The liver kinase B1 is a central regulator of T cell development, activation, and metabolism (Q35500559)

8 August 2017

title

The liver kinase B1 is a central regulator of T cell development, activation, and metabolism (English)

1 reference

8 August 2017

Nancie J MacIver

1

1 reference

8 August 2017

Julianna Blagih

2

1 reference

8 August 2017

Donte C Saucillo

3

1 reference

8 August 2017

Luciana Tonelli

4

1 reference

8 August 2017

Takla Griss

5

1 reference

8 August 2017

Jeffrey C Rathmell

6

1 reference

8 August 2017

Russell G Jones

7

1 reference

8 August 2017

language of work or name

English

0 references

publication date

19 September 2011

1 reference

8 August 2017

published in

Journal of Immunology

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8 August 2017

volume

187

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8 August 2017

issue

8

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8 August 2017

page(s)

4187-4198

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Regulation of T-cell survival and mitochondrial homeostasis by TSC1

8 August 2017

cites work

1 reference

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The proapoptotic factors Bax and Bak regulate T Cell proliferation through control of endoplasmic reticulum Ca(2+) homeostasis

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase

12 July 2018

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12 July 2018

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LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1

12 July 2018

1 reference

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TSC2 mediates cellular energy response to control cell growth and survival

12 July 2018

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

12 July 2018

1 reference

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Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

12 July 2018

1 reference

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The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

12 July 2018

1 reference

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

12 July 2018

1 reference

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The CD28 signaling pathway regulates glucose metabolism

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1).

12 July 2018

1 reference

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Signaling takes a breath--new quantitative perspectives on bioenergetics and signal transduction.

12 July 2018

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Akt and Bcl-xL promote growth factor-independent survival through distinct effects on mitochondrial physiology

12 July 2018

1 reference

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In the absence of extrinsic signals, nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability

12 July 2018

1 reference

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A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

12 July 2018

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

12 July 2018

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The mTOR kinase determines effector versus memory CD8+ T cell fate by regulating the expression of transcription factors T-bet and Eomesodermin

12 July 2018

1 reference

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AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function

26 September 2018

1 reference

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Revving the engine: signal transduction fuels T cell activation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Functional plasticity in memory T helper cell responses

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Activated Akt promotes increased resting T cell size, CD28-independent T cell growth, and development of autoimmunity and lymphoma

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. II. Relative importance of glycolysis and oxidative phosphorylation on phytohaemagglutinin stimulation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3206094

Metabolic changes in activated T cells: an NMR study of human peripheral blood lymphocytes.

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21930968

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21930968

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1100367

1 reference

8 August 2017

1 reference

8 August 2017

1 reference