Regulation of Tiam1-Rac signalling. (Q35163913)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829230%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

review article

1 reference

title

Regulation of Tiam1-Rac signalling (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829230%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

2

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5 November 2019

author name string

Alexander E Mertens

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829230%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

John G Collard

series ordinal

3

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5 November 2019

language of work or name

English

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publication date

1 July 2003

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5 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12829230%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

volume

546

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5 November 2019

issue

1

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5 November 2019

page(s)

11-16

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5 November 2019

cites work

RHO-GTPases and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

A role for Rho in Ras transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

A role for Rac in Tiam1-induced membrane ruffling and invasion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Regulated membrane localization of Tiam1, mediated by the NH2-terminal pleckstrin homology domain, is required for Rac-dependent membrane ruffling and C-Jun NH2-terminal kinase activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Targeting of Tiam1 to the plasma membrane requires the cooperative function of the N-terminal pleckstrin homology domain and an adjacent protein interaction domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Tiam1 mediates Ras activation of Rac by a PI(3)K-independent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Regulation of proto-Dbl by intracellular membrane targeting and protein stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Ras binding triggers ubiquitination of the Ras exchange factor Ras-GRF2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Tiam1 mutations in human renal-cell carcinomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Dissociation of GDP dissociation inhibitor and membrane translocation are required for efficient activation of Rac by the Dbl homology-pleckstrin homology region of Tiam

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Rac activation by lysophosphatidic acid LPA1 receptors through the guanine nucleotide exchange factor Tiam1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Translocation of the Rac1 guanine nucleotide exchange factor Tiam1 induced by platelet-derived growth factor and lysophosphatidic acid

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

PIP3, PIP2, and cell movement--similar messages, different meanings?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Pleckstrin homology domains and the cytoskeleton

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

An essential role for Rac in Ras transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Tiam1 overexpression potentiates heregulin-induced lymphoid enhancer factor-1/beta -catenin nuclear signaling in breast cancer cells by modulating the intercellular stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Oncogenic Ras downregulates Rac activity, which leads to increased Rho activity and epithelial-mesenchymal transition

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Inhibition of invasion of epithelial cells by Tiam1-Rac signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

CD44 interaction with tiam1 promotes Rac1 signaling and hyaluronic acid-mediated breast tumor cell migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

The neuronal actin-binding proteins, neurabin I and neurabin II, recruit specific isoforms of protein phosphatase-1 catalytic subunits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Guanine nucleotide exchange factor, Tiam1, directly binds to c-Myc and interferes with c-Myc-mediated apoptosis in rat-1 fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6

Coiled coils: a highly versatile protein folding motif

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-5793%2803%2900435-6