Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta (Q35102957)

6 August 2017

title

Expression of the type-1 repeats of thrombospondin-1 inhibits tumor growth through activation of transforming growth factor-beta (English)

1 reference

6 August 2017

4

Michael Detmar

1 reference

6 August 2017

Karen O Yee

1

1 reference

6 August 2017

Michael Streit

series ordinal

2

1 reference

6 August 2017

Thomas Hawighorst

series ordinal

3

1 reference

6 August 2017

Jack Lawler

series ordinal

5

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 August 2004

1 reference

The American Journal of Pathology

6 August 2017

published in

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6 August 2017

volume

165

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6 August 2017

issue

2

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6 August 2017

page(s)

541-552

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Keratinocyte growth inhibition by high-dose epidermal growth factor is mediated by transforming growth factor beta autoinduction: a negative feedback mechanism for keratinocyte growth

6 August 2017

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Inhibition of angiogenesis by thrombospondin-1 is mediated by 2 independent regions within the type 1 repeats

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Overexpression of thrombospondin-1 decreases angiogenesis and inhibits the growth of human cutaneous squamous cell carcinomas

9 July 2018

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Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization

9 July 2018

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Active transforming growth factor-beta in wound repair: determination using a new assay

9 July 2018

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9 July 2018

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Thrombospondin-1 is a major activator of TGF-beta1 in vivo

9 July 2018

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A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1.

9 July 2018

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Decorin inhibits cell attachment to thrombospondin-1 by binding to a KKTR-dependent cell adhesive site present within the N-terminal domain of thrombospondin-1.

9 July 2018

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Thrombospondin-1 suppresses tumorigenesis and angiogenesis in serum- and anchorage-independent NIH 3T3 cells

9 July 2018

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CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells

9 July 2018

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Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis

9 July 2018

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Transforming growth factor-beta: vasculogenesis, angiogenesis, and vessel wall integrity

9 July 2018

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Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells

9 July 2018

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Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition

9 July 2018

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9 July 2018

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Thrombospondin modulates alpha v beta 3 function through integrin-associated protein

9 July 2018

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Tumor suppressor activity of the TGF-beta pathway in human cancers

9 July 2018

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9 July 2018

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9 July 2018

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Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity

9 July 2018

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Inhibition of capillary morphogenesis and associated apoptosis by dominant negative mutant transforming growth factor-beta receptors.

9 July 2018

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Diversity of function is inherent in matricellular proteins: an appraisal of thrombospondin 1

9 July 2018

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Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis.

9 July 2018

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Transforming growth factor-beta inhibits endothelial cell proliferation

9 July 2018

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Cell attachment to thrombospondin: the role of ARG-GLY-ASP, calcium, and integrin receptors

9 July 2018

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The properdin-like type I repeats of human thrombospondin contain a cell attachment site

9 July 2018

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Expression and mutagenesis of thrombospondin

9 July 2018

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Thrombospondin exerts an antiangiogenic effect on cord formation by endothelial cells in vitro

9 July 2018

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A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

9 July 2018

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Suppression of tumor-forming ability and related traits in MCF-7 human breast cancer cells by fusion with immortal mammary epithelial cells

9 July 2018

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Up-regulation of thrombospondin-1 gene by epidermal growth factor and transforming growth factor beta in human cancer cells--transcriptional activation and messenger RNA stabilization

9 July 2018

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Transgenic mice overexpressing a dominant-negative mutant type II transforming growth factor beta receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene

27 September 2018

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Mutant p53 correlates with reduced expression of thrombospondin-1, increased angiogenesis, and metastatic progression in melanoma

27 September 2018

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Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions

7 January 2021

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Downregulation of endothelial cell thrombospondin 1 enhances in vitro angiogenesis

7 January 2021

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The activation sequence of thrombospondin-1 interacts with the latency-associated peptide to regulate activation of latent transforming growth factor-beta

7 January 2021

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Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis

7 January 2021

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Transforming growth factor beta 1 induces apoptotic cell death in cultured human umbilical vein endothelial cells with down-regulated expression of bcl-2

7 January 2021

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Three distinct D-amino acid substitutions confer potent antiangiogenic activity on an inactive peptide derived from a thrombospondin-1 type 1 repeat

7 January 2021

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Thrombospondin-1 type 1 repeat recombinant proteins inhibit tumor growth through transforming growth factor-beta-dependent and -independent mechanisms

7 January 2021

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12 December 2020

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

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12 December 2020

Thrombospondin binds and activates the small and large forms of latent transforming growth factor-beta in a chemically defined system

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12 December 2020

The type 1 repeats of thrombospondin 1 activate latent transforming growth factor-beta

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12 December 2020

10.1016/S0002-9440(10)63319-6

Identifiers

DOI

1 reference

6 August 2017

1 reference

6 August 2017

1 reference