Aromatic lipophilic spin traps effectively inhibit RPE65 isomerohydrolase activity (Q35203590)

7 August 2017

title

Aromatic lipophilic spin traps effectively inhibit RPE65 isomerohydrolase activity (English)

1 reference

7 August 2017

Eugenia Poliakov

1

1 reference

7 August 2017

Toral Parikh

2

1 reference

7 August 2017

Michael Ayele

3

1 reference

7 August 2017

Stephanie Kuo

4

1 reference

7 August 2017

Preethi Chander

5

1 reference

7 August 2017

Susan Gentleman

6

1 reference

7 August 2017

T Michael Redmond

7

1 reference

7 August 2017

language of work or name

English

0 references

publication date

13 July 2011

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7 August 2017

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7 August 2017

volume

50

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7 August 2017

issue

32

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7 August 2017

page(s)

6739-6741

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An enzymatic mechanism for generating the precursor of endogenous 13-cis retinoic acid in the brain

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

RPE65, visual cycle retinol isomerase, is not inherently 11-cis-specific: support for a carbocation mechanism of retinol isomerization

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Crystal structure of native RPE65, the retinoid isomerase of the visual cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

RPE65 is the isomerohydrolase in the retinoid visual cycle

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Pharmacological effects of the spin trap agents N-t-butyl-phenylnitrone (PBN) and 2,2,6, 6-tetramethylpiperidine-N-oxyl (TEMPO) in a rabbit thromboembolic stroke model: combination studies with the thrombolytic tissue plasminogen activator

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Mutations in the RPE65 gene in patients with autosomal recessive retinitis pigmentosa or leber congenital amaurosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Mutations in RPE65 cause autosomal recessive childhood-onset severe retinal dystrophy

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Mutations in RPE65 cause Leber's congenital amaurosis

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II Trials

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Systemic administration of phenyl-N-tert-butylnitrone protects the retina from light damage.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

The Rpe65 Leu450Met variation increases retinal resistance against light-induced degeneration by slowing rhodopsin regeneration.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Isomerization of all-trans-retinol to cis-retinols in bovine retinal pigment epithelial cells: dependence on the specificity of retinoid-binding proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3169428

EPR spin trapping detection of carbon-centered carotenoid and beta-ionone radicals

26 September 2018

1 reference

12 December 2020

Detection of some retinoid radicals using high-performance liquid chromatography with electron spin resonance spectroscopy or electrochemical detection

1 reference

12 December 2020

Stereochemical inversion at C-15 accompanies the enzymatic isomerization of all-trans- to 11-cis-retinoids

1 reference

12 December 2020

In vivo EPR studies of the metabolic fate of nitrosobenzene in the mouse

1 reference

12 December 2020

Cytotoxicity of spin trapping compounds

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI200532M

1 reference

release_vijhtbinfrghfdkxxwsgxiqcki

7 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/vijhtbinfrghfdkxxwsgxiqcki

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3169428

1 reference

7 August 2017

1 reference