Astrocytes from familial and sporadic ALS patients are toxic to motor neurons (Q35206666)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832997%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

title

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons (English)

1 reference

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amyotrophic lateral sclerosis

10 February 2020

main subject

astrocyte

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1 reference

16

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10 February 2020

author name string

Amanda M Haidet-Phillips

1

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10 February 2020

Mark E Hester

2

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10 February 2020

Carlos J Miranda

3

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10 February 2020

Kathrin Meyer

4

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10 February 2020

Lyndsey Braun

5

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10 February 2020

Ashley Frakes

6

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10 February 2020

SungWon Song

7

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10 February 2020

Shibi Likhite

8

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10 February 2020

Matthew J Murtha

9

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10 February 2020

Kevin D Foust

10

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10 February 2020

Meghan Rao

11

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10 February 2020

Amy Eagle

12

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10 February 2020

Anja Kammesheidt

13

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10 February 2020

Ashley Christensen

14

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10 February 2020

Jerry R Mendell

15

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10 February 2020

Brian K Kaspar

17

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10 February 2020

publication date

10 August 2011

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10 February 2020

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10 February 2020

volume

29

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10 February 2020

issue

9

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10 February 2020

page(s)

824-828

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Rapid and efficient generation of functional motor neurons from human pluripotent stem cells using gene delivered transcription factor codes.

10 February 2020

cites work

1 reference

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Proteins that bind to misfolded mutant superoxide dismutase-1 in spinal cords from transgenic amyotrophic lateral sclerosis (ALS) model mice

28 July 2018

1 reference

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Activation of interferon signaling pathways in spinal cord astrocytes from an ALS mouse model

28 July 2018

1 reference

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A functionally characterized test set of human induced pluripotent stem cells

28 July 2018

1 reference

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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

28 July 2018

1 reference

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AAV4-mediated Expression of IGF-1 and VEGF Within Cellular Components of the Ventricular System Improves Survival Outcome in Familial ALS Mice

28 July 2018

1 reference

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Mechanisms underlying inflammation in neurodegeneration

28 July 2018

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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

28 July 2018

1 reference

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Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

28 July 2018

1 reference

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Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

28 July 2018

1 reference

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Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis

28 July 2018

1 reference

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ALS: a disease of motor neurons and their nonneuronal neighbors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Inter- and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase

28 July 2018

1 reference

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Onset and progression in inherited ALS determined by motor neurons and microglia

28 July 2018

1 reference

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Directed differentiation of embryonic stem cells into motor neurons

28 July 2018

1 reference

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Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

28 July 2018

1 reference

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Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

26 September 2018

1 reference

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Common molecular signature in SOD1 for both sporadic and familial amyotrophic lateral sclerosis.

26 September 2018

1 reference

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Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model

26 September 2018

1 reference

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Differential properties of adult rat and mouse brain-derived neural stem/progenitor cells

26 September 2018

1 reference

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Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis

26 September 2018

1 reference

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Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3170425

Cell culture. Progenitor cells from human brain after death

26 September 2018

1 reference

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Amyotrophic lateral sclerosis. Insights from genetics

26 September 2018

1 reference

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26 September 2018

Identifiers

DOI

10.1038/NBT.1957

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21832997%20AND%20SRC:MED&resulttype=core&format=json

10 February 2020

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10 February 2020

PubMed publication ID

21832997

1 reference