Nuclear lipid signalling (Q35120151)

6 August 2017

1 reference

title

Nuclear lipid signalling (English)

1 reference

6 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728269

30 December 2023

lipid metabolism

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728269

30 December 2023

1 reference

30 December 2023

author name string

Robin F. Irvine

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12728269

30 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12728269

30 December 2023

publication date

1 May 2003

1 reference

full work available at URL

6 August 2017

https://www.nature.com/articles/nrm1100.pdf

file format

Portable Document Format

1 reference

https://www.nature.com/articles/nrm1100

30 December 2023

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Nature Reviews Molecular Cell Biology

30 December 2023

published in

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6 August 2017

volume

4

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6 August 2017

issue

5

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6 August 2017

page(s)

349-360

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Phospholipid signalling in the nucleus. Een DAG uit het leven van de inositide signalering in de nucleus

6 August 2017

cites work

1 reference

Nuclear phospholipase C and signaling

31 March 2020

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Re-examination of the mechanisms regulating nuclear inositol lipid metabolism

31 March 2020

1 reference

31 March 2020

Nuclear lipid signaling

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Synthesis of polyphosphoinositides in nuclei of Friend cells. Evidence for polyphosphoinositide metabolism inside the nucleus which changes with cell differentiation

31 March 2020

1 reference

Rapid changes in phospholipid metabolism in the nuclei of Swiss 3T3 cells induced by treatment of the cells with insulin-like growth factor I.

31 March 2020

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The polyphosphoinositide cycle exists in the nuclei of Swiss 3T3 cells under the control of a receptor (for IGF-I) in the plasma membrane, and stimulation of the cycle increases nuclear diacylglycerol and apparently induces translocation of protein

31 March 2020

1 reference

Temporal changes in intracellular distribution of protein kinase C in Swiss 3T3 cells during mitogenic stimulation with insulin-like growth factor I and bombesin: translocation to the nucleus follows rapid changes in nuclear polyphosphoinositides

31 March 2020

1 reference

PIPkins1, their substrates and their products: new functions for old enzymes

31 March 2020

1 reference

Synthesis and function of 3-phosphorylated inositol lipids

31 March 2020

1 reference

Back in the water: the return of the inositol phosphates

31 March 2020

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Metabolism and possible compartmentalization of inositol lipids in isolated rat-liver nuclei

31 March 2020

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Phosphoinositides and calcium as regulators of cellular actin assembly and disassembly

31 March 2020

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The organization of replication and transcription

31 March 2020

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Searching for a function for nuclear actin.

31 March 2020

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Interphase nuclei of many mammalian cell types contain deep, dynamic, tubular membrane-bound invaginations of the nuclear envelope

31 March 2020

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Nuclear localization of enzymatically active green fluorescent protein-CTP:phosphocholine cytidylyltransferase alpha fusion protein is independent of cell cycle conditions and cell types

31 March 2020

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Highly saturated endonuclear phosphatidylcholine is synthesized in situ and colocated with CDP-choline pathway enzymes

31 March 2020

1 reference

A comparison of the molecular species compositions of mammalian lung surfactant phospholipids

31 March 2020

1 reference

Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors

31 March 2020

1 reference

Phospholipases in the nucleus

31 March 2020

1 reference

Nuclear localization and signalling activity of phosphoinositidase C beta in Swiss 3T3 cells

31 March 2020

1 reference

Phosphoinositide signalling enzymes in rat liver nuclei: phosphoinositidase C isoform beta 1 is specifically, but not predominantly, located in the nucleus

31 March 2020

1 reference

Phospholipase C gamma 1 is a physiological guanine nucleotide exchange factor for the nuclear GTPase PIKE

31 March 2020

1 reference

Regulation of phosphoinositide-specific phospholipase C isozymes

31 March 2020

1 reference

A role for nuclear phospholipase Cbeta 1 in cell cycle control

31 March 2020

1 reference

The role of carboxyl-terminal basic amino acids in Gqalpha-dependent activation, particulate association, and nuclear localization of phospholipase C-beta1.

31 March 2020

1 reference

Localization of two forms of phospholipase C-beta1, a and b, in C6Bu-1 cells.

31 March 2020

1 reference

The G-protein G(i) regulates mitosis but not DNA synthesis in growth factor-activated fibroblasts: a role for the nuclear translocation of G(i).

31 March 2020

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Insulin-like growth factor-I-dependent stimulation of nuclear phospholipase C-beta1 activity in Swiss 3T3 cells requires an intact cytoskeleton and is paralleled by increased phosphorylation of the phospholipase

31 March 2020

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Insulin selectively stimulates nuclear phosphoinositide-specific phospholipase C (PI-PLC) beta1 activity through a mitogen-activated protein (MAP) kinase-dependent serine phosphorylation.

31 March 2020

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Phosphorylation of nuclear phospholipase C beta1 by extracellular signal-regulated kinase mediates the mitogenic action of insulin-like growth factor I

31 March 2020

1 reference

Protein kinase C alpha -mediated negative feedback regulation is responsible for the termination of insulin-like growth factor I-induced activation of nuclear phospholipase C beta1 in Swiss 3T3 cells

31 March 2020

1 reference

Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells

31 March 2020

1 reference

Nuclear PLCbeta(1) acts as a negative regulator of p45/NF-E2 expression levels in Friend erythroleukemia cells

31 March 2020

1 reference

Cytoplasmic and nuclear phospholipase C-beta 1 relocation: role in resumption of meiosis in the mouse oocyte

31 March 2020

1 reference

Phospholipase C isozymes selectively couple to specific neurotransmitter receptors

31 March 2020

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Lamins: building blocks or regulators of gene expression?

31 March 2020

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A new phospholipase C delta 4 is induced at S-phase of the cell cycle and appears in the nucleus

31 March 2020

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Molecular cloning, splice variants, expression, and purification of phospholipase C-delta 4

31 March 2020

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A phospholipase C-dependent inositol polyphosphate kinase pathway required for efficient messenger RNA export

31 March 2020

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A role for nuclear inositol 1,4,5-trisphosphate kinase in transcriptional control

31 March 2020

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Modulation of ATP-dependent chromatin-remodeling complexes by inositol polyphosphates

31 March 2020

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Regulation of chromatin remodeling by inositol polyphosphates

31 March 2020

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Phospholipase C-delta1 contains a functional nuclear export signal sequence

31 March 2020

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Inositol trisphosphate, a novel second messenger in cellular signal transduction

31 March 2020

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Nuclei contain two differentially regulated pools of diacylglycerol

31 March 2020

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A role for nuclear phosphatidylinositol-specific phospholipase C in the G2/M phase transition

31 March 2020

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Nuclear diacylglycerol produced by phosphoinositide-specific phospholipase C is responsible for nuclear translocation of protein kinase C-alpha.

31 March 2020

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Proliferating or differentiating stimuli act on different lipid-dependent signaling pathways in nuclei of human leukemia cells.

31 March 2020

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Nuclear diacylglycerol is increased during cell proliferation in vivo

31 March 2020

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Phospholipids in the nucleus--metabolism and possible functions

31 March 2020

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betaII protein kinase C is required for the G2/M phase transition of cell cycle

31 March 2020

1 reference

Cytomegalovirus recruitment of cellular kinases to dissolve the nuclear lamina

31 March 2020

1 reference

Protein kinase C-beta II Is an apoptotic lamin kinase in polyomavirus-transformed, etoposide-treated pyF111 rat fibroblasts

31 March 2020

1 reference

Increase in nuclear phosphatidylinositol 3-kinase activity and phosphatidylinositol (3,4,5) trisphosphate synthesis precede PKC-zeta translocation to the nucleus of NGF-treated PC12 cells

31 March 2020

1 reference

Molecular characterization of protein kinase C-alpha binding to lamin A.

31 March 2020

1 reference

Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localizes in neurons

31 March 2020

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Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling

31 March 2020

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Phosphatidylinositol 4,5-bisphosphate reverses the inhibition of RNA transcription caused by histone H1.

31 March 2020

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Phosphoinositide 3-kinase in rat liver nuclei

31 March 2020

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Agonists cause nuclear translocation of phosphatidylinositol 3-kinase gamma. A Gbetagamma-dependent pathway that requires the p110gamma amino terminus

31 March 2020

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Characterization of a G protein-activated phosphoinositide 3-kinase in vascular smooth muscle cell nuclei

31 March 2020

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A role for nuclear PTEN in neuronal differentiation.

31 March 2020

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Differential nuclear and cytoplasmic expression of PTEN in normal thyroid tissue, and benign and malignant epithelial thyroid tumors

31 March 2020

1 reference

Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N

31 March 2020

1 reference

Phosphatidylinositol 3-kinase c2alpha contains a nuclear localization sequence and associates with nuclear speckles

31 March 2020

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Presence and activation of nuclear phosphoinositide 3-kinase C2beta during compensatory liver growth

31 March 2020

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The activation of nuclear phosphoinositide 3-kinase C2beta in all-trans-retinoic acid-differentiated HL-60 cells

31 March 2020

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Evidence that 3'-phosphorylated polyphosphoinositides are generated at the nuclear surface: use of immunostaining technique with monoclonal antibodies specific for PI 3,4-P(2).

31 March 2020

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Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

31 March 2020

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Association of phosphatidylinositol 3-kinase with nuclear transcription sites in higher plants.

