Determinants of specificity in TGF-beta signal transduction. (Q35205890)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9679059%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

title

Determinants of specificity in TGF-beta signal transduction (English)

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13 November 2019

4

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13 November 2019

Joan Massagué Solé

7

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13 November 2019

author name string

Y G Chen

1

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13 November 2019

A Hata

2

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13 November 2019

R S Lo

3

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13 November 2019

Y Shi

5

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13 November 2019

N Pavletich

6

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13 November 2019

publication date

1 July 1998

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13 November 2019

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13 November 2019

volume

12

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13 November 2019

issue

14

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13 November 2019

page(s)

2144-2152

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TGF-beta signal transduction

13 November 2019

cites work

1 reference

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The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

13 July 2018

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Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

13 July 2018

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Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads

13 July 2018

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Signaling through scaffold, anchoring, and adaptor proteins

13 July 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

13 July 2018

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Dual role of the Smad4/DPC4 tumor suppressor in TGFbeta-inducible transcriptional complexes

13 July 2018

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Smad8 mediates the signaling of the ALK-2 [corrected] receptor serine kinase

13 July 2018

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

13 July 2018

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

13 July 2018

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Smad4 and FAST-1 in the assembly of activin-responsive factor

13 July 2018

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A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity

13 July 2018

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Mechanism of TGFbeta receptor inhibition by FKBP12

13 July 2018

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Bone morphogenetic proteins in the nervous system

13 July 2018

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A structural basis for mutational inactivation of the tumour suppressor Smad4

13 July 2018

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Mutations increasing autoinhibition inactivate tumour suppressors Smad2 and Smad4

13 July 2018

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The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

13 July 2018

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Smad5 induces ventral fates in Xenopus embryo

13 July 2018

1 reference

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

13 July 2018

1 reference

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

13 July 2018

1 reference

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Transcriptional regulation by transforming growth factor beta of the expression of retinoic acid and retinoid X receptor genes in osteoblastic cells is mediated through AP-1.

13 July 2018

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

13 July 2018

1 reference

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A transcriptional partner for MAD proteins in TGF-beta signalling

13 July 2018

1 reference

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Identification of a potential regulator of early transcriptional responses to mesoderm inducers in the frog embryo.

13 July 2018

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Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth

13 July 2018

1 reference

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Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

13 July 2018

1 reference

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Bone morphogenetic proteins: multifunctional regulators of vertebrate development

13 July 2018

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13 July 2018

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A human Mad protein acting as a BMP-regulated transcriptional activator

13 July 2018

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Complementation between kinase-defective and activation-defective TGF-beta receptors reveals a novel form of receptor cooperativity essential for signaling.

13 July 2018

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Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components

13 July 2018

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

13 July 2018

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The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

13 July 2018

1 reference

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Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

13 July 2018

1 reference

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Characterization of type I receptors for transforming growth factor-beta and activin

13 July 2018

1 reference

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Mechanism of activation of the TGF-beta receptor

13 July 2018

1 reference

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Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

13 July 2018

1 reference

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GS domain mutations that constitutively activate T beta R-I, the downstream signaling component in the TGF-beta receptor complex

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Activins and the receptor serine kinase superfamily

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

The transforming growth factor-beta family

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Distinct transforming growth factor-beta (TGF-beta) receptor subsets as determinants of cellular responsiveness to three TGF-beta isoforms.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Structural framework for the protein kinase family

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

TGF beta signals through a heteromeric protein kinase receptor complex

13 July 2018

1 reference

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A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=317013

Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers.

26 September 2018

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Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily

26 September 2018

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26 September 2018

Identifiers

DOI

10.1101/GAD.12.14.2144

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13 November 2019

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13 November 2019

PubMed publication ID

9679059

1 reference