenicity and antigenicity of a Plasmodium falciparum protein fraction (90-110 kDa) able to protect squirrel monkeys against asexual blood stages.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Preliminary assessment of a human recombinant antibody fragment to hsp90 in murine invasive candidiasis.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Epitope mapping human heat shock protein 90 with sera from infected patients

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Detection of an antibody response in immunocompetent patients with systemic candidiasis or Candida albicans colonisation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

The Hsp90 of Candida albicans can confer Hsp90 functions in Saccharomyces cerevisiae: a potential model for the processes that generate immunogenic fragments of this molecular chaperone in C. albicans infections

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=161838

Autoantibodies to heat shock protein 90 in the human natural antibody repertoire

16 November 2018

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12 December 2020

A pharmacologic guide to the clinical use of amphotericin B

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12 December 2020

Immunoblot analysis of the serological response in systemic candidosis

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12 December 2020

Estrogen effects on Candida albicans: a potential virulence-regulating mechanism

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12 December 2020

Isolation and identification of a 92-kDa stress induced protein from Candida albicans

1 reference

12 December 2020

Expression of a cDNA encoding a Toxoplasma gondii protein belonging to the heat-shock 90 family and analysis of its antigenicity

1 reference

12 December 2020

The immunochemical characterisation of circulating immune complex constituents in Candida albicans osteomyelitis by isoelectric focusing, immunoblot, and immunoprint

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12 December 2020

Survival after rupture of the oesophagus and subsequent candidal endocarditis: use of new serological methods in management

1 reference

12 December 2020

The application of epitope mapping in the development of a new serological test for systemic candidosis

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12 December 2020

Autoantibody to heat-shock protein 90 can mediate protection against systemic candidosis

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12 December 2020

Western blot analysis of the immune response to Candida albicans antigens in 391 long-term intensive care patients

1 reference

12 December 2020

10.1128/AAC.47.7.2208-2216.2003

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference