In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer (Q35168034)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704006%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

In vivo and in vitro evidence that PPARγ ligands are antagonists of leptin signaling in breast cancer (English)

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5 February 2020

1

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5 February 2020

Daniela Bonofiglio

3

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5 February 2020

Michele Pellegrino

4

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5 February 2020

Pietro Rizza

6

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5 February 2020

Gianluca Bossi

8

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5 February 2020

author name string

Loredana Mauro

2

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5 February 2020

Hongyan Qi

5

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5 February 2020

Donatella Vizza

7

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5 February 2020

Sebastiano Andò

9

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5 February 2020

language of work or name

English

0 references

publication date

23 June 2011

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704006%20AND%20SRC:MED&resulttype=core&format=json

The American Journal of Pathology

5 February 2020

published in

1 reference

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5 February 2020

volume

179

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5 February 2020

issue

2

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page(s)

1030-1040

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Cooperative NCoR/SMRT interactions establish a corepressor-based strategy for integration of inflammatory and anti-inflammatory signaling pathways

5 February 2020

cites work

1 reference

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Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling

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Altering PPARgamma ligand selectivity impairs adipogenesis by thiazolidinediones but not hormonal inducers

13 July 2018

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13 July 2018

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13 July 2018

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DAX-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X-chromosome, gene 1) selectively inhibits transactivation but not transrepression mediated by the glucocorticoid receptor in a LXXLL-dependent manner.

13 July 2018

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Peroxisome proliferator-activated receptor gamma activates fas ligand gene promoter inducing apoptosis in human breast cancer cells

13 July 2018

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13 July 2018

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Insulin-like growth factor-I, regulating aromatase expression through steroidogenic factor 1, supports estrogen-dependent tumor Leydig cell proliferation.

13 July 2018

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Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression

13 July 2018

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PPARs and molecular mechanisms of transrepression

13 July 2018

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A peroxisome-proliferator activated receptor-gamma ligand could regulate the expression of leptin receptor on human hepatic stellate cells

13 July 2018

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Nuclear Receptor Cofactors in PPARgamma-Mediated Adipogenesis and Adipocyte Energy Metabolism

13 July 2018

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Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells

13 July 2018

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Nuclear receptor corepressors and PPARgamma

13 July 2018

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13 July 2018

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Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway.

13 July 2018

1 reference

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Differential regulation of chemokine expression by peroxisome proliferator-activated receptor gamma agonists: interactions with glucocorticoids and beta2-agonists

13 July 2018

1 reference

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IGF-I receptor, cell-cell adhesion, tumour development and progression

13 July 2018

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Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells.

13 July 2018

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Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line

13 July 2018

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Leptin induces endothelial cell migration through Akt, which is inhibited by PPARgamma-ligands

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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A dominant-negative peroxisome proliferator-activated receptor gamma (PPARgamma) mutant is a constitutive repressor and inhibits PPARgamma-mediated adipogenesis

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Activators of the nuclear receptor PPARgamma enhance colon polyp formation

13 July 2018

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Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

13 July 2018

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Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma

13 July 2018

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Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes

13 July 2018

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13 July 2018

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13 July 2018

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13 July 2018

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Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells

27 September 2018

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Biomedicine. Defining the "S" in SERMs

27 September 2018

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27 September 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21704006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Activation of the peroxisome proliferator-activated receptor γ promotes the development of colon tumors in C57BL/6J-APCMin/+ mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21704006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.AJPATH.2011.04.026

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704006%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21704006%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

21704006

1 reference