Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection (Q35217462)

7 August 2017

title

Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection (English)

1 reference

7 August 2017

Alissa A Chackerian

1

1 reference

7 August 2017

Shi-Juan Chen

2

1 reference

7 August 2017

Scott J Brodie

3

1 reference

7 August 2017

Jeanine D Mattson

4

1 reference

7 August 2017

Terrill K McClanahan

5

1 reference

7 August 2017

Robert A Kastelein

6

1 reference

7 August 2017

Edward P Bowman

7

1 reference

7 August 2017

language of work or name

English

0 references

publication date

21 August 2006

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7 August 2017

published in

Infection and Immunity

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7 August 2017

volume

74

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7 August 2017

issue

11

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7 August 2017

page(s)

6092-6099

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Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

7 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Pulmonary interleukin-23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

The role of interleukin-12 in human infectious diseases: only a faint signature

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

In vivo clearance of an intracellular bacterium, Francisella tularensis LVS, is dependent on the p40 subunit of interleukin-12 (IL-12) but not on IL-12 p70.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Ubiquitous transgenic expression of the IL-23 subunit p19 induces multiorgan inflammation, runting, infertility, and premature death

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Acquired resistance but not innate resistance to Mycobacterium bovis bacillus Calmette-Guérin is compromised by interleukin-12 ablation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Interleukin-12 is essential for a protective Th1 response in mice infected with Cryptococcus neoformans

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

The inducing role of tumor necrosis factor in the development of bactericidal granulomas during BCG infection

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Interleukin-12p40 mediates transient protection against Mycobacterium avium infection in the absence of interleukin-12.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Severe CD4 T cell-mediated immunopathology in murine schistosomiasis is dependent on IL-12p40 and correlates with high levels of IL-17.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

IL-23 provides a limited mechanism of resistance to acute toxoplasmosis in the absence of IL-12.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Granulomatous infectious diseases associated with tumor necrosis factor antagonists

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Mice lacking bioactive IL-12 can generate protective, antigen-specific cellular responses to mycobacterial infection only if the IL-12 p40 subunit is present

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

A protective and agonistic function of IL-12p40 in mycobacterial infection.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

IL-12p40-dependent agonistic effects on the development of protective innate and adaptive immunity against Salmonella enteritidis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1695481

Cutting edge: IFN-gamma regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16923792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16923792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16923792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/IAI.00621-06

1 reference

7 August 2017

1 reference

7 August 2017

1 reference