Detection and manipulation of phosphoinositides (Q35525004)

8 August 2017

1 reference

title

Detection and manipulation of phosphoinositides (English)

1 reference

8 August 2017

2

Pietro De Camilli

1 reference

8 August 2017

Olof Idevall-Hagren

1

1 reference

8 August 2017

language of work or name

English

0 references

publication date

13 December 2014

1 reference

Biochimica et Biophysica Acta

8 August 2017

published in

1 reference

8 August 2017

volume

1851

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8 August 2017

issue

6

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8 August 2017

page(s)

736-745

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A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells

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27 July 2018

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The uses and limitations of the analysis of cellular phosphoinositides by lipidomic and imaging methodologies.

27 July 2018

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27 July 2018

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The chemical biology of phosphoinositide 3-kinases

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27 July 2018

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Triggering actin comets versus membrane ruffles: distinctive effects of phosphoinositides on actin reorganization

27 July 2018

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Genetic interaction between MTMR2 and FIG4 phospholipid phosphatases involved in Charcot-Marie-Tooth neuropathies

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27 July 2018

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27 July 2018

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27 July 2018

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27 July 2018

1 reference

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27 July 2018

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Kinetics of PIP2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells

27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

27 July 2018

1 reference

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Visualization of cellular phosphoinositide pools with GFP-fused protein-domains

27 July 2018

1 reference

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Mutations in phosphoinositide metabolizing enzymes and human disease

27 July 2018

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Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

27 July 2018

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27 July 2018

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27 July 2018

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In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2.

27 July 2018

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PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane

27 July 2018

1 reference

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Rapidly inducible changes in phosphatidylinositol 4,5-bisphosphate levels influence multiple regulatory functions of the lipid in intact living cells

27 July 2018

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Phosphoinositides in cell regulation and membrane dynamics

27 July 2018

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Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels

27 July 2018

1 reference

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Live cell imaging of phosphoinositide dynamics with fluorescent protein domains

27 July 2018

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Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

27 July 2018

1 reference

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A plasma membrane pool of phosphatidylinositol 4-phosphate is generated by phosphatidylinositol 4-kinase type-III alpha: studies with the PH domains of the oxysterol binding protein and FAPP1.

27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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FAPPs control Golgi-to-cell-surface membrane traffic by binding to ARF and PtdIns(4)P

27 July 2018

1 reference

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The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor

27 July 2018

1 reference

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Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

27 July 2018

1 reference

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Targeting of Golgi-specific pleckstrin homology domains involves both PtdIns 4-kinase-dependent and -independent components.

27 July 2018

1 reference

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27 July 2018

1 reference

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Subcellular targeting by membrane lipids

27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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Essential role of phosphoinositide metabolism in synaptic vesicle recycling

27 July 2018

1 reference

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Visualization of phosphoinositides that bind pleckstrin homology domains: calcium- and agonist-induced dynamic changes and relationship to myo-[3H]inositol-labeled phosphoinositide pools

27 July 2018

1 reference

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27 July 2018

1 reference

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27 July 2018

1 reference

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FYVE fingers bind PtdIns(3)P

27 July 2018

1 reference

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Pten is essential for embryonic development and tumour suppression

27 July 2018

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The pleckstrin homology domain of oxysterol-binding protein recognises a determinant specific to Golgi membranes.

27 July 2018

1 reference

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Regulation of GRP1-catalyzed ADP ribosylation factor guanine nucleotide exchange by phosphatidylinositol 3,4,5-trisphosphate

27 July 2018

1 reference

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Isolation and molecular cloning of wortmannin-sensitive bovine type III phosphatidylinositol 4-kinases.

27 July 2018

1 reference

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Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002.

27 July 2018

1 reference

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A humanized system for pharmacologic control of gene expression

27 July 2018

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Dimeric ligands define a role for transcriptional activation domains in reinitiation

27 July 2018

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Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.

27 July 2018

1 reference

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A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)

27 July 2018

1 reference

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Role of synaptic phosphatidylinositol 3-kinase in a behavioral learning response in C. elegans.

27 July 2018

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Engineering genetically encoded FRET sensors.

26 September 2018

1 reference

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26 September 2018

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26 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

PIP₃ induces the recycling of receptor tyrosine kinases.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Pharmacological and genetic targeting of the PI4KA enzyme reveals its important role in maintaining plasma membrane phosphatidylinositol 4-phosphate and phosphatidylinositol 4,5-bisphosphate levels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Bioluminescent probes to analyze ligand-induced phosphatidylinositol 3,4,5-trisphosphate production with split luciferase complementation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Optical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Phosphatidylinositol 3,5-bisphosphate plays a role in the activation and subcellular localization of mechanistic target of rapamycin 1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Targeting PI3K isoforms and SHIP in the immune system: new therapeutics for inflammation and leukemia.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

RNA-guided genetic silencing systems in bacteria and archaea

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Membrane protein sequestering by ionic protein-lipid interactions

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Controlling the activity of a phosphatase and tensin homolog (PTEN) by membrane potential.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

A new wave of cellular imaging.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2).

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Loss of endocytic clathrin-coated pits upon acute depletion of phosphatidylinositol 4,5-bisphosphate.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Plasmalemmal phosphatidylinositol-4,5-bisphosphate level regulates the releasable vesicle pool size in chromaffin cells.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Multiple pools of phosphatidylinositol 4-phosphate detected using the pleckstrin homology domain of Osh2p.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Svp1p defines a family of phosphatidylinositol 3,5-bisphosphate effectors

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Production of PtdInsP3 at endomembranes is triggered by receptor endocytosis

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Phosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometry

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

A PI3-kinase signaling code for insulin-triggered insertion of glucose transporters into the plasma membrane

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

G-protein signaling through tubby proteins

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Cloning and characterization of a wortmannin-sensitive human phosphatidylinositol 4-kinase

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Membrane-Permeant Phosphoinositide Derivatives as Modulators of Growth Factor Signaling and Neurite Outgrowth

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Phosphatidylinositol 4-Kinase IIIβ Regulates the Transport of Ceramide between the Endoplasmic Reticulum and Golgi

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Analyzing phosphoinositides and their interacting proteins

15 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4863076

Receptor-induced transient reduction in plasma membrane PtdIns(4,5)P2 concentration monitored in living cells

15 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25514766

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nonradioactive analysis of phosphatidylinositides and other anionic phospholipids by anion-exchange high-performance liquid chromatography with suppressed conductivity detection

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25514766

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25514766

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.BBALIP.2014.12.008

1 reference

8 August 2017

1 reference

8 August 2017

1 reference