Tumor formation by genetic mutations in the components of the Wnt signaling pathway (Q35161748)

6 August 2017

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title

Tumor formation by genetic mutations in the components of the Wnt signaling pathway (English)

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6 August 2017

Akira Kikuchi

1

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6 August 2017

publication date

1 March 2003

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6 August 2017

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6 August 2017

volume

94

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6 August 2017

issue

3

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6 August 2017

page(s)

225-229

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Mechanisms of Wnt signaling in development

6 August 2017

cites work

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Roles of Axin in the Wnt signalling pathway

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

The LDL receptor gene family: signaling functions during development.

21 January 2018

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T-cell factors: turn-ons and turn-offs

21 January 2018

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The ubiquitin-proteasome pathway: on protein death and cell life

21 January 2018

1 reference

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Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Siah-1 mediates a novel beta-catenin degradation pathway linking p53 to the adenomatous polyposis coli protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activity

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

The C-terminal domain of armadillo binds to hypophosphorylated teashirt to modulate wingless signalling in Drosophila

21 January 2018

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APC, signal transduction and genetic instability in colorectal cancer

21 January 2018

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Asef, a link between the tumor suppressor APC and G-protein signaling

21 January 2018

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Identification of a link between the tumour suppressor APC and the kinesin superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Down-regulation of beta-catenin by the colorectal tumor suppressor APC requires association with Axin and beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Complex formation of adenomatous polyposis coli gene product and axin facilitates glycogen synthase kinase-3 beta-dependent phosphorylation of beta-catenin and down-regulates beta-catenin.

21 January 2018

1 reference

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The adenomatous polyposis coli tumor suppressor protein localizes to plasma membrane sites involved in active cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Axin prevents Wnt-3a-induced accumulation of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Synergistic activation of the Wnt signaling pathway by Dvl and casein kinase Iepsilon

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Physiological regulation of [beta]-catenin stability by Tcf3 and CK1epsilon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

The DIX domain targets dishevelled to actin stress fibres and vesicular membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1349-7006.2003.TB01424.X

10.1111/J.1349-7006.2003.TB01424.X

21 January 2018

Identifiers

DOI

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6 August 2017

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