31 March 2020

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Evidence that a phosphatidylinositol 3,4,5-trisphosphate-binding protein can function in nucleus

31 March 2020

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The nuclear phosphoinositide 3-kinase/AKT pathway: a new second messenger system.

31 March 2020

1 reference

Translocation of the 85-kDa phospholipase A2 from cytosol to the nuclear envelope in rat basophilic leukemia cells stimulated with calcium ionophore or IgE/antigen

31 March 2020

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Calcium-mediated translocation of cytosolic phospholipase A2 to the nuclear envelope and endoplasmic reticulum

31 March 2020

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Translocation of cytosolic phospholipase A2 to the nuclear envelope elicits topographically localized phospholipid hydrolysis

31 March 2020

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Nuclear localization of prostaglandin E2 receptors

31 March 2020

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A novel phospholipase A2 associated with nuclear matrix: stimulation of the activity and modulation of the Ca2+ dependency by polyphosphoinositides

31 March 2020

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Co-localization of leukotriene a4 hydrolase with 5-lipoxygenase in nuclei of alveolar macrophages and rat basophilic leukemia cells but not neutrophils

31 March 2020

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Prostaglandins and leukotrienes: advances in eicosanoid biology

31 March 2020

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Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARgamma agonist

31 March 2020

1 reference

Alpha-thrombin-induced nuclear sn-1,2-diacylglycerols are derived from phosphatidylcholine hydrolysis in cultured fibroblasts

31 March 2020

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Phosphatidylglycerol is a physiologic activator of nuclear protein kinase C

31 March 2020

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Mapping of a molecular determinant for protein kinase C betaII isozyme function

31 March 2020

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Phospholipid interactions in rat liver nuclear matrix

31 March 2020

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Existence of Mg2+-dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells

31 March 2020

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A possible role of nuclear ceramide and sphingosine in hepatocyte apoptosis in rat liver

31 March 2020

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Sphingosine inhibits the synthesis of RNA primers by primase in vitro

31 March 2020

1 reference

Fluorescently labeled phosphatidylinositol transfer protein isoforms (alpha and beta), microinjected into fetal bovine heart endothelial cells, are targeted to distinct intracellular sites

31 March 2020

1 reference

Phosphoinositide signalling in nuclei of Friend cells: DMSO-induced differentiation reduces the association of phosphatidylinositol-transfer protein with the nucleus

31 March 2020

1 reference

Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils

31 March 2020

1 reference

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate

31 March 2020

1 reference

Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells

31 March 2020

1 reference

Mechanisms controlling gene expression by nuclear calcium signals.

31 March 2020

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"Tell me where is calcium bred": clarifying the roles of nuclear calcium

31 March 2020

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Nuclear calcium signalling

31 March 2020

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ATP-dependent accumulation and inositol trisphosphate- or cyclic ADP-ribose-mediated release of Ca2+ from the nuclear envelope

31 March 2020

1 reference

Novel biochemical and functional insights into nuclear Ca(2+) transport through IP(3)Rs and RyRs in osteoblasts

31 March 2020

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Changes in either cytosolic or nucleoplasmic inositol 1,4,5-trisphosphate levels can control nuclear Ca2+ concentration

31 March 2020

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Effects of 1-methyladenine on nuclear Ca2+ transients and meiosis resumption in starfish oocytes are mimicked by the nuclear injection of inositol 1,4,5-trisphosphate and cADP-ribose

31 March 2020

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Separate activation of the cytoplasmic and nuclear calcium pools in maturing starfish oocytes

31 March 2020

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Spatiotemporal analysis of calcium dynamics in the nucleus of hamster oocytes

31 March 2020

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Nuclear calcium signalling by individual cytoplasmic calcium puffs

31 March 2020

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Protein kinase C regulates the nuclear localization of diacylglycerol kinase-zeta

31 March 2020

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Translocation of diacylglycerol kinase α to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes

31 March 2020

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Nuclear diacylglycerol kinase-theta is activated in response to alpha-thrombin

31 March 2020

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Diacylglycerol kinases in nuclear lipid-dependent signal transduction pathways

31 March 2020

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Remodelling the walls of the nucleus

31 March 2020

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A novel pathway of cellular phosphatidylinositol(3,4,5)-trisphosphate synthesis is regulated by oxidative stress

31 March 2020

1 reference

Biochimica et Biophysica Acta

31 March 2020

5

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A Martelli

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30 December 2023

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CD Smith

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30 December 2023

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30 December 2023

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1997

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30 December 2023

129

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AM Martelli

2000

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30 December 2023

Identifiers

DOI

10.1038/NRM1100

1 reference

6 August 2017

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