Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients. (Q35588670)

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scientific article published on 27 March 2015

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English	Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.	scientific article published on 27 March 2015

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3 March 2020

Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients (English)

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3 March 2020

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3 March 2020

María del Carmen Thomas

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3 March 2020

Bartolomé Carrilero

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3 March 2020

Concepción Marañón

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3 March 2020

Manuel Carlos López

7

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3 March 2020

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Manuel Segovia

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3 March 2020

Carlos Alonso

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3 March 2020

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27 March 2015

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3 March 2020

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3 March 2020

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3 March 2020

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3 March 2020

e0122115

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3 March 2020

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27 March 2015

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0 references

Chagas disease drug discovery: toward a new era.

1 reference

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27 July 2018

CD8(+) T cell-mediated immunity during Trypanosoma cruzi infection: a path for vaccine development?

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27 July 2018

Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection

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27 July 2018

Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients.

1 reference

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Depletion of Tregs for adoptive T-cell therapy using CD44 and CD137 as selection markers

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27 July 2018

Characterization of an immunodominant antigenic epitope from Trypanosoma cruzi as a biomarker of chronic Chagas' disease pathology.

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27 July 2018

Subdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.

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27 July 2018

Pathogenesis of chagas' disease: parasite persistence and autoimmunity

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27 July 2018

CD8+ T cells specific for immunodominant trans-sialidase epitopes contribute to control of Trypanosoma cruzi infection but are not required for resistance

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27 July 2018

Diagnosis, management and treatment of chronic Chagas' gastrointestinal disease in areas where Trypanosoma cruzi infection is not endemic

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Use of benznidazole to treat chronic Chagas' disease: a systematic review with a meta-analysis

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27 July 2018

Chronic human infection with Trypanosoma cruzi drives CD4+ T cells to immune senescence

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27 July 2018

CD8+ T cells in Trypanosoma cruzi infection

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27 July 2018

HLA Class I-T cell epitopes from trans-sialidase proteins reveal functionally distinct subsets of CD8+ T cells in chronic Chagas disease

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27 July 2018

Stable CD8+ T cell memory during persistent Trypanosoma cruzi infection

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27 July 2018

Drug-induced cure drives conversion to a stable and protective CD8+ T central memory response in chronic Chagas disease

1 reference

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27 July 2018

Trypanosoma cruzi infection from the view of CD8+ T cell immunity--an infection model for developing T cell vaccine

1 reference

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27 July 2018

CD8 T cell dysfunction during chronic viral infection.

1 reference

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27 July 2018

Pathogenesis of chronic Chagas heart disease

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27 July 2018

Clinical aspects of the Chagas' heart disease

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27 July 2018

T cell epitope characterization in tandemly repetitive Trypanosoma cruzi B13 protein

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27 July 2018

Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients

1 reference

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27 July 2018

Antigen-independent memory CD8 T cells do not develop during chronic viral infection

1 reference

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27 July 2018

Generation, specificity, and function of CD8+ T cells in Trypanosoma cruzi infection

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27 July 2018

Immunotherapy of Trypanosoma cruzi infection with DNA vaccines in mice

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27 July 2018

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

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27 July 2018

Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection

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27 July 2018

The use of HLA-A*0201-transfected K562 as standard antigen-presenting cells for CD8(+) T lymphocytes in IFN-gamma ELISPOT assays

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27 July 2018

DNA-Based immunization with Trypanosoma cruzi complement regulatory protein elicits complement lytic antibodies and confers protection against Trypanosoma cruzi infection

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27 July 2018

Evaluation of recombinant antigens for serodiagnosis of Chagas' disease in South and Central America.

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27 July 2018

Trypanosoma cruzi: characterization of two recombinant antigens with potential application in the diagnosis of Chagas' disease

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27 July 2018

MHC ligands and peptide motifs: first listing

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Genetic polymorphism within HLA-A*02: significant allelic variation revealed in different populations.

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Amino-terminal alteration of the HLA-A*0201-restricted human immunodeficiency virus pol peptide increases complex stability and in vitro immunogenicity

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Trypanosoma cruzi expresses diverse repetitive protein antigens

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General method for the rapid solid-phase synthesis of large numbers of peptides: specificity of antigen-antibody interaction at the level of individual amino acids

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Frequency of specific CD8+ T cells for a promiscuous epitope derived from Trypanosoma cruzi KMP-11 protein in chagasic patients.

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1 reference

https://pubmed.ncbi.nlm.nih.gov/25816096

12 December 2020

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The immunization of A2/K(b) transgenic mice with the KMP11-HSP70 fusion protein induces CTL response against human cells expressing the T. cruzi KMP11 antigen: identification of A2-restricted epitopes

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https://pubmed.ncbi.nlm.nih.gov/25816096

12 December 2020

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10.1371/JOURNAL.PONE.0122115

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3 March 2020

2015PLoSO..1022115E

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