Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis (Q35183953)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25664849%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis (English)

1 reference

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29 February 2020

1 reference

1

1 reference

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29 February 2020

Akash K Kaushik

6

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29 February 2020

17

Bert W O'Malley

1 reference

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29 February 2020

author name string

Nagireddy Putluri

2

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29 February 2020

Weiwen Long

3

1 reference

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29 February 2020

Bin Zhang

4

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29 February 2020

Jianghua Wang

5

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29 February 2020

James M Arnold

7

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29 February 2020

Salil K Bhowmik

8

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29 February 2020

Erin Stashi

9

1 reference

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29 February 2020

Christine A Brennan

10

1 reference

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29 February 2020

Kimal Rajapakshe

11

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29 February 2020

Cristian Coarfa

12

1 reference

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29 February 2020

Nicholas Mitsiades

13

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29 February 2020

Michael M Ittmann

14

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29 February 2020

Arul M Chinnaiyan

15

1 reference

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29 February 2020

Arun Sreekumar

16

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29 February 2020

language of work or name

English

0 references

publication date

9 February 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25664849%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

29 February 2020

published in

1 reference

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29 February 2020

volume

125

1 reference

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29 February 2020

issue

3

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29 February 2020

page(s)

1174-1188

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Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology

29 February 2020

cites work

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SRC-2 is an essential coactivator for orchestrating metabolism and circadian rhythm

13 July 2018

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13 July 2018

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13 July 2018

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Metformin decreases glucose oxidation and increases the dependency of prostate cancer cells on reductive glutamine metabolism.

13 July 2018

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13 July 2018

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The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4

13 July 2018

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The fat side of prostate cancer

13 July 2018

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SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism

13 July 2018

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In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation

13 July 2018

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Human castration resistant prostate cancer rather prefer to decreased 5α-reductase activity

13 July 2018

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Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.

13 July 2018

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Cancer cell metabolism: one hallmark, many faces.

13 July 2018

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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells

13 July 2018

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Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

13 July 2018

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Oncogenic activation in prostate cancer progression and metastasis: Molecular insights and future challenges

13 July 2018

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Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia

13 July 2018

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Reductive carboxylation supports growth in tumour cells with defective mitochondria.

13 July 2018

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mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

13 July 2018

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Metabolomic profiling reveals a role for androgen in activating amino acid metabolism and methylation in prostate cancer cells

13 July 2018

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Phosphoproteomic profiling of in vivo signaling in liver by the mammalian target of rapamycin complex 1 (mTORC1)

13 July 2018

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The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling.

13 July 2018

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Hallmarks of Cancer: The Next Generation

13 July 2018

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Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.

13 July 2018

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The transcriptional coregulators TIF2 and SRC-1 regulate energy homeostasis by modulating mitochondrial respiration in skeletal muscles

13 July 2018

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Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

13 July 2018

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Integrative genomic profiling of human prostate cancer

13 July 2018

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Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif.

13 July 2018

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

13 July 2018

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c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

13 July 2018

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Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

13 July 2018

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13 July 2018

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Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease

13 July 2018

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Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

13 July 2018

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Transcriptional regulation of the major zinc uptake protein hZip1 in prostate cancer cells

13 July 2018

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Multi-modulation of nuclear receptor coactivators through posttranslational modifications

13 July 2018

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Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line

13 July 2018

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Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

13 July 2018

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Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

13 July 2018

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A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth

13 July 2018

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Androgens modulate expression of transcription intermediary factor 2, an androgen receptor coactivator whose expression level correlates with early biochemical recurrence in prostate cancer

13 July 2018

1 reference

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Mitochondrial aconitase and citrate metabolism in malignant and nonmalignant human prostate tissues

13 July 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

13 July 2018

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Lineage relationship between LNCaP and LNCaP-derived prostate cancer cell lines

13 July 2018

1 reference

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Fatty acid synthase expression defines distinct molecular signatures in prostate cancer.

13 July 2018

1 reference

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The function of TIF2/GRIP1 in mouse reproduction is distinct from those of SRC-1 and p/CIP.

13 July 2018

1 reference

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Nutritional and insulin regulation of fatty acid synthetase and leptin gene expression through ADD1/SREBP1.

13 July 2018

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Glutaminolysis activates Rag-mTORC1 signaling.

13 July 2018

1 reference

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Comparison of [18 F]fluorocholine and [18 F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer

27 September 2018

1 reference

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SRC-1 and TIF2 control energy balance between white and brown adipose tissues

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25664849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Zinc inhibition of mitochondrial aconitase and its importance in citrate metabolism of prostate epithelial cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25664849

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI76029

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25664849%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25664849%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

PubMed publication ID

25664849

1 reference