Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones (Q35242884)

7 August 2017

title

Muscle-specific PPARgamma-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones (English)

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7 August 2017

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5

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7 August 2017

Andrew W Norris

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Bruce Spiegelman

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object named as

Bruce M Spiegelman

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7 August 2017

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C Ronald Kahn

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8

Evan D Rosen

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7 August 2017

Lihong Chen

2

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7 August 2017

Simon J Fisher

3

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7 August 2017

Ildiko Szanto

4

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7 August 2017

Alison C Jozsi

6

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7 August 2017

Michael F Hirshman

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7 August 2017

Laurie J Goodyear

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7 August 2017

Frank J Gonzalez

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7 August 2017

language of work or name

English

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publication date

1 August 2003

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Journal of Clinical Investigation

7 August 2017

published in

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7 August 2017

volume

112

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7 August 2017

issue

4

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7 August 2017

page(s)

608-618

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describes a project that uses

7 August 2017

ImageQuant

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC171387/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Loss of the peroxisome proliferation-activated receptor gamma (PPARgamma ) does not affect mammary development and propensity for tumor formation but leads to reduced fertility

26 September 2018

1 reference

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PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein

26 September 2018

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Peroxisome proliferator-activated receptor (PPAR) gamma and retinoid X receptor (RXR) agonists have complementary effects on glucose and lipid metabolism in human skeletal muscle

26 September 2018

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Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation

26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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26 September 2018

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A potent in vivo effect of ciglitazone on muscle insulin resistance induced by high fat feeding of rats

26 September 2018

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The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

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Effect of dietary fat content on the incidence of obesity among ad libitum fed mice

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Monoamine oxidase activities in dissociated cell fractions from rat skeletal muscle

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Myogenicity in vitro and in vivo of mouse muscle cells separated on discontinuous Percoll gradients

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Role of glucose and insulin resistance in development of type 2 diabetes mellitus: results of a 25-year follow-up study

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A moderate decline in specific activity does not lead to an underestimation of hepatic glucose production during a glucose clamp

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A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

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Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase

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Mechanism of troglitazone action in type 2 diabetes

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Expression of genes involved in lipid metabolism correlate with peroxisome proliferator-activated receptor gamma expression in human skeletal muscle

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Impaired oxidation of plasma-derived fatty acids in type 2 diabetic subjects during moderate-intensity exercise

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The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance

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12 December 2020

Identifiers

DOI

10.1172/JCI17305

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7 August 2017

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7 August 2017

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